Search results for " COMPLICATIONS"

showing 10 items of 1417 documents

Effect of non-surgical periodontal treatment with or without doxycycline on the periodontium of type 1 diabetic patients

2005

Aim: The present investigation was performed to study how type 1 diabetics responded to non-surgical periodontal treatment with and without adjunctive doxycycline. Method: Sixty diabetic type 1 patients (mean age 35.3 +/- 9 years) with moderate-to-severe periodontal disease were selected and divided into two groups of 30 patients each. Both groups were sex and age matched and had similar amounts of periodontal destruction. Plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment levels (CAL) were recorded. Group 1 (30 patients) was treated with oral hygiene instruction, scaling and root planing, chlorhexidine rinses twice a day and doxycycline (100 mg/day for…

AdultMaleTime Factorsroot planingBleeding on probingperiodontal diseaseDentistrylaw.inventionDiabetes ComplicationsScaling and root planingRandomized controlled triallawDiabetes mellitusmedicineHumansSingle-Blind MethodPeriodontal DiseasesDoxycyclinediabetesdoxycyclinebusiness.industryDental Plaque IndexChlorhexidinePeriodontiumMiddle Agedmedicine.diseaseDental Plaque IndexAnti-Bacterial AgentsDiabetes Mellitus Type 1Treatment OutcomeDental Care for Chronically IllDoxycyclineDental ScalingPeriodonticsFemaleperiodontal therapyPeriodontal Indexmedicine.symptombusinessmedicine.drugJournal of Clinical Periodontology
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Inverse regulation of vascular endothelial growth factor and VHL tumor suppressor gene in sporadic renal cell carcinomas is correlated with vascular …

1999

Tumors associated with the VHL (von Hippel-Lindau) disease, such as hemangioblastomas and renal carcinomas and their sporadic counterparts, are cystic and well vascularized. Mutations of the VHL tumor-suppressor gene and elevated levels of vascular endothelial growth factor (VEGF) have been described in these tumors. The upregulation of VEGF has been shown in vitro as a consequence of alteration of the VHL gene. No comprehensive in vivo analysis has yet been carried out of the factors affecting tumor growth, vascularization, VEGF, and VHL expression. We performed immunohistochemistry and mRNA studies on primary sporadic renal carcinomas and matching normal renal tissue. We semiquantitativel…

AdultMaleVascular Endothelial Growth Factor APathologymedicine.medical_specialtyendocrine system diseasesTumor suppressor geneAngiogenesisUbiquitin-Protein LigasesEndothelial Growth FactorsBiologyurologic and male genital diseasesmedicine.disease_causeLigaseschemistry.chemical_compoundDrug DiscoverymedicineHumansGenes Tumor SuppressorCarcinoma Renal CellGenetics (clinical)AgedLymphokinesKidneyNeovascularization PathologicVascular Endothelial Growth FactorsTumor Suppressor ProteinsProteinsMiddle Agedmedicine.diseaseKidney Neoplasmsfemale genital diseases and pregnancy complicationsGene Expression Regulation NeoplasticVascular endothelial growth factorVascular endothelial growth factor AClear cell renal cell carcinomamedicine.anatomical_structurechemistryVon Hippel-Lindau Tumor Suppressor ProteinMolecular MedicineFemaleCarcinogenesisClear cellJournal of Molecular Medicine
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The Role of Third Ventriculostomy in the Management of Obstructive Hydrocephalus

2003

Objective: Endoscopic third ventriculostomy (ETV) is an effective treatment for occlusive hydrocephalus caused by an obstruction of the CSF flow in the aqueduct or the posterior fossa. We evaluated the factors age, pathology and surgical technique on the results of the ETV. Methods: Between November 1992 and October 2000 171 ETV have been performed in 159 patients. The follow-up was evaluated in 150 patients. The age ranged from 10 days to 77 years (mean age 35 years). The hydrocephalus was caused by benign aqueductal stenosis in 77 patients, space-occupying lesions in 59, by intraventricular hemorrhages in 11, and by other causes in 3 patients. The trajectory was planned in 31 patients by …

AdultMaleVentriculostomymedicine.medical_specialtyAdolescentmedicine.medical_treatmentObstructive hydrocephalusVentriculostomyStereotaxic TechniquesCentral nervous system diseasePostoperative ComplicationsOutcome Assessment Health CaremedicineHumansChildAgedThird Ventriclemedicine.diagnostic_testbusiness.industryAge FactorsInfant NewbornEndoscopic third ventriculostomyInfantEndoscopyGeneral MedicineMiddle Agedmedicine.diseaseSurgeryHydrocephalusEndoscopyHemiparesisAqueductal stenosisChild PreschoolFemaleSurgeryNeurology (clinical)medicine.symptombusinessFollow-Up StudiesHydrocephalusmin - Minimally Invasive Neurosurgery
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[Esophageal digital videofluorography with water siphon test in the post-operative evaluation of the anti-reflux laparoscopic surgery].

