Search results for " Autonomic"

showing 10 items of 300 documents

Interrelation of peptidergic innervation with mast cells and ED1-positive cells in rat thymus

1991

The peptidergic innervation of rat thymus has been investigated by immunohistochemical methods, focusing on the spatial interrelationship of peptidergic nerve fibers with mast cells and macrophages in the rat. An antiserum directed against the protein gene product 9.5 (PGP 9.5) regarded as a pan-neuronal marker revealed a rich innervation, especially in the subcapsular cortex, in interlobular septa, and of the vasculature in the cortex and the corticomedullary boundary. A minor proportion of PGP 9.5-immunoreactive (ir) fibers supplied the thymic parenchyma. The main component of peptidergic innervation consisted of fibers costaining for tachykinins (TKs) and calcitonin gene-related peptide …

medicine.medical_specialtyPathologyNeuroimmunomodulationImmunologyVasoactive intestinal peptideConnective tissueNerve fiberThymus GlandBiologyCalcitonin gene-related peptideBehavioral NeuroscienceCatecholaminesNerve FibersInternal medicineCortex (anatomy)medicineAnimalsMast CellsGalaninEndocrine and Autonomic SystemsMacrophagesNeuropeptidesAntibodies MonoclonalCell DifferentiationRats Inbred StrainsMast cellRatsReceptors NeurotransmitterEndocrinologymedicine.anatomical_structurePeripheral nervous systemUbiquitin ThiolesteraseBiomarkersBrain, Behavior, and Immunity
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Catestatin-like immunoreactivity in the rat eye

2014

The aim of the study was to investigate the presence and distribution of the chromogranin A-derived peptide catestatin in the rat eye and trigeminal ganglion by immunofluorescence using an antibody which recognizes not only free catestatin but also larger fragments containing the sequence of catestatin. Western blots were performed in an attempt to characterize the immunoreactivities detected by the catestatin antiserum. Sparse immunoreactive nerve fibers were visualized in the corneal stroma, in the chamber angle, in the sphincter muscle but also in association with the dilator muscle, in the stroma of the ciliary body and processes, but dense in the irideal stroma, around blood vessels at…

medicine.medical_specialtyPathologygenetic structuresFluorescent Antibody TechniqueNeuropeptideSubstance PBiologyEyeCellular and Molecular NeuroscienceTrigeminal ganglionEndocrinologyCiliary bodyInternal medicinemedicineAnimalsRetinaEndocrine and Autonomic SystemsColocalizationChromogranin AGeneral MedicinePeptide Fragmentseye diseasesRatsGanglionEndocrinologymedicine.anatomical_structureTrigeminal GanglionNeurologyRats Inbred Lewbiology.proteinChromogranin Asense organsChoroidNeuropeptides
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The Role of Heart Rate on the Associations Between Body Composition and Heart Rate Variability in Children With Overweight/Obesity: The ActiveBrains …

2019

The authors would like to thank all the participants who volunteered for this investigation. This work is the part of a Ph.D. Thesis conducted in the Biomedicine Doctoral Studies of the University of Granada, Spain.

medicine.medical_specialtyPhysiologyCARDIAC AUTONOMIC MODULATIONPOWERHRV030204 cardiovascular system & hematologyOverweightlcsh:Physiology03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineHeart rateMedicine and Health SciencesmedicineHeart rate variability030212 general & internal medicineOBESEOriginal ResearchBalance (ability)adipositypreadolescentslcsh:QP1-981business.industryOverweight obesityConfoundingfat massCardiorespiratory fitnesssympatheticmedicine.diseaseObesityMARKERCardiologymedicine.symptomCARDIORESPIRATORY FITNESSbusinessparasympatheticcirculatory and respiratory physiologyFrontiers in Physiology
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The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice

