Search results for " DOP"

Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results

2013

International audience; BACKGROUND: To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines. METHODS: Forearm skin blood flow (FSBF), into response to acetylcholine (Ach) (endothelium-dependent vasodilatation), were measured in 24 pregnant control subjects and 28 gestational diabetes mellitus (GDM) women, in the third trimester of gestation. A fasting glycemic and lipidic panel was obtained, and inflammatory cytokines (TNF-alpha and IL-6) and adiponectin were also determined. RESULTS: FSBF is significantly reduced in GDM group compared with control subjects (344.59 +/- 57.791 vs.176.38…

Efectos del tratamiento con agonistas dopaminérgicos sobre las lesiones endometriósicas

2014

La prolactina (PRL) es una hormona hipofisaria que desempeña un papel fundamental en diversas funciones reproductivas, fundamentalmente en la lactancia. En situaciones patológicas que están relacionadas con la presencia de adenomas hipofisarios o ingesta de fármacos psicotropos, los niveles de PRL están elevados y afectan a la función gonadal, pues inhiben la secreción de hormonas hipofisarias como la LH o FSH, ocasionando amenorrea (9%), galactorrea (25%) o ambas (70%) (1).La hiperprolactinemia, por lo tanto, es una causa frecuente de infertilidad por anovulación (2). Por otro lado, la endometriosis es una importante entidad patológica ginecológica estrógeno dependiente cuya prevalencia en…

Evaluación estandarizada del potencial antiangiógénico del agonista dopaminérgico en el tratamiento de la endometriosis

2018

La endometriosis es una enfermedad crónica, de elevada prevalencia y etiopatogenia no claramente establecida, para la que no se dispone, actualmente, de un tratamiento seguro y eficaz a largo plazo. El establecimiento de la angiogénesis como uno de los requisitos fundamentales en la implantación y desarrollo de la enfermedad ha llevado a considerar los fármacos antiangiogénicos como una potencial diana terapéutica. Estos compuestos han demostrado, en modelos animales, reducir el tamaño de las lesiones endometriales; sin embargo, el uso de estos compuestos en humanos se ve limitado por el intolerable perfil de efectos secundarios que presenta. Los agonistas dopaminérgicos (fármacos con un pe…

Cladding-Pumped Er/Yb-Co-Doped Fiber Amplifier for Multi-Channel Operation

2022

The Institute of Solid State Physics, University of Latvia, as a Center of Excellence, has received funding from the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under grant agreement No. 739508, project CAMART2. We express our gratitude to rer. nat. Nicoletta Haarlammert from Fraunhofer Institute for Applied Optics and Precision Engineering IOF for the refractive index measurements of ytterbium/erbium-co-doped fibers. This work is supported by the European Regional Development Fund project No. 1.1.1.1/18/A/068.

Valutazione della funzione diastolica del ventricolo sinistro mediante Doppler tissutale in soggetti ipertesi diabetici e non diabetici

2004

Valutazione della funzione diastolica del ventricolo sinistro mediante Doppler tissutale in soggetti ipertesi con e senza insufficienza renale cronica

2005

Marcadores genéticos dopaminérgicos, serotoninérgicos y de la monoamino-oxidasa (MAO) relacionados con la adicción a los opiáceos, a la cocaína y al …

2013

Introducción: la genética está experimentando un avance espectacular y se postula como una herramienta importante para aportar nuevos descubrimientos en trastornos complejos como son las adicciones. En el presente trabajo se ha realizado un estudio de asociación genética de polimorfismos VNTR, un estudio familiar y un estudio mixto de asociación genético-familiar en una muestra de policonsumidores con adicción al alcohol, la cocaína y los opiáceos. Material y métodos: en una muestra de 302 policonsumidores, se recogieron y genotiparon muestras a partir de células epiteliales de la mejilla para observar las frecuencias de marcadores de las vías dopaminérgica, serotoninérgica y de la MAO en l…

Discussion on 'Estimating depth-averaged velocities in rough channels'

2002

In this short communication the four estimate criteria of the depth-averaged local velocity proposed by Byrd et al. (Earth Surface Processes and Landforms, 2000, Vol. 25, pp. 167-173) are compared both with the three-point method of Bathurst and with the average velocity obtained by integrating the velocity profile (FPa2) suggested by Ferro and Pecoraro (Water Resources Research, 2000, vol. 36, pp. 2761-2770). The comparison was carried out using 84 velocity profiles measured by an acoustic Doppler velocimeter in a rectangular flume with a gravel bed. Copyright © 2002 John Wiley and Sons, Ltd.

DEFECTS IN DOPAMINERGIC PATHWAY AFFECT CONTRACTILITY OF COLON FROM HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (HPRT) KNOCKOUT MICE.

2010

Lesch-Nyhan disease is an X-linked neurobehavioral and metabolic disorder caused by lack of hypoxanthine phosphoribosyltransferase (HPRT), a housekeeping enzyme responsible for recycling purines. The mechanisms underlying the neuropathology are not well understood, but the main neurochemical defect, in central nervous system, is linked to a dysfunction of dopaminergic pathway. In the enteric nervous system the dopaminergic nerves are a subset neurons of regulating gut motility, thus we investigated possible changes in colonic motility of HPRT ¯mice related to the dopaminergic control. We evaluated, in vitro, the mechanical activity of circular muscle strips from wild type and HPRT – mouse c…

Effect of in Doping on the ZnO Powders Morphology and Microstructure Evolution of ZnO:In Ceramics as a Material for Scintillators

2018

Transparent ZnO ceramics are of interest for use as material for high-efficiency fast scintillators. Doping ZnO ceramics in order to improve complex of their properties is a promising direction. In the present research, the role of indium in the ZnO nanopowders surface interactions and in the change of microstructures and photoluminescence (PL) characteristics of sintered cera-mics is considered. Undoped and 0.13 wt% In doped ZnO ceramics are obtained by hot pressing sintering. It has been found that indium leads to the transition of initially faceted ZnO particles to rounded, contributing to good sintering with formation of diffusion active grain boundaries (GBs). Unlike ZnO ceramics, ZnO:…