Search results for " Defects"

showing 10 items of 294 documents

The mechanically-based approach to 3D non-local linear elasticity theory: Long-range central interactions

2010

Abstract This paper presents the generalization to a three-dimensional (3D) case of a mechanically-based approach to non-local elasticity theory, recently proposed by the authors in a one-dimensional (1D) case. The proposed model assumes that the equilibrium of a volume element is attained by contact forces between adjacent elements and by long-range forces exerted by non-adjacent elements. Specifically, the long-range forces are modelled as central body forces depending on the relative displacement between the centroids of the volume elements, measured along the line connecting the centroids. Further, the long-range forces are assumed to be proportional to a proper, material-dependent, dis…

Body forceNon-local elasticityWAVESPROPAGATIONContact forceLattice modelsCentral forcesCentral forceVARIATIONAL-PRINCIPLESMaterials Science(all)Modelling and SimulationVariational formulationsGeneral Materials ScienceVirtual workPLASTICITYSTRAIN-GRADIENT ELASTICITYMathematicsPlane stressDISCRETECONTINUAMechanical EngineeringApplied MathematicsLinear elasticityElastic energySTRAIN-GRADIENT ELASTICITY; VARIATIONAL-PRINCIPLES; CRACK SUBJECT; PROPAGATION; PLASTICITY; DISCRETE; CONTINUA; DEFECTS; LATTICE; WAVESMechanicsDEFECTSCondensed Matter PhysicsLATTICELong-range interactionsClassical mechanicsContact mechanicsStatic–kinematic dualityMechanics of MaterialsModeling and SimulationSettore ICAR/08 - Scienza Delle CostruzioniCRACK SUBJECTInternational Journal of Solids and Structures
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Genome-wide association scan of attention deficit hyperactivity disorder

2008

Contains fulltext : 70191.pdf (Publisher’s version ) (Closed access) Results of behavioral genetic and molecular genetic studies have converged to suggest that genes substantially contribute to the development of attention deficit/hyperactivity disorder (ADHD), a common disorder with an onset in childhood. Yet, despite numerous linkage and candidate gene studies, strongly consistent and replicable association has eluded detection. To search for ADHD susceptibility genes, we genotyped approximately 600,000 SNPs in 958 ADHD affected family trios. After cleaning the data, we analyzed 438,784 SNPs in 2,803 individuals comprising 909 complete trios using ADHD diagnosis as phenotype. We present t…

Candidate geneLinkage disequilibriumGenetics and epigenetic pathways of disease [NCMLS 6]Medizin2804 Cellular and Molecular NeuroscienceGenome-wide association studyNeuroinformatics [DCN 3]Linkage Disequilibrium2738 Psychiatry and Mental Health0302 clinical medicinePerception and Action [DCN 1]Genetics(clinical)ChildGenetics (clinical)Genetics0303 health sciencesHomozygote10058 Department of Child and Adolescent PsychiatrySNP genotypingPsychiatry and Mental healthChild PreschoolData Interpretation Statistical/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFunctional Neurogenomics [DCN 2]Algorithms2716 Genetics (clinical)AdolescentSingle-nucleotide polymorphism610 Medicine & healthBiologyMental health [NCEBP 9]Polymorphism Single NucleotideGenetic determinismArticleGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]SDG 3 - Good Health and Well-beingmedicineSNPAttention deficit hyperactivity disorderHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleles030304 developmental biologyGenome Humanmedicine.diseaseGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCase-Control Studies030217 neurology & neurosurgeryGenome-Wide Association Study
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Evolution of Free Volumes in Polycrystalline BaGa2O4 Ceramics Doped with Eu3+ Ions

2021

H.K. and Y.K. would like to thank A. Ingram for assistance in PAL experiments. The authors thank E.A. Kotomin and M. Brik for the many useful discussions. The research was (partly) performed in the Institute of Solid State Physics, University of Latvia ISSP UL. ISSP UL as the Center of Excellence is supported through the Framework Program for European universities Union Horizon 2020, H2020-WIDESPREAD-01–2016–2017-TeamingPhase2 under Grant Agreement No. 739508, CAMART2 project.

