Search results for " Cellular"
showing 10 items of 384 documents
Jahn-Teller effect in molecular electronics: quantum cellular automata
2017
The article summarizes the main results of application of the theory of the Jahn-Teller (JT) and pseudo JT effects to the description of molecular quantum dot cellular automata (QCA), a new paradigm of quantum computing. The following issues are discussed: 1) QCA as a new paradigm of quantum computing, principles and advantages; 2) molecular implementation of QCA; 3) role of the JT effect in charge trapping, encoding of binary information in the quantum cell and non-linear cell-cell response; 4) spin-switching in molecular QCA based on mixed-valence cell; 5) intervalence optical absorption in tetrameric molecular mixed-valence cell through the symmetry assisted approach to the multimode/mul…
Identification of biological markers of liver X receptor (LXR) activation at the cell surface of human monocytes.
2012
Background Liver X receptor (LXR) α and LXR β (NR1H3 and NR1H2) are oxysterol-activated nuclear receptors involved in the control of major metabolic pathways such as cholesterol homeostasis, lipogenesis, inflammation and innate immunity. Synthetic LXR agonists are currently under development and could find applications in various fields such as cardiovascular diseases, cancer, diabetes and neurodegenerative diseases. The clinical development of LXR agonists requires the identification of biological markers for pharmacodynamic studies. In this context, monocytes represent an attractive target to monitor LXR activation. They are easily accessible cells present in peripheral blood; they expres…
Is land-use change a cause of loss of pedodiversity? The case of the Mazzarrone study area, Sicily
2011
Anthropogenic soils created ex novo by land-us e change in large scale farming are, from a pedogenetic point of view, catastrophic events that bring the soils to time zero and change the natural pattern of the soilscape, remarkably, in some cases. The qu antitative aspects of pedodiversity of a soilsc ape in South-East Sicily, where some types of soils, in recent decades, have suffered a consistent reduction due to the transformations by large scale farming, are considered. The evolution of pedodiversity over a 53-year period (1955 to 2008 ) is examined using a dedicated statistical method and a space – time model based on Markov analysis and cellular autom ata in order to predict the evolu…
Simplified Probabilistic-Topologic Model for Reproducing Hillslope Rill Network Surface Runoff
2015
AbstractThis work presents a simplified probabilistic-topologic model for reproducing rill network surface runoff on a square-plane hillslope. The model requires only two parameters: the first is related to the production capacity of overland flow of the hillslope, at the initial conditions of the process, and the second depends on the sinuosity of the rill network. From a hydrological point of view, the following parameters account for the effects that essentially delineate the hydrologic response of a natural hillslope: rainfall intensity, hillslope roughness, and slope. Obviously, the reliability of the model is pending experimental validation that has only just begun. However, a prelimi…
Salvador Beltran, F., Herrando, S., Estreder, V., Ferreres, D., Adell, M. A., i Ruiz-Soler, M. (2011). A language shift simulation based on cellular …
2016
Immune-related molecole are espresse by both naive and differentiated Wharton’s jelly mesenchymal stem cells: a new avenue for cellular therapy
2012
Dendritic cells: sentinels of immunity and tolerance.
2005
The induction of effective antigen-specific T-cell immunity to pathogens without the initiation of autoimmunity has evolved as a sophisticated and highly balanced immunoregulatory mechanism. This mechanism assures the generation of antigen-specific effector cells as well as the induction and maintenance of antigen-specific tolerance to self-structures of the body. As professional antigen-presenting cells of the immune system, dendritic cells (DC) are ideally positioned throughout the entire body and equipped with a unique capability to transport antigens from the periphery to lymphoid tissues. There is growing evidence that DC, besides their well-known immunostimulatory properties, also ind…
Reversible graft versus host reaction as cause of erythrophagic splenomegaly in a child?
1977
The case history of a 9 months old infant with hepatosplenomegaly, pancytopnaenia and disturbances of clotting and cellular immune reactivity is reported. The spleen was removed and showed striking erythrophagocytosis by proliferating histiocytes, typical of "familial erythrophagocytic reticulosis" (Farquhar). A graft-versus-host reaction is discussed as a possible underlying cause. The favourable clinical course and full recovery point to an interrelation with primary hypersplenism.
T-T cell collaboration during in vivo responses to antigens coded by the peripheral and central region of the MHC.
1976
MIXED lymphocyte culture (MLC)1 has been used extensively as an in vitro model to analyse the reactivity of T cells to antigens coded by the major histocompatibility complex (MHC). When murine T responder cells are exposed in vitro to allogeneic lymphoid cells (stimulator cells) they proliferate and cytotoxic T lymphocytes (CTL) are generated2,3. Antigens coded by the central I region of the MHC are chiefly responsible for triggering proliferation4,5, whereas the target antigen of the CTL generated is either a H–2K or H–2D region or a I–A subregion gene product5–8. This dichotomy in the antigenic requirement of a MLC seems to be reflected at the level of the responding T lymphocytes. Two di…