Search results for " Disruption"

Digital solutions transform the forest-based bioeconomy into a digital platform industry : a suggestion for a disruptive business model in the digita…

2018

With the notion that the transformation of the forest-based bioeconomy in recent years provides insightful suggestions not only on the bioeconomy, but on business innovation, this paper conducts an empirical analysis of the transformation and attempts to extract suggestions for a digital-solution-driven, disruptive business model in the digital economy. Notwithstanding the potential broad cross-sectoral benefits, the natural environment, locality constraints, and incessant challenge of distance have impeded the balanced development of the bioeconomy. However, driven by digital solutions, the bioeconomy has taken big steps forward in recent years. Digitalization has enabled real-time, end-to…

Digital Solutions in the Forest-Based Bioeconomy

2019

This chapter aims to illustrate the potential and significance of forest-based industry to take the lead in the sustainable development of the bio-based economy under digitalization. The digital solutions are transforming the forest-based industry by enabling the real-time end-to-end supply chain visibility, stock level optimization, demand planning, and real-time order status tracking and transparent, speedy, and hassle-free order fulfillment. In addition, increasing diversification corresponds to eco-consciousness, and shift in people’s preferences induces the transformation of forest-based bioeconomy into a digital platform industry. Further, this chapter will highlight the circular econ…

Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis.

2013

Objective: To explore whether the Dll4/Notch1 pathway plays a key role in regulating the vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) driven decidual angiogenesis and related pregnancy through induction of a tip/stalk phenotype. Methods: Progesterone-replaced ovariectomized pregnant mice received a single injection of YW152F (Dll4 blocking antibody, BAb) or placebo at embryonic day (E) 4.5. Animals were sacrificed at different time points; blood and uterus were collected for further analysis. Number of embryos and implantation site, uteri weight, and serum progesterone levels were assessed. Alterations in the tip/stalk phenotype were determined by quantitative immunofl…

Obstructive Sleep Apnea and the Brain

2018

Transformation of the Forest-based Bioeconomy by Embracing Digital Solutions

2017

This paper attempts to explore a new insight to both industrialized and growing economies by demonstrating a digital-driven creative disruption in the forest-based bioeconomy which is beginning to replace its conventional and narrow concept of a forest-blinded economy. Notwithstanding the potential broad cross-sectoral benefits to both industrialized and growing economies, natural environments and locality constraints and the incessant challenge of distance have impeded balanced development of this economy. However, driven by digital solutions the economy has taken big steps forward in recent years. Digitalization has enabled real-time end-to-end supply chain visibility, improved delivery a…

Lesioni cutanee stellate e simmetriche in un gemello “rimasto solo”

2021

The incidence of multiple pregnancy has increased, particularly because of the advances in assisted reproductive technologies. Multiple gestations are high risk pregnancies, especially the monochorionic ones. Two/thirds of initially twin pregnancies result in singles at birth, a condition defined as vanishing twin syndrome. The intrauterine death of one of the twins can cause direct fetal damage to the surviving one on several levels. The paper describes the case of a child born from twin pregnancy that was interrupted for one of the co-twins at early second trimester of gestation who presented with aplasia cutis congenita.