Search results for " DFT."

showing 10 items of 87 documents

Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity.

2016

Indexación: Web of Science Theoretical reactivity indices based on the conceptual Density Functional Theory (DFT) have become a powerful tool for the semiquantitative study of organic reactivity. A large number of reactivity indices have been proposed in the literature. Herein, global quantities like the electronic chemical potential μ, the electrophilicity ω and the nucleophilicity N indices, and local condensed indices like the electrophilic and nucleophilic Parr functions, as the most relevant indices for the study of organic reactivity, are discussed. http://www.mdpi.com/1420-3049/21/6/748

Chemical PhenomenaNucleophilicityChemistry OrganicPharmaceutical ScienceElectronsnucleophilicityReview010402 general chemistry01 natural sciencesreactivity indicesAnalytical ChemistryMolecular electron density theorylcsh:QD241-441Reactivity indicesNucleophilelcsh:Organic chemistryconceptual DFTParr functionsComputational chemistryDrug DiscoveryOrganic chemistryReactivity (chemistry)Physical and Theoretical ChemistryElectrophilicity010405 organic chemistryChemistryOrganic Chemistrymolecular electron density theory0104 chemical sciencesChemistry (miscellaneous)Conceptual DFTElectrophileMolecular MedicineQuantum TheoryDensity functional theoryelectrophilicityMolecules (Basel, Switzerland)
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Computational Study on Cesium Azide Trapped in a Cyclopeptidic Tubular Structure

2008

The structures and the electronic properties of host-guest complexes formed by a cyclopeptidic tubular aggregate and the species CsN3, CS2(N-3)(2), and CS2N6 have been investigated by means of density functional theory. Taking advantage of the azide property to act as a bridge ligand between two or more metal cations, it may be possible to trap N-3(-) ions inside a confined space. This could be important for the preparation of polynitrogen molecules N-n. Results show that there are significant attractive interactions between the azide ion and the cavity walls, which make the ion stay inside the inner empty space of the cyclopeptidic aggregate. The confinement of the species CS2(N-3)(2) forc…

ChemistryLigandNanotechnologyComputer Science ApplicationsIonMetalchemistry.chemical_compoundChemical physicsvisual_artvisual_art.visual_art_mediumMoleculeDensity functional theoryAzidePhysical and Theoretical ChemistryConfined spaceCavity wallAzides DFT tubular aggregateJournal of Chemical Theory and Computation
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Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences

2021

The specific recognition of AT-rich DNA sequences opens up the door to promising diagnostic and/or therapeutic strategies against gene-related diseases. Here, we demonstrate that amphiphilic PtII complexes of the type [Pt(dmba)(N∧N)]NO3 (dmba = N,N-dimethylbenzylamine-κN, κC; N∧N = dpq (3), dppz (4), and dppn (5)) recognize AT-rich oligonucleotides over other types of DNA, RNA, and model proteins. The crystal structure of 4 shows the presence of significant π-stacking interactions and a distorted coordination sphere of the d8 PtII atom. Complex 5, containing the largest π-conjugated ligand, forms supramolecular assemblies at high concentrations under aqueous environment. However, its aggreg…

Coordination sphereOrganoplatinum CompoundsStereochemistrySupramolecular chemistryDMBAElectrophoretic Mobility Shift Assay010402 general chemistryCrystallography X-RayLigands01 natural sciencesArticleInorganic Chemistrychemistry.chemical_compoundCoordination ComplexesHumansPhysical and Theoretical ChemistryDNA • light-switch • platinum • pseudo-tetrahedral • antitumor agent • DFTOrganoplatinumGel electrophoresisMolecular Structure010405 organic chemistryChemistryOligonucleotideLigandSpectrum AnalysisStereoisomerismDNAIntercalating Agents0104 chemical sciencesA549 CellsSettore CHIM/03 - Chimica Generale E InorganicaDNA
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Karplus-Type Dependence of Vicinal119Sn-13C and119Sn-1H Spin-Spin Couplings in Organotin(IV) Derivatives: A DFT Study

2009

The empirical Karplus-type dependence of (3)J((119)Sn,(13)C) and (3)J((119)Sn,(1)H) couplings in organotin(IV) derivatives has been computationally validated by DFT methods both at the nonrelativistic and scalar ZORA relativistic level. A preliminary calibration of the computational protocols, by comparing experimental and calculated couplings for a Set Of Suitable rigid molecules, revealed their high predictive power: in particular, relativistic results for (3)J((119)Sn,(13)C) have a mean absolute error of just above 2 Hz, over a range of values up to about 70 Hz. The latter protocol has then been used to study in detail the influence of substituents and multiple paths connecting the coupl…