2009

Oleoylethanolamide (OEA) is an endogenous lipid produced in the intestine that mediates satiety by activation of peroxisome proliferator-activated receptor alpha (PPARalpha). OEA inhibits gastric emptying and intestinal motility, but the mechanism of action remains to be determined. We investigated whether OEA inhibits intestinal motility by activation of PPARalpha. PPARalpha immunoreactivity was examined in whole mount preparations of mouse gastrointestinal (GI) tract. The effect of OEA on motility was assessed in wildtype, PPARalpha, cannabinoid CB(1) receptor and CB(2) receptor gene-deficient mice and in a model of accelerated GI transit. In addition, the effect of OEA on motility was as…

medicine.medical_specialtyPhysiologymedicine.medical_treatmentTRPV Cation ChannelsMotilityOleic AcidsBiologydigestive systemReceptor Cannabinoid CB2MiceOleoylethanolamidechemistry.chemical_compoundReceptor Cannabinoid CB1Glucagon-Like Peptide 1Internal medicinemedicineAnimalsPPAR alphaReceptorMice KnockoutGastric emptyingEndocrine and Autonomic Systemsdigestive oral and skin physiologyGastroenterologyImmunohistochemistryEndocannabinoid systemEndocrinologyMechanism of actionchemistrylipids (amino acids peptides and proteins)CannabinoidPeroxisome proliferator-activated receptor alphamedicine.symptomGastrointestinal MotilityEndocannabinoids
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The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men

2014

The role of nutritional status as determinant of successful aging is very well recognized. There is recent evidence that nutrition may exert its beneficial effects through the modulation of the hormonal anabolic milieu. Under-nutrition and anabolic hormonal deficiency frequently coexist in older individuals determining an increased risk of mobility impairment and adverse outcomes. Mineral dietary assessment has received attention as key component of the nutritional modulation of anabolic status and physical performance. There is evidence that several minerals, including magnesium, exert a positive influence on Insulin-like Growth Factor-1 (IGF-1) secretion in both sexes, and Testosterone (T…

medicine.medical_specialtySettore MED/09 - Medicina Internalcsh:RC648-665Successful agingAnabolismEndocrine and Autonomic Systemsbusiness.industryEndocrinology Diabetes and MetabolismPhysiologyTestosterone (patch)Review ArticlePhysical functionmedicine.diseaselcsh:Diseases of the endocrine glands. Clinical endocrinologyMalnutritionEndocrinologyIncreased riskEndocrinologymagnesium testosterone menInternal medicinemedicineObservational studybusinessHormoneInternational Journal of Endocrinology
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Sacubitril/Valsartan Improves Autonomic Function and Cardiopulmonary Parameters in Patients with Heart Failure with Reduced Ejection Fraction

2020

Background: Heart rate recovery (HRR) is a marker of vagal tone, which is a powerful predictor of mortality in patients with cardiovascular disease. Sacubitril/valsartan (S/V) is a treatment for heart failure with reduced ejection fraction (HFrEF), which impressively impacts cardiovascular outcome. This study aims at evaluating the effects of S/V on HRR and its correlation with cardiopulmonary indexes in HFrEF patients. Methods: Patients with HFrEF admitted to outpatients&rsquo

medicine.medical_specialtyStress testingheart failurelcsh:Medicinecardiopulmonary exercise stress testing030204 cardiovascular system & hematologyArticleSacubitril03 medical and health sciencessacubitril/valsartan heart failure heart rate recovery peak oxygen consumption autonomic function cardiopulmonary exercise stress testing0302 clinical medicineInternal medicineHeart ratemedicine030212 general & internal medicinepeak oxygen consumptionheart rate recoveryEjection fractionbusiness.industrylcsh:RGeneral Medicinemedicine.diseaseValsartansacubitril/valsartanHeart failureBreathingCardiologyautonomic functionbusinesshuman activitiesSacubitril Valsartanmedicine.drugJournal of Clinical Medicine
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Multiscale Information Decomposition Dissects Control Mechanisms of Heart Rate Variability at Rest and During Physiological Stress.

2019

Heart rate variability (HRV

medicine.medical_specialtyTechnology and Engineering0206 medical engineeringRR intervalRESPIRATORY SINUS ARRHYTHMIAPERIODGeneral Physics and Astronomysynergylcsh:Astrophysics02 engineering and technologyBiologyBaroreflexArticle03 medical and health sciences0302 clinical medicinestomatognathic systemInternal medicinelcsh:QB460-466RespirationMedicine and Health Sciencesmedicineotorhinolaryngologic diseasesHeart rate variabilitycardiovascular diseasesVagal tonelcsh:SciencePhysiological stressinformation theoryBAROREFLEXredundancyheart rate variabilityvirus diseasesmultiscale analysisEntropy cardiovascular variability redundancy autonomic nervous system020601 biomedical engineeringlcsh:QC1-999ARTERIAL-PRESSUREAutonomic nervous systemBlood pressuretime series analysisCardiologyinformation decompositionlcsh:QentropyCARDIOPULMONARYlcsh:Physics030217 neurology & neurosurgerycirculatory and respiratory physiologyEntropy (Basel, Switzerland)
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The neuroimmune link in the bronchus-associated lymphoid tissue (BALT) of cat and rat: peptides and neural markers.

