Search results for " DOC"

XML document-grammar comparison: related problems and applications

2011

10.2478/s13537-011-0005-1; International audience; XML document comparison is becoming an ever more popular research issue due to the increasingly abundant use of XML. Likewise, a growing interest fosters the development of XML grammar matching and comparison, due to the proliferation of heterogeneous XML data sources, particularly on the Web. Nonetheless, the process of comparing XML documents with XML grammars, i.e., XML document and grammar similarity evaluation, has not yet received the attention it deserves. In this paper, we provide an overview on existing research related to XML document/grammar comparison, presenting the background and discussing the various techniques related to th…

Documentación médica: algunos aspectos críticos actuales

1999

rafael.peris@uv.es Es realitza una breu revisió de la situació de desenvolupament professional i producció científica de la Documentació Mèdica a Espanya, fonamentalment, en l’aplicació hospitalària de la vertent de Documentació assistencial i sanitària i s’analitzen tres aspectes crítics actuals: necessitats d’informació en l’assistència; història clínica; i qualitat. Se realiza una breve revisión de la situación de desarrollo profesional y producción científica de la Documentación Médica en España, fundamentalmente, en la aplicación hospitalaria de la vertiente de Documentación asistencial y sanitaria y se analizan tres aspectos críticos actuales: necesidades de información en la asistenc…

Il reale è ancora tutto da inventare

2021

Il saggio rende omaggio al lavoro della documentarista Cecilia Mangini

Closing and Reporting

2014

It often happens that closing and reporting do not deserve particular attention from the contractor or consultant Project Manager, however, they are important. This chapter analyzes diverse situations that imply risk specifically related to an owner being dissatisfied owing to a deficiency of documentation in quantity and quality handed over, or perhaps due to a lack of quality in finishing concrete work, or through failure to clean the site. The chapter analyzes these aspects, pointing out that closing-out a project is a process as important as the rest of the processes in the project’s life cycle, and examines the need to produce a good Technical Memory that must incorporate a string of i…

Diplomática municipal. Análisis y tipología de la documentación municipal valenciana a principios del siglo XIV

1988

EN EL PRESENTE TRABAJO SE EXPONE EL ESTADO DE LA CUESTION RESPECTO A LA DIPLOMATICA MUNICIPAL, ESPECIALIDAD SURGIDA DEL DESARROLLO DE LA DIPLOMATICA GENERAL COMO CIENCIA HISTORICA Y DE LA EVOLUCION DE LAS MODERNAS TENDENCIAS HISTORIOGRAFICAS. ADEMAS EN ESTE TRABAJO SE ESTABLECE EL ESQUEMA INTERNO DEL DOCUMENTO MUNICIPAL VALENCIANO HASTA LA EPOCA DE ALFONSO IV DE ARAGON, ESBOZANDO LA TIPOLOGIA PROPIA DE LA ESCRIBANIA MUNICIPAL DE VALENCIA EN DICHA EPOCA. (A)

Domestic Violence Interventions in Social and Health Care Settings: Challenges of Temporary Projects and Short-Term Solutions.

2020

Social welfare service and health care providers are in a key position to implement successful domestic violence (DV) interventions. However, it is known that DV intervention and prevention work is often lacking in coordination and continuity. In addition, the limited resources, hectic work pace, and changing practices negatively affect the development of successful ways to prevent and intervene in DV. This qualitative study involving 11 focus groups, composed of social welfare and health care professionals ( n = 51) in a midsized Finnish hospital, examined the challenges and possibilities within DV interventions and the adoption of good practices produced by a DV intervention development …

Nuovi derivati della Dopamina nell’Addiction da sostanze d’abuso: studi preclinici su modelli sperimentali murini

Studies on a new potential dopaminergic agent: in vitro BBB permeability, in vivo behavioural effects and molecular docking evaluation.

2015

2-Amino-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-3-phenyl-propionamide (DA-PHEN) has been previously synthesized to obtain a potential prodrug capable of release dopamine (DA) into CNS. However, DA-PHEN could act per se as a dopaminergic drug. In this study, the permeability transport (Pe), obtained by parallel artificial permeability assay (PAMPA), indicated a low passive transcellular transport (Pe = 0.32 ± 0.01 × 10(-6 )cm/s). Using the Caco-2 cell system, the Papp AP-BL in absorptive direction (3.36 ± 0.02 × 10(-5 )cm/s) was significantly higher than the Papp BL-AP in secretive direction (1.75 ± 0.07 × 10(-5 )cm/s), suggesting a polarized transport. The efflux ratio (Papp AP-BL/Papp BL-AP = 0…

Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and Downregulation of c-Myc.

2021

11 p.-9 fig.-4 tab.

Protocol for rational design of covalently interacting inhibitors.

2014

The inhibition potencies of covalent inhibitors mainly result from the formation of a covalent bond to the enzyme during the inhibition mechanism. This class of inhibitors has essentially been ignored in previous target-directed drug discovery projects because of concerns about possible side effects. However, their advantages, such as higher binding energies and longer drug-target residence times moved them into the focus of recent investigations. While the rational design of non-covalent inhibitors became standard the corresponding design of covalent inhibitors is still in its early stages. Potent covalent inhibitors can be retrieved from large compound libraries by covalent docking approa…