Search results for " CAS"

showing 10 items of 2828 documents

Diagnosis and treatment for central Mucoepidermoid Carcinoma in the mandible: Report of a clinical case in a young patient

2019

A clinical case of a 13 year old male patient with a malignant tumor in the mandibular body area with two years of evolution and associated pain is reported. It was initially diagnosed as low grade central mucoepidermoid carcinoma through Hematoxylin and Eosin (H-E) staining in multiple biopsies. Considering the clinical and radiographic characteristics of the lesion, it was necessary to confirm the diagnosis through Periodic acid-Schiff (PAS). The treatment involved hemimandibulectomy, neck emptying, and complementary radiotherapy. This article aims to present a rare occurrence of this type of intraosseous malignant tumor of glandular origin in a young patient. Key words:Mucoepidermoid car…

medicine.medical_specialtyOral Medicine and Pathologybusiness.industrymedicine.medical_treatmentRadiographyH&E stainMandibleCase Reportmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Radiation therapyLesionHemimandibulectomyMucoepidermoid carcinomaUNESCO::CIENCIAS MÉDICASmedicineRadiologyClinical casemedicine.symptombusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Melanoma of the oral mucosa with cerebral metastasis: a clinical case

2005

Summary Oral melanoma (OM) is an infrequent neoplasia making up less than 1% of all melanomas, and which exhibits a much more aggressive behaviour than those found on the skin. We present a case of OM located on the hard palate, vestibular alveolar gingiva of the maxilla, and upper lip in a 75-year-old patient who developed a distant metastasis on the left parietal lobe. The advanced stage of the disease contraindicated any surgical intervention and it was decided to carry out palliative radiotherapy, but the patient died before treatment.

medicine.medical_specialtyOral melanomabusiness.industryMelanomamedicine.diseaseOral melanomaPathology and Forensic MedicineSurgeryCerebral metastasisOral pigmentationstomatognathic diseasesHead and neckmedicine.anatomical_structureOncologyOtorhinolaryngologystomatognathic systemPalliative radiotherapyMaxillamedicineCerebral metastasisHard palateClinical caseOral SurgeryOral mucosabusinessOral Oncology Extra
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A rare case of oral multisystem Langerhans cell histiocytosis

2017

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of Langerhans dendritic cells. LCH is a solitary or multifocal disease that primarily involves bone tissue and often affects children and young men. A 29 years-old Caucasian man was referred to the Oral Surgery Unit of George Eastman Hospital - Umberto I teaching hospital, with third degree mobility of teeth belonging to second, third and fourth quadrant. Panoramic radiograph showed multiple radiolucent areas with well demarcated borders on the right and left site of the mandible and on the left site of the maxilla. Extractions of compromised teeth and biopsy of the osteolytic tissue were performed. T…

medicine.medical_specialtyPanoramic radiographDifferential diagnosis; Langerhans cell histiocytosis; Microscopic diagnosis; Dentistry (all)Case ReportSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE03 medical and health sciencesQuadrant (abdomen)0302 clinical medicineLangerhans cell histiocytosisRare caseBiopsymedicineGeneral DentistryOral Medicine and Pathologymedicine.diagnostic_testbusiness.industrySoft tissueLangerhans cell histiocytosis030206 dentistryMicroscopic diagnosismedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologySurgery030220 oncology & carcinogenesisMaxillaUNESCO::CIENCIAS MÉDICASDentistry (all)Proper treatmentDifferential diagnosisbusiness
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Ossifying odontogenic fibroma: A rare case report

2014

Odontogenic fibroma (OF) is a rare benign odontogenic neoplasm that is most commonly found in the mandibular/premolar region of female patients in the second to fourth decades of life. Well-defined radiolucent lesions that may induce root resorption are normally observed. Rare variants of OF have been described in the prior literature, including references to: 1) giant cell lesions, 2) amyloid-like protein deposition, and 3) ossifying variants. Immunohistochemistry can contribute to understanding the biological behavior and the pathogenesis of OF. Therefore, this case report aimed to describe a new case of ossifying OF and discuss the histopathology and immunohistochemical features. Key wor…

medicine.medical_specialtyPathologyOral Medicine and Pathologybusiness.industryOdontologíaCase ReportRoot resorption:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludBenign Odontogenic NeoplasmOdontogenic Fibromastomatognathic diseasesmedicine.anatomical_structureGiant cellUNESCO::CIENCIAS MÉDICASFemale patientRare casemedicinePremolarHistopathologybusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Pityriasis rosea Gibert triggered by SARS-CoV-2 infection: A case report.

