Search results for " CAVITY"

showing 10 items of 472 documents

Noninvasive Monitoring of Lesion Size in a Heterologous Mouse Model of Endometriosis

2019

Here, we describe a protocol for the implementation of a heterologous mouse model in which progression of endometriosis can be assessed in real time through noninvasive monitoring of fluorescence emitted by implanted ectopic human endometrial tissue. For this purpose, biopsies of human endometrium are obtained from donor women ongoing oocyte donation. Human endometrial fragments are cultured in the presence of adenoviruses engineered to express cDNA for the reporter fluorescent protein mCherry. Upon visualization, labeled tissues with an optimal rate of fluorescence after infection are subsequently chosen for the implantation in recipient mice. One week prior to the implantation surgery, re…

0301 basic medicinePathologymedicine.medical_specialtyGeneral Chemical EngineeringEndometriosisEndometriosisHeterologousTransfectionGeneral Biochemistry Genetics and Molecular BiologyLesion03 medical and health sciencesPeritoneal cavityMice0302 clinical medicineIn vivomedicineAnimalsHumansGeneral Immunology and Microbiologybusiness.industryGeneral Neurosciencemedicine.diseaseFluorescence intensityDisease Models Animal030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisFemalemedicine.symptommCherrybusinessPreclinical imagingJournal of Visualized Experiments
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3-Dimensional Analysis and Systematic Review of Root Canal Morphology and Physiological Foramen Geometry of 109 Mandibular First Premolars by Micro-c…

2019

Abstract Introduction The aim of this study was to systematically revise the root canal configuration (RCC) literature and to investigate the root canal morphology of mandibular first premolars (Ma1Ps) of 2 populations by means of micro–computed tomographic imaging. Methods This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines including RCC randomized controlled trials and cross-sectional, cohort, comparative, validation, and evaluation studies. Furthermore, the RCC, physiological foramina, the frequency of accessory and connecting canals, and the physiological foramina morphology of 109 Ma1Ps were investigated by means of micro–co…

0301 basic medicineRoot canalPopulationMandible03 medical and health sciences0302 clinical medicinemedicineForamenBicuspidTooth RooteducationGeneral DentistryOrthodonticseducation.field_of_studySystem codebusiness.industryMicro computed tomography030206 dentistryRoot canal morphologyMandibular first premolarX-Ray Microtomography030104 developmental biologymedicine.anatomical_structureCross-Sectional StudiesWide diameterDental Pulp CavitybusinessSwitzerlandJournal of endodontics
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Root Canal Morphology of 116 Maxillary Second Premolars by Micro–Computed Tomography in a Mixed Swiss-German Population with Systematic Review

2020

Abstract Introduction The aim of this investigation was to examine the root canal system morphology of maxillary second premolars (Mx2Ps) of a Swiss-German population by means of micro–computed tomography and provide systematic review of the root canal configuration (RCC) literature of Mx2Ps. Methods The RCC, main foramina as well as accessory canals and foramina frequency of 116 Mx2Ps, were investigated by means of micro–computed tomography and 3-dimensional software imaging. The RCC from the coronal to apical thirds of the root as well as the main foramina number were described by using a four-digit system code. The literature review follows the PRISMA guideline analyzing randomized contr…

0301 basic medicineRoot canalPopulationurologic and male genital diseases03 medical and health sciences0302 clinical medicineMaxillaForamenHumansMedicineBicuspidTooth RooteducationGeneral DentistryOrthodonticseducation.field_of_studySystem codebusiness.industryMicro computed tomographyX-Ray Microtomography030206 dentistryRoot canal morphologyCross-Sectional Studies030104 developmental biologymedicine.anatomical_structureCoronal planeDental Pulp CavitybusinessMaxillary second premolarSwitzerlandJournal of Endodontics
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Collapsibility of the internal jugular veins in the lateral decubitus body position: A potential protective role of the cerebral venous outflow again…

2019

Recent research has revealed that patients with neurodegenerative disease sleep longer in the supine position, while healthy controls prefer sleeping in the lateral decubitus position. Thus, sleeping in the lateral position seems to be protective against neurodegeneration. It has also been suggested that a protective role of this body position could be associated with better cerebral venous drainage in this body position, which results in more active glymphatic system of the brain (the system responsible for clearance of the cerebral tissue from waste products, e.g. amyloid-β). Since no published evidence exists regarding venous outflow from the cranial cavity in the lateral decubitus posit…

