Search results for " Delay"
showing 10 items of 442 documents
Evening salivary cortisol and alpha-amylase at 14months and neurodevelopment at 4years: Sex differences.
2017
Stress system activity in early life can have long-term effects on neurodevelopment. The main aim of this study was to assess the association of child evening salivary cortisol and alpha-amylase basal levels at 14months of age with longer-term neuropsychological development at 4years in a low-risk population-based birth cohort derived from the INMA (Environment and Childhood) project in Spain. We included 186 parent-children pairs with information on both stress system activity and neurodevelopment. Both stress markers at 14months of age showed an association with neuropsychological development at 4years. Salivary cortisol showed a sex-specific pattern of association. In girls, cortisol lev…
Single, intense prenatal stress decreases emotionality and enhances learning performance in the adolescent rat offspring: Interaction with a brief, d…
2006
Perinatal manipulations can lead to neurobehavioural changes in the progeny. In this study we investigated, in adolescent male rat offspring, the consequences of a single, intense prenatal stress induced by a 120 min-maternal immobilization at gestational day 16, and of a daily, brief maternal separation from postnatal day 2 until 21, on: unconditioned fear/anxiety-like behaviour in open field and in elevated plus-maze; learning performance in the "Can test", a non-aversive spatial and tactile/visual task; corticosterone plasma levels under basal and stress-induced conditions. Our results indicate that both prenatal stress and maternal separation procedures decrease emotionality and enhance…
Keeping memory for intentions: A cTBS investigation of the frontopolar cortex
2011
The present study aimed to investigate the role of frontopolar cortex in prospective memory (PM) by means of inhibitory theta-burst stimulation (cTBS). "Experiment 1"-8 volunteers were evaluated after inhibitory cTBS over left Brodmann area (BA) 10, right BA10, and Cz. In the PM procedure, sequences of 4 words each were presented. During the intersequence delay, subjects had to repeat the sequence in the observed order (ongoing task forward) or in the reverse order (backward). At the occurrence of a target word, subjects had to press a key on the keyboard (PM task). Recall and recognition of the target words were also tested. PM accuracy was lower after cTBS over left BA10 compared with Cz …
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
2019
Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…
Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs
2019
There is a growing body of evidence linking maternal overnutri-tion to obesity and psychopathology that can be conserved acrossmultiple generations. Recently, we demonstrated in a maternalhigh-fat diet (HFD; MHFD) mouse model that MHFD inducedenhanced hedonic behaviors and obesogenic phenotypes thatwere conserved across three generations via the paternal lineage,which was independent of sperm methylome changes. Here, weshow that sperm tRNA-derived small RNAs (tsRNAs) partly contrib-ute to the transmission of such phenotypes. We observe increasedexpression of sperm tsRNAs in the F1 male offspring born to HFD-exposed dams. Microinjection of sperm tsRNAs from the F1-HFDmale into normal zygotes…
Rubinstein–Taybi syndrome 2 with cerebellar abnormality and neural tube defect
2019
Rubinstein-Taybi syndrome (RSTS) is a rare dominant disorder with intellectual disability, postnatal growth deficiency, and multiple congenital anomalies. Approximately 50-70% of the patients have a mutation in the CREBBP gene (RSTS1) and 5-10% display an EP300 gene mutation (RSTS2). Craniospinal abnormalities such as microcranium, scoliosis, and lordosis are frequent findings in RSTS1, but malformations of the brain or spinal cord are seen only occasionally. Here, we report on a 3-year-old boy with facial abnormalities of RSTS, broad thumbs and halluces, developmental delay, autistic features, cerebellar underdevelopment, and a neural tube defect. Molecular diagnostic of the CREBBP and EP3…
Development and analysis of a model based on chirped fiber Bragg gratings employed for cracks characterization in materials
2018
In this work a model was developed that allows to understand the behavior of a chirped fiber Bragg grating for the detection and characterization of cracks in materials. In addition to the amplitude response, we show that the group delay of the grating provides useful information for the characterization of the crack. The position of the crack can be determined thanks to the linear chirp of the grating that fixes a correlation between the spatial position and both, the wavelength and the group delay. However, our analysis shows that this simple approach has a source of error, which can be overcome if a controllable external strain can be applied to the embedded grating, additional to the st…
Continuous Broadband MWP True-Time Delay with PbS-PMMA and -SU8 waveguides
2016
[EN] A new microwave true-time delay (TTD) photonic unit based on the dispersion of PbS colloidal quantum dots (QDs) in a Polymethyl methacrylate (PMMA) and the SU8 photoresist is presented. With this aim, the PbS-PMMA and PbS-SU8 nanocomposites are integrated on a silicon platform in the form of a planar and ridge waveguides, respectively. When PbS QDs on those structures are pumped below their band-gap, a phase shift and a temporal delay in an optically conveyed (at 1550 nm) microwave signal is performed. The results of these devices show potential benefits over current TTD technologies, since the proposed photonic waveguide structures allows real-time adjustment of the temporal delay by …
MWP true time delay implemented in PbS-SU8 waveguides
2015
Es presenta un nou tipus de dispositiu de retard en temps real de microones (TTD) basat en la dispersió de punts quàntics col·loïdals PbS (QD) en el fotoresist SU8 disponible comercialment. Amb aquest propòsit, els nanocompostos PbS-SU8 s’integren en una plataforma de silici en forma de guies d’ones de cresta. Quan aquestes estructures es bomben a longituds d’ona per sota de l’interval de banda dels PbS QD, es realitza un desplaçament de fase en un senyal de microones transmès òpticament (a 1550 nm) i, per tant, es produeix un retard temporal. A més, es milloren els resultats mitjançant la implementació d’una nova guia d’ones de doble capa de cresta composta per un nanocompost PbS-SU8 i una…
On the stability analysis for impulsive switching system with time-varying delay
2014
This paper focuses on the stability and stabilization problem for a neutral impulsive switching system with time-varying delay. Based on LMI method and optimization technologies, some stability criteria are derived for this kind of system. Some example and numerical simulation are given to demonstrate the effectiveness of our theoretical results. Refereed/Peer-reviewed