Search results for " Complement"
showing 10 items of 753 documents
Evolution of tissue-specific keratins as deduced from novel cDNA sequences of the lungfish Protopterus aethiopicus.
2005
Lungfishes are possibly the closest extant relatives of the land vertebrates (tetrapods). We report here the cDNA and predicted amino acid sequences of 13 different keratins (ten type I and three type II) of the lungfish Protopterus aethiopicus. These keratins include the orthologs of human K8 and K18. The lungfish keratins were also identified in tissue extracts using two-dimensional polyacrylamide gel electrophoresis, keratin blot binding assays and immunoblotting. The identified keratin spots were analyzed by peptide mass fingerprinting which assigned seven sequences (inclusively Protopterus K8 and K18) to their respective protein spot. The peptide mass fingerprints also revealed the fac…
Tracing keratin evolution: catalog, expression patterns and primary structure of shark (Scyliorhinus stellaris) keratins.
1998
We have studied individual keratins of an elasmobranch, the shark Scyliorhinus stellaris (the lesser-spotted dogfish). From various shark tissues, notably skin and stomach, cytoskeletal proteins were isolated and then separated by two-dimensional polyacrylamide gel electrophoresis. Using complementary keratin blot-binding assays and immunoblotting, among these proteins we identified a variety of type I and type II keratins. According to their tissue-specific expression, we distinguished Is and IIs keratins from IE and IIE keratins ("S" and "E" from "simple epithelial" and "epidermal", respectively). Guinea pig antibodies which in immunoblots specifically labeled the entire range of identifi…
Sequence, evolution and tissue expression patterns of an epidermal type I keratin from the shark Scyliorhinus stellaris.
2004
From the shark Scyliorhinus stellaris we cloned and sequenced a cDNA encoding a novel type I keratin, termed SstK10. By MALDI-MS peptide mass fingerprinting of cytoskeletal proteins separated on polyacrylamide gels, we assigned SstK10 to a 46-kDa protein which is the major epidermal type I (“IE”) keratin in this fish and is specifically expressed in stratified epithelia. In a phylogenetic tree based on type I keratin sequences and with lamprey keratins applied as outgroup, SstK10 branches off in a rather basal position. This tree strongly supports the concept that teleost keratins and tetrapod keratins resulted from two independent gene radiation processes. The only exception is human K18 b…
The geography of the Rendiconti del Circolo Matematico di Palermo: local and international aspect
The Mathematical Circle of Palermo, founded in 1884 by 27 mathematicians all living in Palermo, became the publisher of the prestigious magazine "Rendiconti", which in thirty years became one of the leading international mathematical journals. In this talk, we will analyze the evolution of the components of the Societies and of Rendiconti towards internationalization from 1884 to 1914. Moreover, we will try to extract from the statistical data some considerations about the possible causes of the identified internationalization process
Il ruolo di Luigi Cremona nella prima formazione scientifica di Eugenio Beltrami attraverso la loro corrispondenza
In October 1862 Beltrami was appointed, before graduating, as a professor at the University of Bologna, and here he met again his friend and colleague Cremona. The correspondence between the two mathematicians clearly shows not only the intimate friendship between them, but also Cremona’s role as Beltrami’s mentor in those years. The former is indeed generous with advice, encouragement and recommendations to his friend.
The Annali di Matematica and the Rendiconti del Circolo Matematico di Palermo: two different steps in the dissemination and progress of mathematics i…
2014
The “Circolo Matematico di Palermo” and the First World War: The crisis of scientific internationalism: a view through the unedited correspondence of…
2021
Abstract In this work the situation of the “Circolo Matematico di Palermo” between 1914 and 1928 is analyzed. It will be observed that during this time the Circolo was among the few European scientific associations with German as well as French associates. During the 1930s, the nationalist politics of Fascism and above all the racial laws dealt a deadly blow to the Circolo as an international scientific association. We will use the rich correspondence in the Circolo's archives to shed some light on this. In particular, the correspondence between M. De Franchis and E. Landau and other recently found documents will figure prominently.
Historical Origins of the nine-point conic -- The Contribution of Eugenio Beltrami
2020
In this paper, we examine the evolution of a specific mathematical problem, i.e. the nine-point conic, a generalisation of the nine-point circle due to Steiner. We will follow this evolution from Steiner to the Neapolitan school (Trudi and Battaglini) and finally to the contribution of Beltrami that closed this journey, at least from a mathematical point of view (scholars of elementary geometry, in fact, will continue to resume the problem from the second half of the 19th to the beginning of the 20th century). We believe that such evolution may indicate the steady development of the mathematical methods from Euclidean metric to projective, and finally, with Beltrami, with the use of quadrat…
From the theory of “congeneric surd equations” to “Segre's bicomplex numbers”
2015
We will study the historical pathway of the emergence of Tessarines or Bicomplex numbers, from their origin as "imaginary" solutions of irrational equations, to their insertion in the context of study of the algebras of hypercomplex numbers.
Gene Expression and Epigenetic Signatures of Germ Cell-Derived Pluripotent Stem Cells and Embryonic Stem Cells
2012
Germ cell-derived Pluripotent Stem Cells (gPSCs) are pluripotent stem cells that originate from Spermatogonial Stem Cells (SSCs) of the testis. Several reports in the last few years have shown that it is possible to isolate and enrich the SSC population by different approaches and even reprogram these in vivo multipotent cells to gPSCs in vitro. As these cells could be an alternative to circumvent the ethical objections regarding the use of Embryonic Stem Cells (ESCs) for therapeutic approaches, these SSC-derived gPSCs were characterized in several studies comparatively to the gold standard of pluripotency, the ESCs. The results provide great promise that gPSCs can be of importance for pra…