Coupling constantChemistryKarplus equationOrganic ChemistryCarbon-13Scalar (mathematics)Relativistic effectsNuclear magnetic resonance spectroscopyRelativistic effects DFT NMR spectroscopy tinMolecular physicsDensity functional calculations; NMR spectroscopy; Relativistic effects; TinDensity functional calculationsNMR spectroscopyNuclear magnetic resonanceTinMoleculePhysical and Theoretical ChemistryRelativistic quantum chemistryorganotinVicinalSpin-½European Journal of Organic Chemistry
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A DFT study of the Karplus-type dependence of vicinal 3J(Sn-C-X- C), X=N,O,S, in organotin(iv) compounds: Application to conformationally flexible sy…

2010

ZORA relativistic and non-relativistic DFT protocols have been used to investigate vicinal coupling constants, (3)J(Sn-C-X-C), in several organotin(iv) compounds, with particular emphasis on cyclic alpha-aminoorganostannanes. The dependence of the coupling constant on the heteroatom X (X = N,O,S) in the coupling path, and, for X = N, its substituents, has been studied in detail. The electron-withdrawing strength of the N-substituents has been found to strongly affect the magnitude and shape of the Karplus-type curve. The results obtained for the simple model systems, having no or little conformational flexibility, have helped in rationalizing the data concerning real flexible cyclic systems…

Coupling constantCouplingeducation.field_of_study119Tin NMR vicinal coupling constants DFTChemistryOrganic ChemistryHeteroatomPopulationType (model theory)BiochemistryComputational chemistryPhysical and Theoretical ChemistryeducationConformational isomerismVicinal
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Relativistic DFT Calculation of (119)Sn Chemical Shifts and Coupling Constants in Tin Compounds.

2006

The nuclear shielding and spin-spin coupling constants of (119)Sn in stannane, tetramethylstannane, methyltin halides Me4-nSnXn (X = Cl, Br, I; n = 1-3), tin halides, and some stannyl cations have been investigated computationally by DFT methods and Slater all-electron basis sets, including relativistic effects by means of the zeroth order regular approximation (ZORA) method up to spin-orbit coupling. Calculated (119)Sn chemical shifts generally correlate well with experimental values, except when several heavy halogen atoms, especially iodine, are bound to tin. In such cases, calculated chemical shifts are almost constant at the scalar (spin-free) ZORA level; only at the spin-orbit level i…

Coupling constantchemistry.chemical_classificationNMR spectroscopy; computational chemistry; tin compounds; tin-119Chemical shifttin compoundsHalidechemistry.chemical_elementOrganotin(IV) NMR DFT coupling constantstin-119Stannanecomputational chemistryComputer Science Applicationschemistry.chemical_compoundNMR spectroscopychemistryComputational chemistryHalogenPhysics::Atomic and Molecular ClustersPhysics::Chemical PhysicsPhysical and Theoretical ChemistryTinRelativistic quantum chemistryAlkylJournal of chemical theory and computation
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A DFT study of the vicinal 3J(119Sn,13C) and 3J(119Sn,1H) coupling constants in trimethyl- and chlorodimethyl-stannyl propanoates.

2013

Abstract We have tested the performance of DFT protocols, both at the Scalar relativistic ZORA and non-relativistic level of theory, for the calculation of the 3 J( 119 Sn, 13 C) and 3 J( 119 Sn, 1 H) vicinal couplings for a series of flexible organotin(IV) derivatives with formula XMe2SnCHRCHR′COOMe (X = Me, Cl; R, R′ = Me, Ph). A satisfactory agreement between experimental and calculated vicinal couplings has been obtained by taking into account the conformational behaviour of the compounds investigated. The protocols used, mainly the relativistic one, were found to give a correct picture of the populations and a sufficiently high overall performance in calculating the vicinal couplings, …