CeramicsGeneral Chemical EngineeringFree-volume defects02 engineering and technologydopingceramics01 natural sciencesInorganic ChemistryFragmentationfragmentation0103 physical sciencesceramics; doping; free-volume defects; positron annihilation; agglomeration; fragmentationDopingGeneral Materials Science010302 applied physicsagglomerationCrystallographyAgglomerationPositron annihilationpositron annihilationfree-volume defects021001 nanoscience & nanotechnologyCondensed Matter PhysicsQD901-999:NATURAL SCIENCES [Research Subject Categories]0210 nano-technologyCrystals
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Organic synthesis of high added value molecules with MOF catalysts

2020

Recent examples of organic synthesis of fine chemicals and pharmaceuticals in confined spaces of MOFs are highlighted and compared with silica-based ordered porous solids, such as zeolites or mesoporous (organo)silica. These heterogeneous catalysts offer the possibility of stabilizing the desired transition states and/or intermediates during organic transformations of functional groups and (C-C/C-N) bond forming steps towards the desired functional high added value molecular scaffolds. A short introduction on zeolites, mesoporous silica and metal-organic frameworks is followed by relevant applications in which confined active sites in the pores promote single or multi-step organic synthesis…

Chemistry OrganicBiochemistryCatalysischemistry.chemical_compoundLEVULINIC ACIDALLYLIC ALCOHOLSMoleculePhysical and Theoretical ChemistryConfined spaceScience & TechnologyChemistryOrganic ChemistryMesoporous silicaMISSING-LINKER DEFECTSTransition stateMESOPOROUS MATERIALSChemistryRECYCLABLE CATALYSTChemical engineeringHETEROGENEOUS CATALYSISC-CMETALPhysical SciencesACTIVE-SITESOrganic synthesisPorous solidsMesoporous materialPROSTAGLANDIN UNSATURATED-KETONESOrganic & Biomolecular Chemistry
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Textures in hexatic films of nonchiral liquid crystals: Symmetry breaking and modulated phases

1994

Novel modulated textures, such as stripes and multiarmed star defects, have been observed in freely suspended films of nonchiral liquid crystals just below the smectic-$C$ to hexatic phase transition. Detailed studies using depolarized reflection microscopy suggest that the stripes are locally chiral surface splay domains of the smectic-$L$ phase, a tilted hexatic not previously identified in thermotropic liquid crystals. Line defects which form additional domain walls in the hexatic lattice lead to characteristic modulations of the basic one-dimensional stripe pattern. Inside thick circular islands, for example, stripes form circumferentially and the lines form centered 12-armed stars, res…

Condensed Matter::Soft Condensed MatterLine defectsMaterials scienceCondensed matter physicsLiquid crystalCondensed Matter::SuperconductivityLattice (order)MicroscopySymmetry breakingChiral symmetry breakingHexatic phaseThermotropic crystalPhysical Review E
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Congenital heart defects in newborns with apparently isolated single gastrointestinal malformation: A retrospective study.

2015

Abstract Background Congenital gastrointestinal system malformations/abdominal wall defects (GISM) may appear as isolated defects (single or complex), or in association with multiple malformations. The high incidence of association of GISM and congenital heart defects (CHD) in patients with syndromes and malformative sequences is known, but less expected is the association of apparently isolated single GISM and CHD. The aim of this study was to investigate the frequency of CHD in newborns with isolated GISM, and the possibility to modify the diagnostic-therapeutic approach just before the onset of cardiac symptoms or complications. Methods Anamnestic, clinical, and imaging data of newborns …

Congenital abnormalitieHeart Defects CongenitalMalePediatricsmedicine.medical_specialtyHeart diseaseGastrointestinal Diseasesmedicine.medical_treatment030204 cardiovascular system & hematologyVentricular septal defectAbdominal wallSepsis03 medical and health sciences0302 clinical medicine030225 pediatricsInternal medicineIntensive Care Units NeonatalmedicineEndocarditisHumansRetrospective Studiesbusiness.industryIntestinal atresiaCardiovascular abnormalitieInfant NewbornObstetrics and GynecologyRetrospective cohort studymedicine.diseaseIntestinal atresiaGastrointestinal Tractmedicine.anatomical_structureMesenterium defectDigestive system abnormalitiePediatrics Perinatology and Child HealthCardiologyFemalebusinessCentral venous catheterAbdominal surgeryEarly human development
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Relative incidence and mortality of congenital heart defects diagnosed by angiohemodynamic methods: a 17-year study.