2004

Background: In recent years digital videoefluorography (VFG) with water siphon test (WST) has been proposed just for diagnosing biatal bernia and/or gastroesophageal reflux. Patients and Methods: Fifteen patients undergone Laparoscopic Nissen (LN) for complicated GFRD associated to biatal bernia, were referred for VFG and WST in order to evaluate the functional results of surgery. At one- month videofluorographic control thirteen patients had just a minimal prolonged esophageal transit time hut only six of these had an early postoperative dysphagia, whereas at six montJh control the prolonged esophageal transit time was present in three patients two of which complained a very light dysphagi…

AdultMaleVideo RecordingFundoplicationWaterDysphagiaVideofuorographyRadiographic Image EnhancementHernia HiatalPostoperative ComplicationsSiphon testFluoroscopyGastroesophageal RefluxHumansNissen fundoplicationFemaleLaparoscopyDeglutition DisordersAnnali italiani di chirurgia
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Long-term comparison of corneal aberration changes after laser in situ keratomileusis: mechanical microkeratome versus femtosecond laser flap creatio…

2010

Purpose To compute and compare visual acuity, refractive outcomes, and anterior corneal aberration changes after myopic laser in situ keratomileusis (LASIK) with flap creation by a mechanical microkeratome and by a femtosecond laser. Setting Private practice refractive surgery center, Valencia, Spain. Design Comparative case series. Methods Patients were assigned to have LASIK flap creation with a mechanical microkeratome (Carriazo-Barraquer) or a femtosecond laser (IntraLase). The Visx S2 excimer laser was used for myopic ablation in all cases. Main outcome measures included uncorrected and corrected distance visual acuities and the defocus equivalent. Higher-order aberrations (HOAs) were …

AdultMaleVisual acuityCorneal Wavefront Aberrationgenetic structuresmedicine.medical_treatmentCorneal StromaKeratomileusis Laser In SituVisual AcuityKeratomileusisRefraction OcularSurgical FlapsYoung AdultPostoperative ComplicationsMicrokeratomeRefractive surgeryCorneamedicineMyopiaHumansProspective Studiesmedicine.diagnostic_testbusiness.industryLASIKCorneal TopographyMiddle AgedCorneal topographyeye diseasesSensory SystemsOphthalmologymedicine.anatomical_structurePrivate practiceOptometrySurgeryFemalesense organsmedicine.symptombusinessFollow-Up StudiesJournal of cataract and refractive surgery
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Long-term metabolic effects in patients with urinary diversion

1998

The use of intestinal segments in genitourinary reconstruction could influence vitamin metabolism and affect the skeletal bone and its mineral content in the long term. In 137 patients, serum levels of the vitamins A, B1, B2, B6, B12, D, and E and of folic acid, bile acid, and ammonia as well as levels of intracorpuscular vitamin B12 and folic acid were examined and a red blood cell count was performed. The patients were divided into three groups (or = 2 years,2 toor = 4 years, and4 years after surgery) as well as into children and adults. In addition, bone mineral density (dual-photon absorptiometry) was measured in 25 patients. Of these, 16 patients were approximately 16.8 years s/p recta…

AdultMaleVitaminmedicine.medical_specialtyTime Factorsmedicine.drug_classUrologymedicine.medical_treatmentUrinary DiversionGastroenterologychemistry.chemical_compoundPostoperative ComplicationsBone DensityIleumInternal medicinemedicineHumansVitamin B12ChildBone mineralCreatinineBile acidbusiness.industryUrinary Reservoirs ContinentMetabolic disorderUrinary diversionVitaminsmedicine.diseaseVitamin B 12EndocrinologyIntestinal AbsorptionchemistryFemaleBase excessbusinessFollow-Up StudiesWorld Journal of Urology
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Detection of oncogenic human papillomavirus genotypes on spermatozoa from male partners of infertile couples

2013

Objective To evaluate the prevalence of human papillomavirus (HPV) sperm infection and its correlation with sperm parameters in patients who attended a fertility clinic. Design Cross-sectional clinical study. Setting University-affiliated reproductive medicine clinic. Patient(s) A total of 308 male partners of couples undergoing in vitro fertilization techniques. Intervention(s) Specimens of semen were collected from all patients. Main Outcome Measure(s) Sperm parameters were evaluated according to the World Health Organization manual. The presence of HPV DNA was researched by the combined use of two HPV assays and a highly sensitive nested polymerase chain reaction assay followed by HPV ge…

AdultMaleendocrine systemmedicine.medical_specialtyGenotypeReproductive medicineSemenFertilization in VitroBiologyPolymerase Chain ReactionHuman Papillomavirus DNA TestsMale infertilityAndrologySemen qualityPredictive Value of TestsRisk FactorsGenotypemedicineHumansPapillomaviridaeIn Situ HybridizationInfertility MaleAcademic Medical CentersSperm Counturogenital systemPapillomavirus InfectionsHPV infectionvirus diseasesObstetrics and Gynecologymedicine.diseaseSpermatozoaSpermSettore MED/40 - Ginecologia E Ostetriciafemale genital diseases and pregnancy complicationsFertilityReproductive MedicineCase-Control StudiesDNA ViralSperm MotilitySperm HeadHPV infection semen parameters IVF ICSINested polymerase chain reaction
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Teprotumumab for Thyroid-Associated Ophthalmopathy