0301 basic medicineSupine positionModels NeurologicalPostureBlood PressurePilot ProjectsLateral decubitus positionSitting03 medical and health sciencesHabits0302 clinical medicineAlzheimer DiseaseReference Valuesmental disordersCranial cavitymedicineLateral Decubitus PositionSupine PositionHumansNeurodegenerationInternal jugular veinhealth care economics and organizationsUltrasonographyRight Lateral Decubitus PositionAquaporin 4business.industryNeurodegenerationHemodynamicsGeneral MedicineAnatomyAlzheimer's diseasemedicine.diseaseCerebral Veins030104 developmental biologymedicine.anatomical_structureCerebrovascular CirculationPulsatile FlowNerve Degenerationcardiovascular systemInternal jugular veinGlymphatic systemJugular VeinsbusinessSleepGlymphatic System030217 neurology & neurosurgeryBlood Flow VelocityMedical hypotheses
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3-dimensional Analysis and Literature Review of the Root Canal Morphology and Physiological Foramen Geometry of 125 Mandibular Incisors by Means of M…

2019

Abstract Introduction The aim of this study was to examine the root canal system morphology of mandibular incisors by means of micro–computed tomographic imaging. Methods The root canal configuration, physiological foramina, frequency of accessory and connecting canals, and the size and shape of the physiological foramina of 125 mandibular incisors were investigated by means of micro-CT and 3-dimensional imaging software. Root canal configuration of the coronal, middle, and apical thirds and the physiological foramina number are described by a 4-digit system code. Results The most frequent root canal configurations were 1-1-1/1 (56%), 1-2-1/1 (17.6%), and 1-1-1/2 (10.4%); 9 additional diffe…

0301 basic medicineSystem codeRoot canalMicro computed tomographyMandibleX-Ray Microtomography030206 dentistryAnatomyRoot canal morphologyBiologyRoot Canal TherapyIncisor03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureGerman populationCoronal planemedicineForamenHumansDental Pulp CavityTooth RootGeneral DentistryAnterior teethJournal of Endodontics
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Lubricin in synovial fluid of mild and severe temporomandibular joint internal derangements

2015

Background To understand the molecular basis of temporomandibular joint (TMJ) pathologies, we aimed to investigate the lubricin levels in the TMJ synovial fluid (SF) of patients with mild to severe internal derangements (IDs). Material and Methods A total, 34 joints were the study group. Only patients, with a Wilkes stage of III, IV and V were included, in this sample. Control group consisted of SF from eight joints, from patients undergoing to orthognatic surgery. Concentrations of lubricin in the SF from both samples were measured using ELISA system. Results The mean lubricin concentration was 7.029 ± 0.21 µg/mL in stage III patients; 5.64 ± 0.10 µg/mL in stage IV patients, and 4.78 ± 0.1…

0301 basic medicinemedicine.medical_specialtyJoint cavitylubricin; synovial fluid; TMJGastroenterology03 medical and health sciences0302 clinical medicinesynovial fluidDisease severityInternal medicinemedicineHumansSynovial fluidStage (cooking)General DentistryGlycoproteinsVas scoreTemporomandibular Jointbusiness.industryResearch030206 dentistryTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]Control subjectsTMJTemporomandibular jointSurgeryOrofacial Pain-TMJDCross-Sectional Studies030104 developmental biologymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgerylubricinStage ivbusiness
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Influence of platelet-derived growth factor on osseous remodeling properties of a variable-thread tapered dental implant in vivo

2016

Objectives To evaluate the effect of platelet-derived growth factor (rhPDGF-BB) on the promotion of osteogenesis around variable-thread tapered implants in an animal model. Material and methods Twenty-four variable-thread tapered implants were inserted in the tibia of 12 rabbits. Twelve sites received additional rhPDGF-BB released from a presoaked xenogenic bone block that was fixed supracrestally. Primary outcomes were bone-to-implant contact (BIC; in % ± SD) and percentage of medullary bone fill around the implants (PMF; in % ± SD) after 3 weeks (PDGF n = 6, no PDGF n = 6) and 6 weeks (PDGF n = 6, no PDGF n = 6). Results Considerable crestal and medullary bone remodeling could be found ar…