1991

This light microscopic immunohistochemical study investigates the distribution and target interrelations of nerve fibers in bronchus-associated lymphoid tissues (BALT) of rat and cat by using antisera against (1) the polyneuronal marker protein gene product 9.5 (PGP 9.5), (2) selected opioid and nonopioid peptides, and (3) the marker enzymes tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH). In both species, a similar distribution pattern of PGP, peptide, and catecholamine enzyme immunoreactive was observed. Anti-PGP 9.5 stained all nerve fibers (except some smaller, calcitonin gene-related peptide-immunoreactive (CGRP-ir) fibers presumably of the C-type) throughout the differen…

medicine.medical_specialtyTyrosine 3-MonooxygenaseLymphoid TissueNeuroimmunomodulationImmunologyImmunocytochemistryMolecular Sequence DataNeuropeptideNerve fiberSubstance PBronchiCell CommunicationDopamine beta-HydroxylaseBiologyCalcitonin gene-related peptideBehavioral Neurosciencechemistry.chemical_compoundNerve FibersInternal medicinemedicineAnimalsAmino Acid SequenceMast CellsPhagocytesTyrosine hydroxylaseEndocrine and Autonomic SystemsNeuropeptidesDendritic CellsMolecular biologyProenkephalinRatsmedicine.anatomical_structureEndocrinologychemistryCatsCholinergicUbiquitin ThiolesteraseBiomarkersBrain, behavior, and immunity
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Heart Rate Variability in Children and Adolescents with Cerebral Palsy—A Systematic Literature Review

2020

Cardiac autonomic dysfunction has been reported in patients with cerebral palsy (CP). The aim of this study was to assess the existing literature on heart rate variability (HRV) in pediatric patients with CP and a special attention was paid to the compliance of the studies with the current HRV assessment and interpretation guidelines. A systematic review was performed in PubMed, Web of Science, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases searched for English language publications from 1996 to 2019 using Medical Subject Headings (MeSH) terms “heart rate variability” and “cerebral palsy” in conjunction with additional inclusion criteria: studies limited to …

medicine.medical_specialtycerebral palsyWeb of sciencebusiness.industrylcsh:Rheart rate variabilitylcsh:MedicineGeneral MedicineEnglish languageCINAHLReview030204 cardiovascular system & hematologymedicine.diseaseRESTING HEART RATECerebral palsy03 medical and health sciences0302 clinical medicineSystematic reviewPhysical medicine and rehabilitationMedicineHeart rate variabilityIn patientbusinesscardiac autonomic dysfunction030217 neurology & neurosurgeryJournal of Clinical Medicine
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ORBITAL PSEUDOTUMOR CAN MIMIC GRAVES’ OPHTHALMOPATHY

2016

CONTEXT: Orbital pseudotumor (OP) is a benign inflammatory process of the orbit with a large polymorphous lymphoid infiltrate, associated with fibrosis in variable amounts, localized or diffuse. Graves’ ophthalmopathy (GO) is the most common cause of proptosis, unilateral or bilateral. CASE REPORT: We report a patient with unilateral proptosis who was initially treated with antithyroid drugs for an euthyroid Graves disease, but the extension of the investigation infirmed this. The MRI findings (inflammation of fat, muscle and the left lacrimal gland) in conjunction with the biopsy infirmed the initial diagnostic and confirmed the OP. CONCLUSIONS: Orbital pseudotumor is a rare disorder that …

medicine.medical_specialtyendocrine systemmedicine.diagnostic_testendocrine system diseasesEndocrine and Autonomic Systemsbusiness.industryEndocrinology Diabetes and MetabolismGraves' diseaseContext (language use)TrabCase Reportmedicine.diseaseeye diseasesGraves' ophthalmopathyEndocrinologymedicine.anatomical_structureBiopsymedicineEuthyroidRadiologyDifferential diagnosisbusinessOrbit (anatomy)
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