2017

Thyroid-associated ophthalmopathy, a condition commonly associated with Graves' disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns. Inhibition of the insulin-like growth factor I receptor (IGF-IR) is a new therapeutic strategy to attenuate the underlying autoimmune pathogenesis of ophthalmopathy.We conducted a multicenter, double-masked, randomized, placebo-controlled trial to determine the efficacy and safety of teprotumumab, a human monoclonal antibody inhibitor of IGF-IR, in patients with active, moderate-to-severe ophthalmopathy. A total of 88 patients were randomly assigned to r…

AdultMalemedicine.medical_specialty030209 endocrinology & metabolismDiseaseAdult; Aged; Antibodies Monoclonal; Diabetes Complications; Double-Blind Method; Exophthalmos; Female; Graves Ophthalmopathy; Humans; Hyperglycemia; Immunologic Factors; Insulin-Like Growth Factor I; Intention to Treat Analysis; Logistic Models; Male; Middle Aged; Quality of LifeAntibodies Monoclonal HumanizedPlaceboAntibodiesReceptor IGF Type 1law.inventionDiabetes ComplicationsGraves' ophthalmopathy03 medical and health sciences0302 clinical medicineDouble-Blind MethodRandomized controlled triallawInternal medicineMonoclonalmedicineClinical endpointExophthalmosHumansImmunologic FactorsInsulin-Like Growth Factor IAgedIntention-to-treat analysisTeprotumumabbusiness.industryAntibodies MonoclonalGeneral MedicineMiddle Agedmedicine.diseaseIntention to Treat AnalysisGraves OphthalmopathyLogistic ModelsHyperglycemiaMonoclonalImmunologyQuality of Life030221 ophthalmology & optometryFemalebusinessmedicine.drugNew England Journal of Medicine
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Management of intralabyrinthine schwannomas

2006

Abstract Objectives Our protocol to manage the intralabyrinthine schwannoma (ILS). Methods Retrospective chart review of 7 consecutive patients managed for ILS. Results Five patients underwent surgical removal of the lesions and none experienced significant complications or recurrent disease. One patient refused surgical treatment and was closely followed by serial MRI scans with no signs of tumor growth. One patient is presently managed conservatively due to a good hearing. Conclusions Diagnosis of ILS is based on high resolution MRI scans and should be included in the differential diagnosis of patients investigated for cochleovestibular symptoms. Treatment modality of ILS is controversial…

AdultMalemedicine.medical_specialtyAcoustic neurinomaHearing lossLabyrinth DiseasesInner ear tumorPostoperative ComplicationsVestibular schwannomaOlder patientsVertigootorhinolaryngologic diseasesRecurrent diseaseHumansMedicineIntralabyrinthine schwannomaTumor growthIntralabyrinthine schwannomaEar NeoplasmsMeniere DiseaseRetrospective Studiesbiologybusiness.industryNeuroma AcousticGeneral MedicineMiddle Agedbiology.organism_classificationMagnetic Resonance ImagingSurgeryTreatment OutcomeOtorhinolaryngologyTreatment modalityEar InnerAudiometry Pure-ToneFemaleSurgeryDifferential diagnosismedicine.symptomAudiometry SpeechbusinessAuris Nasus Larynx
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Comparative Analysis of Patients with Acute Coronary and Cerebrovascular Syndromes from the National French Hospitalization Health Care System Databa…

2010

<i>Background:</i> Nationwide evaluations of the epidemiology of acute coronary syndrome (ACS) or cerebrovascular syndrome (CVS) are scarce. We aimed to analyze nationwide French data on patients referred to hospital for either ACS or CVS. <i>Methods:</i> Using the French national hospital discharge diagnosis records, all patients hospitalized between 2005 and 2008 with a diagnosis of ACS and CVS based on the ICD-10 were identified. We analyzed vascular risk factors and early outcomes in patients with a single hospitalization for ACS or CVS or for both ACV and CVS in a 2-month time window. <i>Results:</i> 1,187,643 patients were recorded. Among these, 638…

AdultMalemedicine.medical_specialtyAcute coronary syndromePediatricsAdolescentEpidemiologyHypercholesterolemiaMyocardial Infarctionfluids and secretionsRisk FactorsInternal medicineDiabetes mellitusAtrial FibrillationEpidemiologyDiabetes MellitusmedicineHumansHospital MortalityObesityRegistriesMyocardial infarctionAcute Coronary SyndromeStrokeAgedAged 80 and overInpatientsbusiness.industryAbsolute risk reductionAtrial fibrillationMiddle Agedequipment and suppliesmedicine.diseaseStrokeCerebrovascular DisordersHypertensionMyocardial infarction complicationsFemaleFranceNeurology (clinical)businessNeuroepidemiology
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