Search results for " Coronaviru"

showing 10 items of 730 documents

Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM …

2020

Abstract Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pre…

COVID-19 VaccineInfectious Disease TransmissionPerinatal DeathAbortionClinical Laboratory TechniqueMiscarriageCohort Studies0302 clinical medicineCOVID-19 TestingPregnancyRisk Factors3123 Gynaecology and paediatricsSecondary analysisPerinatal medicineAbortion SpontaneouMedicineVertical030212 general & internal medicineViralPregnancy Complications Infectiouscoronavirus; perinatal morbidity; perinatal mortality; covid-19Coronavirus; perinatal morbidity; perinatal mortality; Abortion Spontaneous; COVID-19; COVID-19 Testing; COVID-19 Vaccines; Clinical Laboratory Techniques; Cohort Studies; Coronavirus Infections; Female; Gestational Age; Humans; Infant Newborn; Infant Premature; Infectious Disease Transmission Vertical; Pandemics; Pneumonia Viral; Pregnancy; Pregnancy Complications Infectious; Pregnancy Outcome; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; SARS-CoV-2; Betacoronavirus; Fetal Death; Perinatal Deathperinatal morbidity030219 obstetrics & reproductive medicineObstetricsReverse Transcriptase Polymerase Chain ReactionInfectiousPregnancy OutcomeGestational ageObstetrics and Gynecology3. Good healthSettore MED/40perinatal mortalityGestationFemaleCoronavirus InfectionsInfant PrematureHumanmedicine.medical_specialtyCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)CoronaviruPneumonia ViralSocio-culturaleGestational AgeIntrauterine deviceCoronavirus; perinatal morbidity; perinatal mortality03 medical and health sciencesBetacoronavirusPARVOVIRUS B19 INFECTIONCoronavirus perinatal morbidity perinatal mortalityHumansAdverse effectPrematurePandemicsFetal DeathPregnancyFetusBetacoronaviruPandemicCoronavirus Infectionbusiness.industryClinical Laboratory TechniquesSARS-CoV-2Risk FactorSpontaneousMORTALITYInfant NewbornAbortionCOVID-19InfantOdds ratioPneumoniamedicine.diseaseNewbornInfectious Disease Transmission VerticalAbortion SpontaneousPregnancy ComplicationsCoronavirusPediatrics Perinatology and Child HealthPregnancy Complications InfectiouCohort StudiebusinessCoronavirus; perinatal mortality; perinatal morbidityJournal of perinatal medicine
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Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pande…

2020

Background Starting December 2019, mankind faced an unprecedented enemy, the COVID-19 virus. The world convened in international efforts, experiences and technologies in order to fight the emerging pandemic. Isolation, hygiene measure, diagnosis, and treatment are the most efficient ways of prevention and intervention nowadays. The health organizations and global care systems screened the available resources and offered recommendations of approved and proposed medications. However, the search for a specific selective therapy or vaccine against COVID-19 remains a challenge. Methods A literature search was performed for the screening of natural and derived bio-active compounds which showed po…

COVID-19 VaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Drug Evaluation PreclinicalPharmaceutical ScienceAntiviral AgentsArticle03 medical and health scienceschemistry.chemical_compoundClinical trials0302 clinical medicineTocilizumabChloroquineDrug DiscoveryPandemicmedicineHumansAntiviralPandemics030304 developmental biologyPharmacologyBiological ProductsClinical Trials as TopicNatural products0303 health sciencesProtectionMolecular StructureTraditional medicineSARS-CoV-2business.industryCOVID-19LycorineFingolimodCOVID-19 Drug TreatmentClinical trialConessineComplementary and alternative medicinechemistry030220 oncology & carcinogenesisMolecular MedicinePatentPlant Preparationsbusinessmedicine.drugPhytomedicine
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First detection of SARS-CoV-2 A.23.1 sub-lineage in migrants arriving to Italy via the Mediterranean Sea and public health implications

2021

COVID-19 Mediterranean sea Migrants Molecular surveillance NGS Phylogeny analysis Public health SARS-CoV-2 Vaccination programs2019-20 coronavirus outbreakmedicine.medical_specialtyLineage (genetic)Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Vaccination programsMigrantsArticlePhylogeny analysisMediterranean seamedicineHumansPhylogenyTransients and MigrantsPublic healthSARS-CoV-2Public healthPublic Health Environmental and Occupational HealthCOVID-19VirologyInfectious DiseasesGeographyItalyMolecular surveillanceNGSMediterranean seaTravel Medicine and Infectious Disease
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Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection

2021

WOS:000613461600006 PubMed ID: 32926494 Objectives To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection. Methods This was a multinational retrospective cohort study including women with a singleton pregnancy and laboratory-confirmed SARS-CoV-2 infection, conducted in 72 centers in 22 different countries in Europe, the USA, South America, Asia and Australia, between 1 February 2020 and 30 April 2020. Confirmed SARS-CoV-2 infection was defined as a positive result on real-time reverse-transcription polymerase chain reaction (RT-PCR) assay of nasopharyngeal swab specimens. The primary outcome was a composite measure of maternal mortality and morbidity…

