Search results for " Dysplasia"
showing 10 items of 206 documents
Distribution of human papillomavirus types in women from Valencia, Spain, with abnormal cytology.
2010
Objective To determine human papillomavirus (HPV) types among cervical smears using polymerase chain reaction (PCR) and to contribute to the knowledge of human papillomavirus genotype distribution and prevalence of oncogenic types in cervical lesions in Spain. Study Design Consensus PCR and direct sequencing of PCR products (DNA HPV typing) were used in a retrospective study to determinate the type or types of HPV on 974 cytology smears of women with abnormal cytology results. Results Of 974 smears, 79.8% were high-risk (H-R) HPVs, 19.7% low-risk (L-R) HPVs, 4.6% indeterminate-risk (I-R) HPVs, considering both single and multiple infections. Multiple infections were detected in 4.7% of the …
Potential impact of a nonavalent HPV vaccine on HPV related low-and high-grade cervical intraepithelial lesions: A referral hospital-based study in S…
2017
ABSTRACT While bivalent and quadrivalent HPV vaccines have been used for about 10 years, a nonavalent vaccine against HPV types 6/11/16/18/31/33/45/52 and 58 has been recently approved by FDA and EMA and is now commercially available. The objective of our study was to evaluate the potential impact of the nonavalent vaccine on HPV infection and related low- and high-grade squamous intraepithelial lesions (LSIL, HSIL), compared to the impact of the quadrivalent vaccine, in a female population living in Sicily (Italy). Low estimates of HPV vaccine impact were calculated as prevalence of HPV 6/11/16/18/31/33/45/52 and 58 genotypes, alone or in association, but excluding presence of other HPV ty…
Human papillomaviruses in oral carcinoma and oral potentially malignant disorders: a systematic review
2011
Oral Diseases (2011) 17 (Suppl. 1), 58–72 Objectives: Human papillomavirus (HPV) in oral carcinoma (OSCC) and potentially malignant disorders (OPMD) is controversial. The primary aim was to calculate pooled risk estimates for the association of HPV with OSCC and OPMD when compared with healthy oral mucosa as controls. We also examined the effects of sampling techniques on HPV detection rates. Methods: Systematic review was performed using PubMed (January 1966–September 2010) and EMBASE (January 1990–September 2010). Eligible studies included randomized controlled, cohort and cross-sectional studies. Pooled data were analysed by calculating odds ratios, using a random effects model. Risk o…
Prognostic value of the immunohistochemical detection of epithelial-mesenchymal transition biomarkers in oral epithelial dysplasia : a systematic rev…
2019
Background Oral potentially malignant disorders (OPMDs) comprise a range of clinical-pathological alterations that are frequently characterized as architectural and cytological derangements upon histological analysis. Epithelial-mesenchymal transition (EMT) has been proposed as a critical mechanism for the acquisition of the malignant phenotype in neoplastic epithelial processes. This study aims to systematically review the current findings on the immunohistochemical expression of epithelial-mesenchymal transition markers in oral potentially malignant disorders and to evaluate their possible application as biomarkers associated with the progression of oral epithelial dysplasias. Material an…
INTERNATIONAL JOURNAL OF CLINICAL DENTISTRY
2018
Diagnosis and Management of Oral Langerhans Cell Histiocytosis Emanoele Paixão da Silva Silva, Carina Myung Rodenbeck, Monira Samáan Kallas, Cássia Maria Fischer Rubira, and Paulo Sérgio da Silva Santos Mandibular-Infected Buccal Cyst: Unique Radiographic Appearance Gustavo Zanna Ferreira, Cássia Maria Fischer Rubira, Letícia Rodrigues Nery, Alberto Consolaro, Izabel Regina Fischer Rubira-Bullen, and Paulo Sérgio da Silva Santos PRF - The Magical Resort in Surgical Dentistry Archana Mootha, Julie Toby Thomas, Sankari Malaiappan, Sheeja S. Varghese, and N. D. Jayakumar Endodontic Management of a Macrodont: A Rare Tooth Anomaly Rahul Rathi and Priti Saroha Maxillary Canine Root Resorption Con…
The role of the dentist in the diagnosis and management of patients with oral mucosal diseases
2021
Based on a few case reports of oral mucosal diseases a number of questions is raised about the role of dentists-general practitioners in the diagnostic procedure and management of patients with such diseases. For instance, are dentists prepared to prescribe topical corticosteroids and should dentists be taught how and when to take a biopsy? And how about palpation of the neck? A strong recommendation is made to take clinical pictures for proper documentation and, if needed, for telediagnostic procedures. Another issue relates to the communication between dentists and dental specialists when dealing with patients with oral diseases. In case of a patient suffering from burning mouth syndrome …
Orthodontic treatment of patient with maxillofacial fibrous dysplasia : a case report
2019
Fibrous dysplasia is a benign skeletal disorder in which the normal bone and marrow are replaced by fibrous tissue and haphazardly distributed woven bone. The aim of this case report is to discuss the orthodontic treatment of a 13-year-old patient with fibrous dysplasia in the left maxilla. The patient had rotated maxillary second premolars, moderate crowding in both maxillary and mandibular arches with low maxillary frenal attachment. Orthodontic treatment was done with full fixed appliance and extraction of maxillary and mandibular third molars. Maxillary frenectomy and free gingival graft in mandibular anterior region were performed by a periodontist. The oral and maxillofacial surgery t…
Imaging in Prune Belly Syndrome and Other Syndromes Affecting the Urogenital Tract
2018
The absence of the abdominal musculature, urinary tract dilatation, and bilateral undescended testis is known as prune belly syndrome (PBS) (Eagle and Barrett 1950; Greskovich and Nyberg 1988; Williams 1982). The classical syndrome is also known as triad syndrome, Eagle-Barrett syndrome, or abdominal muscular deficiency syndrome. There is a broad spectrum of malformations with severe dilatation of the urinary tract as a consequence of aplasia of the musculature. The pathogenetic mechanism is different from that of dilatation as a consequence of supra- or infravesical obstruction. Some patients with prune belly syndrome have a real obstruction, such as urethral aplasia with oligohydramnios s…
An unusual case of rudimentary parotid gland with distended Stensen duct
2010
Congenital absence or rudiment major salivary glands, especially of the parotid glands, are a rare entity. Aplasia of parotid glands has been described alone or in association with abnormalities of other salivary glands, first branchial arch developmental disturbances and other congenital anomalies such as lacrimoauriculodentodigital syndrome, mandibulofacial dysostosis and ectodermal dysplasia. Absence is most commonly unilateral, and may be associated with accessory or rudimentary glandular tissue. There are several reported cases of isolated patulous Stensen’s duct causing air insufflations in the glands and recurrent parotid gland enlargement. However, in the literature there is no repo…
Analysis of the RET, GDNF, EDN3, and EDNRB genes in patients with intestinal neuronal dysplasia and Hirschsprung disease
2001
BACKGROUNDHirschsprung disease (HSCR) is a frequent congenital disorder with an incidence of 1 in 5000 live births, characterised by the absence of parasympathetic intramural ganglion cells in the hindgut resulting in intestinal obstruction in neonates and severe constipation in infants and adults. Intestinal neuronal dysplasia (IND) shares clinical features with HSCR but the submucosal parasympathetic plexus is affected. IND has been proposed as one of the most frequent causes of chronic constipation and is often associated with HSCR.METHODSWe examined 29 patients diagnosed with sporadic HSCR, 20 patients with IND, and 12 patients with mixed HSCR/IND for mutations in the coding regions of …