Search results for " Delay"
showing 10 items of 442 documents
Early markers of language delay in children with and without family risk for dyslexia
2015
Accepted manuscript version. Published version at http://doi.org/10.1177/0142723715596122. This study examined the extent to which receptive and productive vocabulary between ages 12 and 18 months predicted language skills at age 24 months in children born with family risk for dyslexia (FR) and a control group born without that risk. The aim was to identify possible markers of early language delay. The authors monitored vocabulary growth in 32 FR children and 21 control children longitudinally by using the Norwegian adaption of the MacArthur–Bates Communicative Development Inventories. The results show different patterns in the two groups: the study found a stronger interdependence of early…
Is TCP Packet Reordering Always Harmful?
2004
IP networks do not provide any guarantee that packets belonging to the same flow are delivered in the correct order. Out-of-order reception of packets was commonly considered due to pathological network conditions (such as link failures, etc.). However, it has been shown that packet reordering is a phenomenon which occurs even in normal network operation, due to a number of link-level and/or router-level implementation features, such as local parallelism and load balancing. Packet reordering is intuitively considered as a negative phenomenon, which may severely affect TCP traffic performance since it is expected to cause inefficient usage of the available link bandwidth and is expected to i…
New insight into the inhibition of the inflammatory response to experimental delayed-type hypersensitivity reactions in mice by scropolioside A.
2006
Scropolioside A, an iridoid isolated from Scrophularia auriculata ssp. pseudoauriculata, showed anti-inflammatory properties against different experimental models of delayed-type hypersensitivity. This iridoid reduced the oedema induced by oxazolone by 79% (72 h) at 0.5 mg/ear while reducing that induced by sheep red blood cells by 47% (18 h), 45% (24 h) and 36% (48 h) at 10 mg/kg. In vivo it reduced both oedema formation and cell infiltration whereas in vitro it reduced the proliferation of activated T-lymphocytes (IC50 of 67.74 microM). Treatment with scropolioside A (100 microM) 18 and 24 h after phytohemagglutinin stimulation increased the number of cells arrested in the subG(0) phase w…
Real-world effectiveness of long acting aripiprazole: Treatment persistence and its correlates in the Italian clinical practice
2019
Abstract Objectives To identify the variables that are associated with persistence to Aripiprazole-Long Acting (A-LAI), in adult patients with schizophrenia. Methods Observational, retrospective, non-interventional study involving 261 patients with schizophrenia. Results Eighty-six percent of study subjects were persistent for at least 6 months. All subjects with baseline CGI-S of 1 or 2, 95% of subjects with CGI-S of 3, 86% with CGI-S of 4, 82% of subjects with CGI-S of 5, 73% of subjects with CGI of 6 and 90% of subjects with CGI of 7 were persistent. A-LAI treatment continuation rate was higher in patients with: 1) baseline CGI score ≤ 4; 2) schizophrenia dimension (LDPS) mania score ≤ 5…
Off-label long acting injectable antipsychotics in real-world clinical practice: a cross-sectional analysis of prescriptive patterns from the STAR Ne…
2022
Introduction: Information on the off–label use of Long–Acting Injectable (LAI) antipsychotics in the real world is lacking. In this study, we aimed to identify the sociodemographic and clinical features of patients treated with on– vs off–label LAIs and predictors of off–label First– or Second–Generation Antipsychotic (FGA vs. SGA) LAI choice in everyday clinical practice. Method: In a naturalistic national cohort of 449 patients who initiated LAI treatment in the STAR Network Depot Study, two groups were identified based on off– or on–label prescriptions. A multivariate logistic regression analysis was used to test several clinically relevant variables and identify those associated with th…
Finite-Time Hâ Filtering for T-S Fuzzy Discrete-Time Systems with Time-Varying Delay and Norm-Bounded Uncertainties
2015
In this paper, we investigate the filtering problem of discrete-time Takagi–Sugeno (T–S) fuzzy uncertain systems subject to time-varying delays. A reduced-order filter is designed. With the augmentation technique, a filtering error system with delayed states is obtained. In order to deal with time delays in system states, the filtering error system is first transformed into two interconnected subsystems. By using a two-term approximation for the time-varying delay, sufficient delay-dependent conditions of finite-time boundedness and $H_{\infty }$ performance of the filtering error system are derived with the Lyapunov function. Based on these conditions, the filter design methods are propose…
Output-feedback-based H∞ control for vehicle suspension systems with control delay
2014
This paper deals with the problem of output-feedback H∞ control for a class of active quarter-car suspension systems with control delay. The dynamic system of the suspension systems is first formed in terms of the control objectives, i.e., ride comfort, road holding, suspension deflection, and maximum actuator control force. Then, the objective is to the design of the dynamic output-feedback H∞ controller in order to ensure asymptotic stability of the closed-loop system with H∞ disturbance attenuation level and the output constraints. Furthermore, using Lyapunov theory and linear matrix inequality (LMI) approach, the existence of admissible controllers is formulated in terms of LMIs. With t…
Local Capacity $H_{\infty}$ Control for Production Networks of Autonomous Work Systems With Time-Varying Delays
2010
This paper considers the problem of local capacity H∞ control for a class of production networks of autonomous work systems with time-varying delays in the capacity changes. The system under consideration is modeled in a discrete-time singular form. Attention is focused on the design of a controller gain for the local capacity adjustments which maintains the work-in-progress (WIP) in each work system in the vicinity of planned levels and guarantees the asymptotic stability of the system and reduces the effect of the disturbance input on the controlled output to a prescribed level. In terms of a matrix inequality, a sufficient condition for the solvability of this problem is presented using …
A Lyapunov–Razumikhin approach for stability analysis of logistics networks with time-delays
2012
Logistics network represents a complex system where different elements that are logistic locations interact with each other. This interaction contains delays caused by time needed for delivery of the material. Complexity of the system, time-delays and perturbations in a customer demand may cause unstable behaviour of the network. This leads to the loss of the customers and high inventory costs. Thus the investigation of the network on stability is desired during its design. In this article we consider local input-to-state stability of such logistics networks. Their behaviour is described by a functional differential equation with a constant time-delay. We are looking for verifiable conditio…
Early-infantile onset epilepsy and developmental delay caused by bi-allelic GAD1 variants
2020
Mice lacking GAD1 show neonatal mortality, but the human phenotype associated with GAD1 disruption is poorly characterized. Neuray et al. describe six patients with biallelic GAD1 mutations, presenting with early-infantile onset epilepsy, neurodevelopmental delay, muscle weakness and non-CNS manifestations.