2021

RATIONALE: Pityriasis rosea Gibert is an erythematous-papulosquamous dermatosis that frequently occurs in young adults. The etiopathogenesis of PR is still unknown, but is frequently associated with episodes of upper respiratory tract infections. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PATIENT CONCERNS: We present the case of a female patient in whom the diagnosis of pityriasis rosea led to the investigation and diagnosis of the SARS-CoV-2 infection. The patient presented to the Department of Dermatology for a 3 week duration of an extremely pruritic erythematous-squamous lesion, initially on the trunk …

medicine.medical_specialtyPityriasis RoseaContext (language use)Lesion03 medical and health sciencescoronavirus disease 20190302 clinical medicineAdrenal Cortex HormonesmedicineHumans030212 general & internal medicineClinical Case ReportRespiratory tract infectionsbusiness.industrySARS-CoV-24900COVID-19pityriasis rosea GibertGeneral MedicineMiddle Agedmedicine.diseaseDermatologyRashTopical medicationmedicine.anatomical_structure030220 oncology & carcinogenesisPityriasis roseaEtiologyFemalemedicine.symptombusinessRespiratory tractResearch Articlesevere acute respiratory syndrome coronavirus 2Medicine
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An unusual case of postcholecystectomy syndrome.

2019

medicine.medical_specialtyPostcholecystectomy syndromemedicine.medical_treatmentMEDLINEYoung AdultImaging Three-DimensionalPancreaticobiliary MaljunctionmedicineHumansRadiology Nuclear Medicine and imagingCholangiopancreatography Endoscopic RetrogradeUnusual casemedicine.diagnostic_testbusiness.industryGeneral surgeryGastroenterologyCystic DuctMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingCholecystectomy LaparoscopicCholedochal CystCholecystectomyFemalebusinessPostcholecystectomy SyndromeGastrointestinal endoscopy
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Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repagl…

2004

The 11 C-labeled sulfonylurea receptor 1 (SUR1) ligand (S)-2-(( 11 C)methoxy)-4-(3-methyl-1-(2-piperidine-1-yl-phenyl)- butyl-carbamoyl)-benzoic acid (( 11 C)methoxy-repaglinide) was synthesized in an overall radiochemical yield of 35% after 55 min with a radiochemical purity higher than 99%. This compound is considered for the noninvasive investigation of the SUR1 receptor status of pancreatic b-cells by positron emission tomography (PET) in the context of type 1 and type 2 diabetes. The specific activity was 40-70 GBq/lmol. In vitro testing of the nonradioactive methoxy-repaglinide was performed to characterize the affinity for binding to the human SUR1 isoform. Methoxy-repaglinide induce…

medicine.medical_specialtyPotassium Channelsmedicine.medical_treatmentReceptors DrugClinical BiochemistryPharmaceutical ScienceType 2 diabetesIn Vitro TechniquesSulfonylurea ReceptorsBiochemistryBenzoatesBinding CompetitiveIslets of LangerhansPiperidinesDiabetes mellitusInternal medicineDrug DiscoveryInsulin SecretionmedicineAnimalsHumansInsulinCarbon RadioisotopesPotassium Channels Inwardly RectifyingMolecular BiologyIC50Type 1 diabetesChemistryInsulinOrganic ChemistryStereoisomerismmedicine.diseaseRepaglinideLigand (biochemistry)RatsEndocrinologyPositron-Emission TomographyCOS CellsMolecular MedicineSulfonylurea receptorATP-Binding Cassette TransportersCarbamatesRadiopharmaceuticalsHydroxybenzoate Ethersmedicine.drugBioorganicmedicinal chemistry letters
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Synergistic effects of fluticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma

2004

Background In asthma T cells are characterized by an increased activation state and by reduced apoptosis. Objective Because the clinical efficacy of inhaled corticosteroids combined with long-acting β 2 -agonists has been widely demonstrated in asthma, we studied, in vitro , the effect of fluticasone propionate (FP) and salmeterol alone and in combination on the activation and apoptosis of peripheral blood T cells (PBTs), on the expression of phosphorylated nuclear factor κB inhibitor (IκBα), and on the nuclear translocation of glucocorticoid receptor (GR) in PBTs from asthmatic subjects. Methods Apoptosis was evaluated on the basis of annexin V binding, whereas the expression of caspases 8…

medicine.medical_specialtyProgrammed cell deathAdolescentT cellT-LymphocytesImmunologyActive Transport Cell NucleusApoptosisAndrostadienes; Active Transport Cell Nucleus; NF-kappa B; Apoptosis; Humans; Albuterol; Receptors Glucocorticoid; Asthma; Child; Caspases; Lymphocyte Activation; Phosphorylation; I-kappa B Proteins; Adolescent; Drug Synergism; T-LymphocytesLymphocyte ActivationGlucocorticoid receptorReceptors GlucocorticoidNF-KappaB Inhibitor alphaAnnexinInternal medicinemedicineHumansImmunology and AllergyAlbuterolPhosphorylationChildSalmeterol XinafoateAndrostadieneChemistryActive Transport Cell NucleuNF-kappa BApoptosiDrug SynergismCaspaseAsthmaAndrostadienesIκBαEndocrinologymedicine.anatomical_structureApoptosisCaspasesFluticasoneI-kappa B ProteinI-kappa B ProteinsSalmeterolGlucocorticoidmedicine.drugHuman
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A rare case of ruptured aneurysm of the paramedian artery of Percheron.

2018

Introduction The artery of Percheron is a rare anatomic variant supplying bilateral medial thalamic nuclei and a variable portion of the rostral part of midbrain. Case report A 48-year-old female with massive subarachnoid hemorrhage due to a ruptured aneurysm of the paramedian artery of Percheron presented to the emergency room. Because of significant risk of recurrent intracranial hemorrhage, it was decided to proceed with endovascular embolization of the aneurysm. The patient was ultimately sent to a rehabilitation center and her presenting neurologic deficits showed significant improvements in the weeks following endovascular embolization treatment. Discussion The paramedian artery of Pe…

medicine.medical_specialtyRadiology Nuclear Medicine and ImagingSubarachnoid hemorrhagemedicine.medical_treatmentAneurysm RupturedArtery of Percheron030218 nuclear medicine & medical imagingArtery of percheron03 medical and health sciences0302 clinical medicineAneurysmThalamusMesencephalonRare casemedicineHumansEmbolizationSignificant riskcardiovascular diseasesArterial anatomybusiness.industryAnatomic VariationIntracranial AneurysmCerebral ArteriesMiddle AgedSubarachnoid Hemorrhagemedicine.diseaseEmbolization TherapeuticAneurysmSurgerymedicine.anatomical_structureruptured cerebral aneurysmFemaleNeurology (clinical)businessCardiology and Cardiovascular Medicine030217 neurology & neurosurgeryArteryInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
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Double localization and multiple recurrences of dermatofibrosarcoma protuberans of the female breast: a rare clinical case.

2015

Not available

medicine.medical_specialtySkin NeoplasmsMEDLINEBreast NeoplasmsNeoplasm RecurrenceInternal MedicinemedicineDermatofibrosarcoma protuberansBreast Neoplasms; Dermatofibrosarcoma; Female; Humans; Middle Aged; Neoplasm Recurrence Local; Skin Neoplasms; Internal Medicine; Oncology; Surgery; Medicine (all)HumansSkin NeoplasmUltrasonographybusiness.industryMedicine (all)DermatofibrosarcomaMiddle Agedmedicine.diseaseSurgeryOncologySurgeryFemaleRadiologyClinical caseUltrasonographyNeoplasm Recurrence LocalbusinessBreast NeoplasmDermatofibrosarcomaHumanThe breast journal
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