Search results for " Computer vision"
showing 10 items of 352 documents
Mutations in the GLA Gene and LysoGb3: Is It Really Anderson-Fabry Disease?
2018
Anderson-Fabry disease (FD) is a rare, progressive, multisystem storage disorder caused by the partial or total deficit of the lysosomal enzyme &alpha
The intrinsic combinatorial organization and information theoretic content of a sequence are correlated to the DNA encoded nucleosome organization of…
2015
Abstract Motivation: Thanks to research spanning nearly 30 years, two major models have emerged that account for nucleosome organization in chromatin: statistical and sequence specific. The first is based on elegant, easy to compute, closed-form mathematical formulas that make no assumptions of the physical and chemical properties of the underlying DNA sequence. Moreover, they need no training on the data for their computation. The latter is based on some sequence regularities but, as opposed to the statistical model, it lacks the same type of closed-form formulas that, in this case, should be based on the DNA sequence only. Results: We contribute to close this important methodological gap …
Biological Effect of a Hybrid Anticancer Agent Based on Kinase and Histone Deacetylase Inhibitors on Triple-Negative (MDA-MB231) Breast Cancer Cells
2016
We examined the effects of the histone deacetylase inhibitor (HDACi) suberoylanilide\ud hydroxamic acid (SAHA) combined with the vascular endothelial growth factor receptor-1/2 inhibitor\ud (3Z)-5-hydroxy-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one on MDA-MB-231 breast\ud cancer cells (triple-negative) in the form of both a cocktail of the separate compounds and a chemically\ud synthesized hybrid (N-hydroxy-N'-[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-\ud 5-yl]octanediamide). Comparative flow cytometric and Western blot analyses were performed on\ud cocktail- and hybrid-treated cells to evaluate cell cycle distribution, autophagy/apoptosis modulation,\ud an…
The janus face of NKT cell function in autoimmunity and infectious diseases
2018
Natural killer T cells (NKT) are a subset of T lymphocytes bridging innate and adaptive immunity. These cells recognize self and microbial glycolipids bound to non-polymorphic and highly conserved CD1d molecules. Three NKT cell subsets, type I, II and NKT-like expressing different antigen receptors (TCR) were described and TCR activation promotes intracellular events leading to specific functional activities. NKT can exhibit different functions depending on the secretion of soluble molecules and the interaction with other cell types. NKT cells act as regulatory cells in the defence against infections but, on the other hand, their effector functions can be involved in the pathogenesis of sev…
Automatic detection and measurement of nuchal translucency.
2017
In this paper we propose a new methodology to support the physician both to identify automatically the nuchal region and to obtain a correct thickness measurement of the nuchal translucency. The thickness of the nuchal translucency is one of the main markers for screening of chromosomal defects such as trisomy 13, 18 and 21. Its measurement is performed during ultrasound scanning in the first trimester of pregnancy. The proposed methodology is mainly based on wavelet and multi resolution analysis. The performance of our method was analysed on 382 random frames, representing mid-sagittal sections, uniformly extracted from real clinical ultrasound videos of 12 patients. According to the groun…
PERFORMANCE EVALUATIONS OF 3D WEB-SERVICES AND OPEN-SOURCE SOFTWARE FOR DIGITAL MODELING OF ARCHAEOLOGICAL FINDS
2016
The Structure From Motion (SFM) algorithms derived from Computer Vision community make image-based techniques a competitive and user friendly approach to obtain 3D information of real objects. These algorithms have been implemented in many 3D web-services and open-source software to develop free instruments for the reconstruction of very detailed 3D digital models. Their use is becoming very common above all in archaeological studies but their potentiality for metric application has not been tested at all. The aim of the work is to investigate the quality and the accuracy of 3D models obtained through 3D web-services and SFM open-source software. Different tests have been performed using so…
Vision metrology and Structure from Motion for archaeological heritage 3D reconstruction: A Case Study of various Roman mosaics
2017
<p class="Abstract">Vision metrology and computer vision can be successfully used for archaeological heritage 3D reconstruction in very high precision 3D measurement projects. Of those archaeological objects requiring very accurate measurements (&lt;1 mm), ancient mosaics comprise some of the most important. The aim of this paper is to assess the photogrammetric/computer vision approach in a vision metrology context as part of a 3D mosaics survey. In order to evaluate the optimal photogrammetric/computer vision workflow in this work, three different surveys were performed on three mosaics of different sizes and locations. Two of these are stored at the <em>Antonino Salinas&l…
Designing the 5G network infrastructure: a flexible and reconfigurable architecture based on context and content information
2018
5G networks will have to offer extremely high volumes of content, compared to those of today’s. Moreover, they will have to support heterogeneous traffics, including machine-to-machine, generated by a massive volume of Internet-of-Things devices. Traffic demands will be variable in time and space. In this work, we argue that all this can be achieved in a cost-effective way if the network is flexible and reconfigurable. We present the Flex5Gware network architecture, designed to meet the above requirements. Moreover, we discuss the links between flexibility and reconfigurability, on the one side, and context awareness and content awareness, on the other; we show how two of the building…
An architecture for autonomous agents exploiting conceptual representations
1998
An architecture for autonomous agents is proposed that integrates the functional and the behavioral approaches to robotics. The integration is based on the introduction of a conceptual level, linking together a subconceptual, behavioral, level, and a linguistic level, encompassing symbolic representation and data processing. The proposed architecture is described with reference to an experimental setup, in which the robot task is that of building a significant description of its working environment. © 1998 Elsevier Science B.V. All rights reserved.
Data-based modeling of vehicle crash using adaptive neural-fuzzy inference system
2014
Vehicle crashes are considered to be events that are extremely complex to be analyzed from the mathematical point of view. In order to establish a mathematical model of a vehicle crash, one needs to consider various areas of research. For this reason, to simplify the analysis and improve the modeling process, in this paper, a novel adaptive neurofuzzy inference system (ANFIS-based) approach to reconstruct kinematics of colliding vehicles is presented. A typical five-layered ANFIS structure is trained to reproduce kinematics (acceleration, velocity, and displacement) of a vehicle involved in an oblique barrier collision. Subsequently, the same ANFIS structure is applied to simulate different…