Search results for " Biochimica"
showing 10 items of 642 documents
Deposition and characterization of Hydroxyapatite-Chitosan coatings on 304 SS for biomedical devices
2019
During the last years biomaterials have been largely investigated in order to perform and improve biomedical devices. As regards orthopedic field, the most common equipment used (such as implants, bone grafts or screws) are constituted by metallic materials (steel and titanium alloys), characterized by low/medium resistance to corrosion and low osteointegration ability. Furthermore, these factors could produce local inflammations of the tissues surrounding the implants, increasing kinetics of corrosion phenomena. Scientific community has focused the attention on biocoatings interposed between metal and aggressive environment in order to inhibit corrosion. Furthermore, these coatings are abl…
PLLA scaffolds based on thermally induced phase separation: morphology, cell seeding and proliferation
2009
PLLA biodegradable scaffolds for Vascular Tissue Engineering (VTE) applications via dip drawing and Diffusion Induced Phase Separation (DIPS)
2009
Poly lactic acid based scaffolds for vascular tissue engineering
2012
A critical obstacle encountered by tissue engineering is the inability to maintain large masses of living cells upon transfer from the in vitro culture conditions to host in vivo. Capillaries, and the vascular system, are required to supply essential nutrients, including oxygen, remove waste products and provide a biochemical communication "highway". The successful use of tissue-engineered constructs is currently limited to thin or avascular tissues, such as skin or cartilage, for which post-implantation neovascularisation from the host is sufficient to meet the demand for oxygen and nutrients. To succeed in the application of tissue engineering for bigger tissues, such as bone or muscle, t…
Polyactide Biodegradable Scaffolds for Tissue Engineering Applications: Phase Separation-Based Techniques
2011
One of the most reliable techniques for the preparation of biodegradable scaffolds suitable for tissue engineering applications (e.g. regeneration of wounded/damaged tissues) is based on liquid/liquid phase separation of ternary solvent/antisolvent/polymer solutions. In particular, two phase separation protocols are examined here: Thermally Induced Phase Separation (TIPS) and Diffusion Induces Phase Separation (DIPS). According to the former protocol, a thermodynamically stable polymeric ternary solution is brought below its metastability/instability point (spinodal/binodal curve) by quench in a cooling medium: under opportune conditions, a foam-like structure is formed by nucleation and 3-…
Lactate level and handgrip test in migraine and fibromyalgia after self-myofascial release treatment
2019
The Aim of the study was to determine the effect of self-myofascial release (SMFR) treatment on handgrip test score in patients with fibromyalgia and migraine, investigating also if the lactate levels influenced the result. Twenty-five subjects affected by migraine (age 49.7±12.5; height 164.9±6.62 cm; weight 68.6±16.9 kg) and ten subjects affected by fibromyalgia (age 43.7±21.2; height 158±5.65 cm; weight 70±28.9 kg) were enrolled in the study. The assessments included a handgrip test, in order to evaluate isometric strength of both hands and forearm muscles and the lactate levels evaluation. The treatment was performed in the three most painful trigger points indicated from subjects as to…
Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Rel…
2023
: Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The Mediterranean diet is a non-invasive intervention to improve the chronic low-grade inflammatory status associated with aging. Olive oil oleuropein (OLE) and hydroxytyrosol (HT) demonstrated a controversial modulatory action on inflammation in vitro when tested at concentrations exceeding those detectable in human plasma. We studied the potential anti-inflammatory effects of OLE and HT at nutritionally relevant concentrations on peripheral blood mononuclear cells (PBMCs) as regards cell viability, frequency of leukocyte subsets, and cytokine release, performing an age-focused analysis on two groups of subj…
Impact of Mycobacterium tuberculosis Infection on Human B Cell Compartment and Antibody Responses
2022
Tuberculosis (TB) remains one of the most important health challenges worldwide. Control of the TB epidemic has not yet been achieved because of the lack of an effective vaccine and rapid and sensitive diagnostic approaches, as well as the emergence of drug-resistant forms of M. tuberculosis. Cellular immunity has a pivotal role against M. tuberculosis infection, but the role of humoral immunity is still controversial. We analyzed the frequency, absolute counts, and phenotypic and functional subsets of B lymphocytes in the peripheral blood of patients with active TB and subjects with latent infection compared to healthy donors. Moreover, we analyzed serum levels of total Ig and their IgA, I…
Erratum: FragClust and TestClust, two informatics tools for chemical structure hierarchical clustering analysis applied to lipidomics. The example of…
2016
Erratum to: FragClust and TestClust, two informatics tools for chemical structure hierarchical clustering analysis applied to lipidomics. The example of Alzheimer’s disease
Rat CNS neurons are not yet programmed to shorten their chromatin repeat length at the end of fetal neurogenesis.
1986
Neurons from rat fetal cerebral hemispheres were grown in a synthetic medium (Maat medium), as previously described, for different periods of time. The repeat length of their chromatin was determined by micrococcal nuclease digestion and compared with that of neurons isolated from postnatal rat brain of corresponding ages. In contrast to the in vivo situation, we found that neurons, dissociated at the 16th gestational day and cultured in vitro, did not undergo the shortening of their chromatin repeat, thus indicating that, at the end of their mitotic cycles, they are not yet programmed to this event. © 1986.