COVID19medicine.medical_treatmentcoronavirus; COVID-19; infection; pregnancy; SARS-CoV-2Abortioninfectious diseaseslaw.inventionCohort Studies0302 clinical medicinelaw3123 Gynaecology and paediatricsPregnancyObstetrics and Gynaecology030212 general & internal medicinePregnancy Complications Infectious030219 obstetrics & reproductive medicineRadiological and Ultrasound TechnologyTransmission (medicine)ObstetricsPregnancy OutcomeObstetrics and GynecologyCOVID19; Coronavirus; SARS-COV-2; infection; pregnancy.General MedicineDisease 2019 Covid-19Intensive care unit3. Good healthHospitalizationIntensive Care UnitsMaternal MortalitySettore MED/40Radiology Nuclear Medicine and imagingGestationFemalepregnancycoronavirus Pandemics Pregnancy Pregnancy Complications Infectious Pregnancy Outcome Respiration Artificial Retrospective Studies SARS-CoV-2 COVID-19 Infant Newborn Intensive Care UnitsMaternal MortalityInfectionCohort studyAdultmedicine.medical_specialtyCOVID-19; SARS-CoV-2; coronavirus; infection; pregnancyNO03 medical and health sciencesmedicineHumansRadiology Nuclear Medicine and imagingPandemicsRetrospective StudiesMechanical ventilationPregnancybusiness.industrySARS-CoV-2Infant NewbornInfantCOVID-19Retrospective cohort studymedicine.diseaseRespiration ArtificialinfectionCoronaviruscoronaviruReproductive MedicinebusinessCOVID19; Coronavirus; SARS-COV-2; infection; pregnancy
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COVID-19 infection in cancer patients: what has been the contribution of Associazione Italiana Oncologia Medica (AIOM) to oncological care since the …

2021

High mortality rates in elderly patients or in those with underlying chronic illnesses and/or a compromised immune system is a peculiar feature of COVID-19 infection. The possible coexistence of a cancer and COVID-19 infection in the same individual prompted concerns regarding their synergistic effect on prognosis. In order to balance patients’ needs with the risks related to the infection, the question oncologists have asked from the beginning of the first wave of the pandemic has been: ‘how can we deal with COVID-19 infection in cancer patients?’ In pursuing its mission, the Associazione Italiana Oncologia Medica (AIOM) has made every possible effort to support cancer patients, health car…

Cancer Research2019-20 coronavirus outbreakmedicine.medical_specialtyCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)FAVO Federazione delle Associazioni di Volontariato in OncologiaReviewWHO World Health OrganizationCIPOMO Italian College of Primary Hospital Medical OncologistsSICO Società Italiana di Chirurgia OncologicaMedicalNeoplasmsHealth carePandemicMedicinecancerCentral Venous CathetersHumansFNOPI Federazione Nazionale Ordini Professioni InfermieristicheSocieties MedicalAIRO Associazione Italiana Radioterapia e Oncologia clinicaOncologistsClinical Trials as Topictreatmentbusiness.industryHigh mortalityAIOM Associazione Italiana di Oncologia medicaCancerNeoplasms therapyAIOM; cancer; COVID-19; treatment; vaccination; Central Venous Catheters; Clinical Trials as Topic; Humans; Influenza Vaccines; Oncologists; Practice Guidelines as Topic; COVID-19; COVID-19 Vaccines; Neoplasms; Societies MedicalCOVID-19medicine.diseasevaccinationCOMU College of University Medical OncologistsOncologyInfluenza VaccinesFamily medicineFOCE ConFederazione degli Oncologi Cardiologi e EmatologiPractice Guidelines as TopicESMO European Society for Medical OncologybusinessSocietiesSIPO Società Italiana di Psico-OncologiaAIOMESMO open
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Management of patients with chronic lymphocytic leukemia during the SARS‑CoV‑2 pandemic (Review)

2021

Oncohematological patients are prone to develop infections due to immunosuppression caused by the disease and chemo-immunotherapy. The aim of this review was to outline the details of the management of patients with chronic lymphocytic leukemia (CLL) during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Patients with CLL often exhibit inadequate humoral and cellular immune responses to various infections and vaccinations. Patients under the ‘watch and wait’ strategy have a lower risk of infections, including with SARS-CoV-2, compared with those undergoing therapeutic interventions, but they still have a higher risk than age-matched controls. Patients with CLL hav…

Cancer ResearchChronic lymphocytic leukemiamedicine.medical_treatmentReviewDiseaseLower riskHypogammaglobulinemiachemistry.chemical_compoundibrutinibhemic and lymphatic diseasesMedicinevenetoclaxbusiness.industryVenetoclaxcoronavirus disease-2019Antibody titerImmunosuppressionmedicine.diseaseOncologychemistryIbrutinibImmunologychronic lymphocytic leukemiamonoclonal antibodiesbusinesssevere acute respiratory syndrome coronavirus 2Oncology Letters
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Risk of coronavirus disease 2019 in patients treated for cancer: An immune response–based hypothesis