1992

Over a 17-year period (January 1971 to January 1988), 2322 children, aged 0-14 years, were diagnosed as having congenital heart disease (CHD) by cardiac catheterization and angiography. Excluding those with highly complex or undiagnosed defects, there were 2156 children with CHD, 72.4% of whom were treated surgically, with a total surgical mortality rate of 24.1%. After a mean follow-up of 9 years the overall mortality of the cohort was 29.9%, 29.1% occurring in the first month of life, 39.6% between 1 month and 1 year, and 31.2% between 1 and 14 years. The incidence, mortality, and age at death of each cardiac defect are presented and compared with the results of other studies. The overall…

Cross-Cultural ComparisonHeart Defects CongenitalMalePediatricsmedicine.medical_specialtyCardiac CatheterizationHeart diseaseAdolescentRelative incidencemedicine.medical_treatmentCohort StudiesPostoperative ComplicationsmedicineHumansChildCardiac catheterizationmedicine.diagnostic_testbusiness.industryIncidence (epidemiology)AngiocardiographyPalliative CareHemodynamicsInfant NewbornInfantVascular surgerymedicine.diseaseCardiac surgerySurvival RateSpainChild PreschoolPediatrics Perinatology and Child HealthCohortAngiographyFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesPediatric cardiology
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Light Sensitive Lattice Defects In BaTiO 3 Containing Fe

1989

Electron spin resonance spectra, which can consistently be explained by the models Fe4+ - Vo and Fe5+ - vBa, have been observed with BaTiO3 containing Fe. Also Fe3+ and - Fe3+ - Vo have been identified. All these centers as well as several unidentified ones are observed to change their charge states under illumination. They thus are possibly in involved in photorefractive processes in BaTiO3 containing Fe.

CrystallographyMaterials sciencechemistryCondensed matter physicsLattice defectschemistry.chemical_elementLight sensitivePhotorefractive effectElectronFerroelectricityOxygenMicrowaveIonSPIE Proceedings
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Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

2012

Coats plus is a highly pleiotropic disorder particularly affecting the eye, brain, bone and gastrointestinal tract. Here, we show that Coats plus results from mutations in CTC1, encoding conserved telomere maintenance component 1, a member of the mammalian homolog of the yeast heterotrimeric CST telomeric capping complex. Consistent with the observation of shortened telomeres in an Arabidopsis CTC1 mutant and the phenotypic overlap of Coats plus with the telomeric maintenance disorders comprising dyskeratosis congenita, we observed shortened telomeres in three individuals with Coats plus and an increase in spontaneous γ 3H2AX-positive cells in cell lines derived from two affected individual…

DNA polymeraseMolecular Sequence DataTelomere-Binding ProteinsHistones/metabolismHDE GENHDE NEU PEDCST complexCEREBRORETINAL MICROANGIOPATHY FAMILIAL SYNDROME CALCIFICATIONS CYSTS PROTEIN DNA LEUKOENCEPHALOPATHY EVOLUTION DEFECTSHistoneschemistry.chemical_compoundAbnormalities Multiple/geneticsGeneticsmedicineAbnormalities MultipleGenetic Predisposition to DiseaseGeneticsTelomere-binding proteinTelomere/pathologyddc:618biologyBase SequenceGenetic Predisposition to Disease/geneticsDNA replicationSequence Analysis DNATelomeremedicine.diseaseFlow CytometryTelomereCell biologyRetinal Telangiectasis/genetics/pathologychemistrySequence Analysis DNA/methodsbiology.proteinRetinal TelangiectasisPrimaseTelomere-Binding Proteins/geneticsDNADyskeratosis congenitaNature Genetics
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Long-Range and Short-Range Structure of Proton-Conducting Y:BaZrO3

2011

Yttrium-doped barium zirconate (BZY) is the most promising candidate for proton-conducting ceramics and has been extensively studied in recent years. The detailed features of the crystal structure, both short-range and long-range, as well as the crystal chemistry driving the doping process, are largely unknown. We use very high resolution X-ray diffraction (HR-XRD) to resolve the crystal structure, which is very slightly tetragonally distorted in BZY, while the local environment around Zr4+ and Y3+ is probed with extended X-ray absorption fine structure (EXAFS), and the symmetry and vibrations are investigated by using Raman spectroscopy. It is found that barium zirconate shows some degree …

DYNAMICSRAMAN-SCATTERINGMaterials scienceCrystal chemistryGeneral Chemical EngineeringYTTRIUMRAMAN-SCATTERING; LOCAL ENVIRONMENT; BARIUM CERATE; SPECTROSCOPY; YTTRIUM; BAZR0.9Y0.1O2.95; STRONTIUM; DYNAMICS; DEFECTS; OXIDESCrystal structuresymbols.namesakeSTRONTIUMMaterials ChemistryLOCAL ENVIRONMENTBAZR0.9Y0.1O2.95OXIDESSpectroscopyProton conductorSPECTROSCOPYExtended X-ray absorption fine structureDopingDEFECTSGeneral ChemistryCrystallographysymbolsRaman spectroscopyBARIUM CERATERaman scatteringChemistry of Materials
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