Search results for " CIO"
showing 10 items of 50 documents
Characterization and metal-induced gene transcription of two new copper zinc superoxide dismutases in the solitary ascidian Ciona intestinalis
2013
Antioxidant enzymes are known to protect living organisms against the oxidative stress risk, also induced by metals. In the present study, we describe the purification and molecular characterization of two Cu,Zn superoxide dismutases (SODs), referred to as Ci-SODa and Ci-SODb, from Ciona intestinalis, a basal chordate widely distributed in temperate shallow seawater. The putative amino acid sequences were compared with Cu,Zn SODs from other metazoans and phylogenetic analyses indicate that the two putative Ci-SODs are more related to invertebrate SODs than vertebrate ones. Both phylogenetic and preliminary homology modeling analyses suggest that Ci-SODa and Ci-SODb are extracellular and int…
A CONFIGURAÇÃO INOVADORA DO PRINCÍPIO DA BOA ADMINISTRAÇÃO ENTRE PRIVADOS E AUTORIDADES PÚBLICAS NA UNIÃO EUROPÉIA
2017
O direito a uma boa administração pública é um dos direitos fundamentais da pessoa, garantido pelo artigo 41 da Carta dos direitos fundamentais da União Europeia, que, em 2009, por força do Tratado de Lisboa, tornou-se juridicamente vinculante com o mesmo valor de fonte primária dos Tratados europeus. Ele é definido como o direito de cada pessoa (física e jurídica) de receber, por parte da autoridade pública, em relação às questões que se lhe refiram, um tratamento imparcial, equitativo e num prazo razoável. Inclui, também, os seguintes direitos de natureza procedimental: a ser ouvida, antes de, a seu respeito, ser tomada qualquer medida individual que a afete desfavoravelmente; a ter acess…
The conservation and diversity of ascidian cells and molecules involved in the inflammatory reaction: The Ciona robusta model
2021
Ascidians are marine invertebrate chordates belonging to the earliest branch (Tunicata) in the chordate phylum, therefore, they are of interest for studying the evolution of immune systems. Due to the known genome, the non-colonial Ciona robusta, previously considered to be C. intestinalis type A, is a model species for the study of inflammatory response. The internal defense of ascidians mainly relies on hemocytes circulating in the hemolymph and pharynx. Hemocytes can be in vivo challenged by LPS injection and various granulocyte and vacuolated cell populations differentiated to produce and release inflammatory factors. Molecular biology and gene expression studies revealed complex defens…
Reliģiskā cionisma kustība Latvijā: vēsture, organizācijas, ietekme
2014
Anotācija Šī promocijas darba mērķis ir kritiski analizēt un pētīt reliģiskā cionisma vēsturisko attīstību, īpaši fokusējoties uz tā aspektiem Latvijas teritorijā. Detalizēti pētīts tiek reliģiskā cionisma ideju iespaids uz ebreju garīgās domas reliģiskajiem un politiskajiem aspektiem. Šī darba tēze ir: Izšķiroša loma reliģiskā cionisma attīstībā bija Latvijas rabīnu teoloģiskiem skaidrojumiem un Latvijas reliģiskā cionisma politisko līderu darbībai. Darbā tiek aplūkots plašs reliģiskā cionisma spektrs, pētījums sākas ar rabīnu J. Alkalaja un Z. Kališera pirmajām proto-cionisma idejām, turpinās ar modernā reliģiskā cionisma ideju pamatlicēju Bauskas rabīnu M. Eliasberga un A.I. Kuka garīgās…
Formaggio al cioccolato, promettente abbinamento sensoriale e salutistico
2021
Il formaggio al cioccolato ottenuto combinando due alimenti tradizionali, il pecorino ed il cioccolato di Modica IGP, può rappresentare un prodotto lattiero caseario innovativo e funzionale
Screening of Ovarian steroidogenic pathway in Ciona intestinalis and its modulation after Tributyltin exposure
2010
In this study, we have identified several ovarian steroids in Ciona with high similarity to vertebrate steroids and showed that cholesterol, corticosterone, dehydroepiandrosterone, estrone, estradiol-17beta, testosterone, pregnenolone, progesterone, have identical molecular spectra with vertebrate steroids. In addition, we have studied the effects of an endocrine disruptor (tributyltin: TBT) on these sex hormones and their precursors, ovarian morphology, and gene expression of some key enzymes in steroidogenic pathway in the ovary of Ciona. Ovarian specimens were cultured in vitro using different concentrations of TBT (10{sup -5}, 10{sup -4} and 10{sup -3} M). Ethanol was used as solvent co…
A biochemical study of the effects of tributyltin on unfertilized eggs, embryos and larvae of the sea squirt Ciona intestinalis
2009
We have used unfertilized eggs, embryos and larvae of the sea squirt Ciona intestinalis (Ascidiacea, Urochordata) to study the effects of tributyltin (TBT) on acetylcholine esterase (AChE) activity. Our results showed an increase of AChE enzyme activity levels after TBT exposure in both unfertilized eggs and embryos. The effects of TBT were more pronounced during the gastrula stage, while no differences between exposed larvae and controls were observed. A mechanism of TBT action on enzyme activity during ascidian embryonic development and the possibility of employing AChE in C. intestinalis as a biomarker of TBT exposure are suggested and discussed.
Immunolocalization and involvement of antimicrobial peptides in local inflammatory-like reactions in the tunic of Ciona intestinalis (Tunicata).
2011
La malattia per la morte e l’eutanasia. Tentativo di un pensiero ai confini dell’abisso
2003
Sul commercio librario tra Palermo e Napoli. Un'inedita fonte seicentesca
2020
An unpublished source regarding book trade is considered here: the 1628 commercial transaction diary by Leonardo Paulini (on behalf of the Venetian bookseller Francesco Ciotti, active in Palermo at that time), rich in information regarding buying/selling (and barter) business in Naples with different publishers/printer and booksellers. The diary is in manuscript form and today is kept in Treviso, Municipal Library.