2020

Cancer ResearchCoronavirus disease 2019 (COVID-19)Pneumonia Viralhumans; betacoronavirus; coronavirus; coronavirus infections; pandemics; pneumonia; viralcoronaviruspandemicsmedicine.disease_causeArticlecoronavirus infectionsImmune systemPandemicmedicinepneumoniaIn patienthumansCoronavirusbiologySARS-CoV-2business.industryCOVID-19Cancerbiology.organism_classificationmedicine.diseasebetacoronavirusPneumoniaOncologyImmunologybusinessBetacoronavirusviralEuropean Journal of Cancer
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Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study

2020

Background The aims of this study were to provide data on the safety of head and neck cancer surgery currently being undertaken during the coronavirus disease 2019 (COVID-19) pandemic. Methods This international, observational cohort study comprised 1137 consecutive patients with head and neck cancer undergoing primary surgery with curative intent in 26 countries. Factors associated with severe pulmonary complications in COVID-19-positive patients and infections in the surgical team were determined by univariate analysis. Results Among the 1137 patients, the commonest sites were the oral cavity (38%) and the thyroid (21%). For oropharynx and larynx tumors, nonsurgical therapy was favored in…

Cancer ResearchInfectious Disease TransmissionSettore MED/29 - CHIRURGIA MAXILLOFACCIALEInternational CooperationSettore MED/19 - Chirurgia Plasticacoronavirusmedicine.disease_causePatient-to-Professionalsurgery0302 clinical medicine80 and over030212 general & internal medicineCoronavirusAged 80 and overUnivariate analysisCOMPLICATIONSOUTCOMESIncidence (epidemiology)Middle AgedOncologyHead and Neck Neoplasms030220 oncology & carcinogenesiscoronavirus disease 2019 (COVID-19)Cohort studyAdultmedicine.medical_specialtyInfectious Disease Transmission Patient-to-ProfessionalCritical Care03 medical and health sciencesPatient safetyYoung AdultSettore MED/28 - Malattie OdontostomatologichemedicineHumansReconstructive Surgical Proceduressevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicsPersonal Protective EquipmentAgedNeoplasm StagingSurgeonsSurgical teambusiness.industryHead and neck cancerCancerCOVID-19Plastic Surgery ProceduresCAREmedicine.disease3126 Surgery anesthesiology intensive care radiologySurgerycoronavirucoronavirus; coronavirus disease 2019 (COVID-19); head and neck cancer; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); surgeryhead and neck cancerbusiness
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Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients.

2021

Abstract In the midst of the COVID-19 pandemic, different vaccines in front of SARS-CoV-2 have been approved and administered in different vulnerable populations. As patients with cancer were excluded from pivotal trials of vaccination, little is known on their immunogenic response to these vaccines, particularly in patients with severely impaired immune system. In response to that uncertainty, the Spanish Society of Hematology and Hemotherapy launched an initiative aimed to provide recommendations for vaccination of the main hematological conditions. This document is based on the available information on COVID-19 outcomes, prior knowledge on vaccination in hematological patients, recent pu…

Cancer Researchmedicine.medical_specialtyCOVID-19 VaccinesConsensusCoronavirus disease 2019 (COVID-19)myeloproliferative neoplasmSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)lymphomaReviewstem cell transplantationCOVID-19 SARS-CoV-2 vaccine acute leukemia allogeneic stem cell transplantation lymphoma myelodisplastic syndrome myeloproliferative neoplasm onco-hematology stem cell transplantation vaccination consensusallogeneic stem cell transplantationSARS-CoV-2 vaccineInternal medicinePandemicmedicineHemotherapyHumansIn patientacute leukemiaIntensive care medicineExpert TestimonyPandemicsonco-hematologyHematologySARS-CoV-2business.industryVaccinationCOVID-19Expert consensusHematologyVaccinationvaccination consensusOncologymyelodisplastic syndromebusiness
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Reactions and countermeasures of medical oncologists towards the incoming COVID-19 pandemic: A whatsapp messenger-based report from the Italian colle…

2020

Background This descriptive, unplanned investigation has been undertaken to report reactions, attitudes and countermeasures which have been put in place and implemented by medical oncology units facing the COVID-19 outbreak in Southern Italy. Materials and methods Data have been retrospectively obtained from the time-related analysis of conversations via a WhatsApp messenger-based group chat between the medical directors belonging to the Italian College of Medical Oncology Directors. Overall number, intensity and time trend of conversations related to reactions during the 4 weeks of observation related to the crucial events which occurred between 24 February and 28 March, 2020 2020 are incl…

Cancer Researchmedicine.medical_specialtyGovernmentSentimental analysiCOVID-19 outbreakCoronavirus disease 2019 (COVID-19)Reactionbusiness.industryMedical oncologistSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ResearchSentiment analysisSentimental analysisWhatsApp messengerOncologyAction takenFamily medicinePandemicEpidemic spreadReactionsMedicinebusinessRaw dataMedical oncologistsHealthcare system
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