Search results for " Digital"
showing 10 items of 1026 documents
Computational volumetric reconstruction of integral imaging with improved depth resolution considering continuously non-uniform shifting pixels
2018
Abstract In this paper, we propose a new computational volumetric reconstruction technique of three-dimensional (3D) integral imaging for depth resolution enhancement by using non-uniform and integer-valued shifting pixels. In a typical integral imaging system, 3D images can be recorded and visualized using a lenslet array. In previous studies, many computational reconstruction techniques such as computational volumetric reconstruction and pixel of elemental images rearrangement technique (PERT) have been reported. However, a computational volumetric reconstruction technique has low visual quality and depth resolution because low-resolution elemental images and uniformly distributed shiftin…
Open data and digital morphology
2017
International audience; Over the past two decades, the development of methods for visualizing and analysing specimens digitally, in three and even four dimensions, has transformed the study of living and fossil organisms. However, the initial promise that the widespread application of such methods would facilitate access to the underlying digital data has not been fully achieved. The underlying datasets for many published studies are not readily or freely available, introducing a barrier to verification and reproducibility, and the reuse of data. There is no current agreement or policy on the amount and type of data that should be made available alongside studies that use, and in some cases…
OMiLAB: A Smart Innovation Environment for Digital Engineers
2020
This position paper introduces a Smart Innovation Environment for experimentation related to digital transformation projects, for the consolidation of a proposed "Digital Engineer" skill profile (with a business-oriented facet labelled as "Digital Innovator"). In the Internet of Things era, this profile implies the ability to perform both digital design and engineering activities, to semantically bridge multiple layers of abstraction and specificity - from business analysis down to cyber-physical engineering. In the paper's proposal, this integration is enabled by conceptual modelling methods and interoperable modelling tools, tailored to support the creation of Digital Twins for innovative…
Simulación de Plataformas Robóticas de Movimiento para Aplicaciones de Realidad Virtual Mediante Filtros Digitales
2017
[ES] El uso de plataformas robóticas de movimiento en simuladores de vehículos y aplicaciones de Realidad Virtual es relativamente habitual. Sin embargo, el ajuste de los algoritmos que controlan su funcionamiento, denominados algoritmos de washout, no es sencillo y requiere de numerosas pruebas hasta obtener una apropiada fidelidad de movimiento. Disponer de herramientas que permitan simular plataformas de movimiento puede permitir simplificar esta tarea. Es por ello que este trabajo presenta un método para la caracterización y simulación de manipuladores robóticos mediante filtros digitales de segundo orden, sencillo de implementar y ajustar a partir de una caracterización previa. El simu…
ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice: Review
2020
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Update on oral-facial-digital syndromes (OFDS)
2016
Oral-facial-digital syndromes (OFDS) represent a heterogeneous group of rare developmental disorders affecting the mouth, the face and the digits. Additional signs may involve brain, kidneys and other organs thus better defining the different clinical subtypes. With the exception of OFD types I and VIII, which are X-linked, the majority of OFDS is transmitted as an autosomal recessive syndrome. A number of genes have already found to be mutated in OFDS and most of the encoded proteins are predicted or proven to be involved in primary cilia/basal body function. Preliminary data indicate a physical interaction among some of those proteins and future studies will clarify whether all OFDS prote…
Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue
2018
Abstract Background Gene expression profiling (GEP) studies recognized a prognostic role for tumor microenvironment (TME) in diffuse large B-cell lymphoma (DLBCL), but the routinely adoption of prognostic stromal signatures remains limited. Patients and methods Here, we applied the computational method CIBERSORT to generate a 1028-gene matrix incorporating signatures of 17 immune and stromal cytotypes. Then, we carried out a deconvolution on publicly available GEP data of 482 untreated DLBCLs to reveal associations between clinical outcomes and proportions of putative tumor-infiltrating cell types. Forty-five genes related to peculiar prognostic cytotypes were selected and their expression …
Intra-tumour heterogeneity of diffuse large B-cell lymphoma involves the induction of diversified stroma-tumour interfaces
2020
Abstract Background Intra-tumour heterogeneity in lymphoid malignancies encompasses selection of genetic events and epigenetic regulation of transcriptional programs. Clonal-related neoplastic cell populations are unsteadily subjected to immune editing and metabolic adaptations within different tissue microenvironments. How tissue-specific mesenchymal cells impact on the diversification of aggressive lymphoma clones is still unknown. Methods Combining in situ quantitative immunophenotypical analyses and RNA sequencing we investigated the intra-tumour heterogeneity and the specific mesenchymal modifications that are associated with A20 diffuse large B-cell lymphoma (DLBCL) cells seeding of d…
Medios digitales, transmisión de información y formación del espacio público: comunicación de masas y comunicación en red ante el 11M
2004
En los días transcurridos entre el atentado del 11M y las elecciones del 14M se vivió en España un intenso debate en torno a la autoría de los atentados que tuvo una incidencia difícil de determinar en las elecciones. Un debate cuyo punto de partida, a su vez, constó de dos condicionantes principales: primero, las diferentes estrategias informativas de Gobierno y oposición, así como los diversos medios de comunicación, en cuanto a la autoría del atentado, y segundo, la sobreinformación del público, a través tanto de los medios de comunicación de masas tradicionales como de medios de información alternativos (televisiones por cable, canales temáticos, la Internet) e interpersonales (principa…