0301 basic medicinemedicine.medical_specialtyPlatelet-derived growth factorMedullary cavitymedicine.medical_treatmentDentistryOsseointegrationBone remodeling03 medical and health scienceschemistry.chemical_compound0302 clinical medicineImplants ExperimentalInternal medicinemedicineAnimalsProspective StudiesTibiaDental implantDental ImplantsPlatelet-Derived Growth FactorTibiabiologybusiness.industryGrowth factor030206 dentistry030104 developmental biologyEndocrinologychemistryModels Animalbiology.proteinBone RemodelingRabbitsOral SurgerybusinessPlatelet-derived growth factor receptorClinical Oral Implants Research
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Sweeteners and sweetness enhancers

2017

indexation en cours; PURPOSE OF REVIEW: The current review summarizes and discusses current knowledge on sweeteners and sweetness enhancers. RECENT FINDINGS: The perception of sweet taste is mediated by the type 1 taste receptor 2 (T1R2)/type 1 taste receptor 3 (T1R3) receptor, which is expressed in the oral cavity, where it provides input on the caloric and macronutrient contents of ingested food. This receptor recognizes all the compounds (natural or artificial) perceived as sweet by people. Sweeteners are highly chemically diverse including natural sugars, sugar alcohols, natural and synthetic sweeteners, and sweet-tasting proteins. This single receptor is also the target for developing …

0301 basic medicineobesitysweetener[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionreceiverMedicine (miscellaneous)PharmacologyOral cavityReceptors G-Protein-Coupled03 medical and health sciencesSugar AlcoholsTaste receptorgoût sucréDietary CarbohydratesAnimalsHumansSteviaMedicinesweet taste receptorNutrition and Dieteticsbusiness.industrydigestive oral and skin physiologyTaste Perceptionfood and beveragesSweet tasteSweetnessobésité030104 developmental biologycarbohydrateSweetening AgentsTastebusinessrécepteur[SDV.AEN]Life Sciences [q-bio]/Food and Nutritiondiabète
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Detection of Candida albicans biofilm proteins induced by glucose, lactose, soy protein, and iron

2019

Background Oral candidiasis is one of the most common fungal infections, which attack the mucosa of the oral cavity. These lesions are mostly caused by the fungal species Candida albicans. Candida albicans is included in the normal oral microorganisms that are opportunistic pathogens, and its presence is quite large, which can reach 75% of the total oral fungal population. Research on specific proteins of Candida biofilm can be an alternative to early prevention of oral infections such as Oral Candidiasis. This biofilm protein can be used as a reference in making kits to detect the presence of microbes that cause infectious diseases. The purpose of this study was to determine molecular weig…

0303 health sciencesbiologyProtein band030306 microbiologyChemistryMicroorganismBiofilmExperimental laboratoryOral cavitybiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Microbiology03 medical and health scienceschemistry.chemical_compoundUNESCO::CIENCIAS MÉDICASLactoseCandida albicansGeneral DentistrySoy protein030304 developmental biology
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Low repetition rate gain-switched double-clad thulium-doped fiber laser operating in the 2 µm wavelength region

2021

Abstract The experimental demonstration of a gain-switched pulsed fiber laser with low repetition rate emission in the 2 µm wavelength region is presented. The laser cavity is based on the figure-9 shape, where the gain-switched operation of the laser is obtained by using a double-clad Tm-doped fiber (DCTDF) as gain medium and a commercial pulsed laser diode at 793-nm with configurable parameters as pump source. The pulse parameters of the pump source are optimized for efficient suppressing of unstable gain-switched laser oscillations. As a result, laser pulses with low repetition rate in a range from 10 to 20 kHz with laser emission at the wavelength of 1951 nm are obtained. The generated …

Active laser mediumMaterials sciencebusiness.industryPhysics::Opticschemistry.chemical_elementLaserAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic Materialslaw.inventionWavelengthThuliumchemistryControl and Systems EngineeringlawFiber laserOptical cavityOptoelectronicsFiberElectrical and Electronic EngineeringbusinessInstrumentationDiodeOptical Fiber Technology
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