Search results for " DEP"
showing 10 items of 5568 documents
Una aproximación empírica desde el modelo canadiense de desempeño ocupacional: calidad de vida en profesionales de la red de centros para personas co…
2017
TITULO UNA APROXIMACIÓN EMPÍRICA DESDE EL MODELO CANADIENSE DE DESEMPEÑO OCUPACIONAL: CALIDAD DE VIDA EN PROFESIONALES DE LA RED DE CENTROS PARA PERSONAS CON DIVERSIDAD FUNCIONAL DE LA PROVINCIA DE CÓRDOBA Tesis Doctoral presentada por: D.ª Lidia Revuelto Palma Dirigida por: Dra. Amparo Oliver Germes y Dr. Salvador Simó Algado Programa de Doctorado en Atención Socio-Sanitaria a la Dependencia. MARCO TEÓRICO En la clínica se puede observar la importancia del trabajador a la hora de que se produzcan cambios reales, tanto en la personas usuarias o clientes como en el contexto social. Esta importancia se ve, por un lado, positivamente cuando la persona tiene esperanza de cambio y que forma part…
The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.
2021
Since the approval of the first monoclonal antibody (mAb) in 1986, a huge effort has been made to guarantee safety and efficacy of therapeutic mAbs. As of July 2021, 118 mAbs are approved for the European market for a broad range of clinical indications. In order to ensure clinical efficacy and safety aspects, (pre-)clinical experimental approaches evaluate the respective modes of action (MoA). In addition to antigen-specificity including binding affinity and -avidity, MoA comprise Fc-mediated effector functions such as antibody dependent cellular cytotoxicity (ADCC) and the closely related antibody dependent cellular phagocytosis (ADCP). For this reason, a variety of cell-based assays have…
Late Pleistocene vertebrate - bearing deposits at San Teodoro Cave (North-Eastern Sicily): Preliminary data on faunal diversification and chronology
2008
Abstract This paper deals with the chronology and the possible correlations among levels of different excavated areas in the Pleistocene vertebrate-bearing deposits at the large San Teodoro Cave (North-Eastern Sicily). Two trenches have been excavated along the eastern side of the cave, located at a distance from the entrance, respectively, of 8 m ( α trench) and 28 m ( β trench) and at different depths. Lithological features, biometrical data from small mammals and ecological data from molluscs point to similar environmental conditions for the α trench deposits and those located along the eastern wall of the cave in the eastern part of the β trench. The same evidence, and the taphonomic fe…
Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre Auger Observatory
2017
We report a multi-resolution search for anisotropies in the arrival directions of cosmic rays detected at the Pierre Auger Observatory with local zenith angles up to $80^\circ$ and energies in excess of 4 EeV ($4 \times 10^{18}$ eV). This search is conducted by measuring the angular power spectrum and performing a needlet wavelet analysis in two independent energy ranges. Both analyses are complementary since the angular power spectrum achieves a better performance in identifying large-scale patterns while the needlet wavelet analysis, considering the parameters used in this work, presents a higher efficiency in detecting smaller-scale anisotropies, potentially providing directional informa…
The effect of transient visual deprivation on motor cortical excitability and motor learning : a pilot study
2016
Castro, Fabio, 2015. The Effect of Transient Visual Deprivation on Motor Cortical Excitability and Motor Learning. University of Jyväskylä, Department of Biology of Physical Activity, Master Thesis in Applied Biomechanics. 86 pp. We devised an experimental protocol to test the hypothesis that if the performer poses attention on the proprioceptive signals, in the form of awareness of the body in space, this could increase the corticospinal excitability and the overall performance. 10 right-handed volunteers were randomly assigned to either a group performing a skill training blindfolded (BLIND) or in normal (NORM) condition. The intervention included a visuomotor task-related skill training …
Motivation for participation in rehab therapy and stress-coping styles in alcohol dependent women and men = Motywacja do udziału w terapii i style ra…
2020
Wprowadzenie: Przedstawiono przegląd literatury z zakresu stylów radzenia sobie ze stresem i motywacji do uczestnictwa w terapii w grupie kobiet i mężczyzn uzależnionych od alkoholu. Wywnioskowano, że dotychczasowe dane empirycznie pozwalają na zaobserwowanie zróżnicowania ze względu na płeć, ale nie umożliwiają stworzenia jednoznacznych modeli w zakresie motywacji i radzenia sobie ze stresem przez kobiety i mężczyzn. Materiał i metody: W badaniu wzięło udział 90 ochotników (33 K i 57 M) w wieku od 22 do 70 lat (M = 43,70; SD = 11,26), uczęszczających na terapię uzależnień (M = 7,97 miesięcy; SD = 5,76) do ośrodka leczenia uzależnień na Górnym Śląsku. Respondenci wypełnili metryczkę, Kwesti…
El fenómeno senderista en España. Análisis por un panel de expertos
2014
El fenómeno senderista en España. Análisis por un panel de expertos. El senderismo se ha convertido en una de las actividades físico-recreativas más importantes de nuestra sociedad. Los enfoques de práctica superan las motivaciones deportivas para incorporar objetivos turísticos, de calidad de vida, de movilidad no motorizada o del desarrollo rural, por citar algunos ejemplos. Por otra parte, el senderismo admite actividades afines (excursionismo, caminata, trekking, paseo,…) y coexiste perfectamente con otras prácticas complementarias (carreras de montaña, vías ferratas, Btt, equitación,…) que le convierten en un verdadero fenómeno social. Frente una actividad de tal envergadura y transcen…
On multivalued weakly Picard operators in partial Hausdorff metric spaces
2015
We discuss multivalued weakly Picard operators on partial Hausdorff metric spaces. First, we obtain Kikkawa-Suzuki type fixed point theorems for a new type of generalized contractive conditions. Then, we prove data dependence of a fixed points set theorem. Finally, we present sufficient conditions for well-posedness of a fixed point problem. Our results generalize, complement and extend classical theorems in metric and partial metric spaces.
Neridronate prevents bone loss in patients receiving androgen deprivation therapy for prostate cancer.
2004
Today, androgen deprivation therapy is a cornerstone of treatment for advanced prostate cancer, although it presents important complications such as osteoporosis. Neridronate, a relatively new bisphosphonate, is able to prevent bone loss in patients with prostate cancer during androgen ablation. Introduction: Androgen-deprivation therapy (ADT) is a cornerstone of treatment for advanced prostate cancer. This therapy has iatrogenic complications, such as osteoporosis. The aim of our study was to evaluate the efficacy of neridronate, a relatively new bisphosphonate, to prevent bone loss during androgen ablation. Materials and Methods: Forty-eight osteoporotic patients with prostate cancer, tre…
Bone mineral density, structure, distribution and strength in men with prostate cancer treated with androgen deprivation therapy
2019
Androgen deprivation therapy (ADT) improves survival in men with advanced prostate cancer (PCa), but has been associated with compromised skeletal health and increased fracture risk. However, limited previous research has investigated determinants of bone strength beyond DXA-derived areal bone mineral density (aBMD) in this population group. The aim of this cross-sectional study was to investigate the effects of ADT in men with PCa on BMD, bone structure, estimates of whole bone strength and cortical bone distribution. A total of 70 ADT-treated men, 52 PCa controls and 70 healthy controls had DXA lumbar spine and proximal femur aBMD and pQCT distal (4%) and proximal (66%) tibia and radius c…