6533b7d7fe1ef96bd1268589

RESEARCH PRODUCT

Cycloartane-type saponins from astragalus tmoleus var. tmoleus

Chiaki TanakaTomofumi MiyamotoSibel AvundukMarie Aleth Lacaille-duboisAnne Claire Mitaine-offer

subject

Pharmacologychemistry.chemical_classificationMagnetic Resonance SpectroscopybiologyTraditional medicinePlant roots010405 organic chemistryGlycosidePlant ScienceGeneral MedicineFabaceaeAstragalus PlantSaponinsbiology.organism_classification01 natural sciencesPlant Roots0104 chemical sciences010404 medicinal & biomolecular chemistryAstragalusComplementary and alternative medicinechemistryTriterpeneGenusDrug DiscoveryAstragalus Plant

description

Five known cycloartane-type glycosides were isolated from the roots of A. tmoleus Boiss. var. tmoleus. The identification of these compounds was mainly achieved by 1D and 2D NMR spectroscopic techniques and FABMS. The results of our studies confirm that triterpene saponins with the cycloartane-type skeleton might be chemotaxonomically significant for the genus Astragalus.

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