Coupling constantheteronuclear NMR spectroscopySeries (mathematics)ChemistryOrganoTin(IV) 119Sn NMR 119Sn couplings Karplus DFT Relativistic ZORAOrganic ChemistryScalar (mathematics)heteronuclear NMR spectroscopy; DFT calculations; tin compoundstin compoundsDFT calculationsBiochemistryInorganic ChemistryComputational chemistrySettore CHIM/03 - Chimica Generale E InorganicaMaterials ChemistryOverall performancePhysical and Theoretical ChemistryVicinal
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Elektrónová a pásová štruktúra CuMnAs študovaná optickou a fotoemissinou spektroskopiou

2017

Tetragonal phase of CuMnAs progressively appears as one of the key materials for antiferromagnetic spintronics due to efficient current-induced spin-orbit torques whose existence can be directly inferred from crystal symmetry. Theoretical understanding of spintronic phenomena in this material, however, relies on the detailed knowledge of electronic structure (band structure and corresponding wave functions) which has so far been tested only to a limited extent. We show that AC permittivity (obtained from ellipsometry) and UV photoelectron spectra agree with density functional calculations. Together with the x-ray diffraction and precession electron diffraction tomography, our analysis confi…

DiffractionCondensed Matter - Materials ScienceMaterials scienceSpintronicsCondensed matter physicsPhotoemission spectroscopyMaterials Science (cond-mat.mtrl-sci)FOS: Physical sciencesspintronics DFT photoemission optical properties CuMnAs02 engineering and technologyCrystal structureElectronic structure021001 nanoscience & nanotechnology01 natural sciences3. Good healthTetragonal crystal systemCondensed Matter::Materials ScienceSpintronika DFT fotoemissia optické vlastnosti CuMnAs0103 physical sciencesPrecession electron diffraction010306 general physics0210 nano-technologyElectronic band structure
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Molecular Electron Density Theory: A Modern View of Reactivity in Organic Chemistry

2016

A new theory for the study of the reactivity in Organic Chemistry, named Molecular Electron Density Theory (MEDT), is proposed herein. MEDT is based on the idea that while the electron density distribution at the ground state is responsible for physical and chemical molecular properties, as proposed by the Density Functional Theory (DFT), the capability for changes in electron density is responsible for molecular reactivity. Within MEDT, the reactivity in Organic Chemistry is studied through a rigorous quantum chemical analysis of the changes of the electron density as well as the energies associated with these changes along the reaction path in order to understand experimental outcomes. St…

Electron densitymolecular mechanismsChemistry OrganicPharmaceutical ScienceElectronsElectron010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Electron density distributionlcsh:Organic chemistryComputational chemistryDrug DiscoveryDFT reactivity indicesNon-covalent interactionsOrganic chemistryReactivity (chemistry)Physical and Theoretical Chemistryelectron densityQuantum chemicalchemistry.chemical_classification010405 organic chemistryOrganic Chemistrymolecular electron density theory0104 chemical scienceschemistrynon-covalent interactionsModels ChemicalChemistry (miscellaneous)molecular electron density theory; DFT reactivity indices; electron localisation function; non-covalent interactions; electron density; molecular mechanisms; chemical reactivityMolecular MedicineDensity functional theoryGround stateelectron localisation functionchemical reactivityMolecules; Volume 21; Issue 10; Pages: 1319
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Hydrogen Arrangements on Defective Quasi-Molecular BN Fragments

2019

Considering the ever-increasing interest in metal-free materials, some potential chemical applications of quasi-molecular boron nitride (BN) derivatives were tested. Specifically, the behavior of BN fragments was analyzed when given defects, producing local electron density changes, were introduced by using topological engineering approaches. The inserted structural faults were Schottky-like divacancy (BN-d) defects, assembled in the fragment frame by the subtraction of one pair of B and N atoms or Stone-Wales (SW) defects. This study is aimed at highlighting the role of these important classes of defects in BN materials hypothesizing their future use in H-2-based processes, related to eith…

Exothermic reactionElectron densityMaterials scienceHydrogenGeneral Chemical Engineeringchemistry.chemical_element02 engineering and technology010402 general chemistry01 natural sciencesEndothermic processArticlechemistry.chemical_compoundAdsorptionFragmentation (mass spectrometry)MoleculeQD1-999General Chemistry021001 nanoscience & nanotechnology0104 chemical sciencesChemistrychemistryBoron nitrideChemical physicsSettore CHIM/03 - Chimica Generale E Inorganica0210 nano-technologyh-BN catalysts hydrogen surface arrangements DFT studiesACS Omega
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