Search results for " East"

showing 10 items of 305 documents

Genetic discontinuity between local hunter-gatherers and central Europe's first farmers.

2009

Cultivating Farmers Were the ancestors of modern Europeans the local hunter-gatherers who assimilated farming practices from neighboring cultures, or were they farmers who migrated from the Near East in the early Neolithic? By analyzing ancient hunter-gatherer skeletal DNA from 2300 to 13,400 B.C.E. Bramanti et al. (p. 137 , published online 3 September) investigated the genetic relationship of European Ice Age hunter-gatherers, the first farmers of Europe, and modern Europeans. The results reject the hypothesis of direct continuity between hunter-gatherers and early farmers and between hunter-gatherers and modern Europeans. Major parts of central and northern Europe were colonized by incom…

MaleArchaeogeneticsHistorymedia_common.quotation_subjectImmigrationPopulationEuropean Continental Ancestry GroupPopulation DynamicsAgriculture; DNA Mitochondrial; Emigration and Immigration; Europe; European Continental Ancestry Group; Female; Genetic Variation; Haplotypes; History Ancient; Humans; Male; Population Dynamics; ProbabilityBiologyDNA MitochondrialWhite PeopleNOAncientDemic diffusionHumansDomesticationeducationHunter-gathererHistory Ancientmedia_commonProbabilityGeneticseducation.field_of_studyMultidisciplinaryMiddle Eastbusiness.industryGenetic VariationAgricultureDNAEmigration and ImmigrationMitochondrialEuropeHaplotypesAgricultureEthnologyFemalebusiness
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28-year incidence and time trends of childhood leukaemia in former East Germany compared to West Germany after German reunification: A study from the…

2021

Abstract Background The aetiology of childhood leukaemia is largely unknown. Analyses of geographical differences may enhance aetiologic insights. The reunification of Germany in 1990 provides a unique opportunity to evaluate incidence patterns and time trends in two merging countries with substantial lifestyle, social and socioeconomic differences. With this study we provide an extensive assessment of 28-year incidence patterns and temporal trends after the German reunification. Methods We identified all children diagnosed with a lymphoid leukaemia (LL) or acute myeloid leukaemia (AML) before the age of 15 years between 1991 and 2018 using the German Childhood Cancer Registry (N = 14,922),…

MaleCancer ResearchAdolescentEpidemiologyPopulationDiseaseGerman03 medical and health sciences0302 clinical medicineHumansMedicineRegistries030212 general & internal medicineChildeducationSocioeconomic statusChildhood Cancer Registryeducation.field_of_studybusiness.industryIncidenceIncidence (epidemiology)Germany WestInfant NewbornInfantlanguage.human_languageLeukemia LymphoidChildhood leukaemiaLeukemia Myeloid AcuteOncologyChild Preschool030220 oncology & carcinogenesislanguageEtiologyFemaleGermany EastbusinessDemographyCancer Epidemiology
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Temporal trends in the incidence rate of childhood cancer in Germany 1987-2004.

2007

The German Childhood Cancer Registry regularly presents graphs of childhood cancer incidence rates by period, but no systematic analysis. The Automated Childhood Cancer Information System-project found an increasing trend in Europe. Against this background we present the first detailed trend analysis of childhood (aged under 15) malignancies in Germany. We examined incidence rates separately in western Germany 1987-2004 and eastern Germany 1991-2004. We analyzed all malignancies, all main diagnostic groups and relevant subsets using an age-period-cohort model. Additionally we fitted fractional polynomials to assess the linearity of the drift. All malignancies combined (excluding Central Ner…

MaleCancer ResearchPediatricsmedicine.medical_specialtyAdolescentLymphomaCentral Nervous System NeoplasmsGermanyNeoplasmsEpidemiologymedicineHumansRegistriesChildChildhood Cancer RegistryLeukemiabusiness.industryIncidence (epidemiology)IncidenceGermany WestCancerPrecursor Cell Lymphoblastic Leukemia-Lymphomamedicine.diseaseTrend analysisOncologyEl NiñoCohort effectChild PreschoolFemaleGermany EastGerm cell tumorsbusinessInternational journal of cancer
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Cross-cultural comparisons of child-reported emotional and physical abuse: rates, risk factors and psychosocial symptoms

2002

Abstract Objectives: This study was designed to assess the incidence of child emotional and physical abuse, associated risk factors and psychosocial symptoms in a cross-cultural comparison between post-communist bloc countries. Method: One-thousand one-hundred forty-five children ages 10–14 from Latvia (N=297), Lithuania (N=300), Macedonia (N=302), and Moldova (N=246) participated in the study. They completed questionnaires assessing their experience of emotional or physical abuse, and provided information about family risk-factors and psychosocial symptoms, including PTSD-related symptoms. Results: Incidence rates of maltreatment differed by country, as did levels of reported psychosocial …

MaleChild abusemedicine.medical_specialtySelf DisclosureAdolescentmedia_common.quotation_subjectPoison controlAlcohol abuseAngerStress Disorders Post-TraumaticRisk FactorsSurveys and QuestionnairesDevelopmental and Educational PsychologymedicineHumansPsychologyChild AbuseEurope EasternChildPsychiatryPsychological abusemedia_commonIncidenceCultural Diversitymedicine.diseasePsychiatry and Mental healthPhysical abusePediatrics Perinatology and Child HealthSelf-disclosureFemalePsychologyPsychosocialClinical psychologyChild Abuse & Neglect
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Human Y-chromosome variation in the Western Mediterranean area: Implications for the peopling of the region

2001

Y-chromosome variation was analyzed in a sample of 1127 males from the Western Mediterranean area by surveying 16 biallelic and 4 multiallelic sites. Some populations from Northeastern Europe and the Middle East were also studied for comparison. All Y-chromosome haplotypes were included in a parsimonious genealogic tree consisting of 17 haplogroups, several of which displayed distinct geographic specificities. One of the haplogroups, HG9.2, has some features that are compatible with a spread into Europe from the Near East during the Neolithic period. However, the current distribution of this haplogroup would suggest that the Neolithic gene pool had a major impact in the eastern and central …

MaleImmunologyMediterranean BasinHaplogroupGene flowMiddle Eastwest mediterranean basinAfrica NorthernY ChromosomeGenetic variationHumansImmunology and Allergyy-chromosome polymorphismsAllelesRecombination GeneticGeneticsPolymorphism GeneticMiddle EastMediterranean Regioneuropean populationsy-chromosome haplogroupsHaplotypeGenetic VariationGeneral MedicinehumanitiesEuropeGeographyHaplotypesEvolutionary biologyMultivariate AnalysisPeriod (geology)Gene poolgeographic locationseuropean populations; west mediterranean basin; y-chromosome haplogroups; y-chromosome polymorphismsMicrosatellite Repeats
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HUMAN HERPESVIRUS 8 SEROPREVALENCE AMONG INTERNATIONALLY ADOPTED CHILDREN COMING FROM EASTERN EUROPE

2009

The seroprevalence of Human Herpes Virus 8 (HHV8) and its transmission pattern were assessed testing serum samples of 120 internationally adopted children (aged 1-15 years) coming from Eastern Europe. Determinations of IgG antibodies against both latent and lytic HHV-8 antigens were performed by indirect immunofluorescence assay. Antibodies were detected only for lytic antigen of the virus in 12.5% of children with a seroprevalence significatively higher (19.6%) in young children (age 1-6). No correlation was observed between HHV8 seropositivity and serological markers for hepatitis A, B and C viruses and Human Immunodeficiency virus. In conclusion, our findings suggest that HHV8 infection …

MaleInternationalityAdopted children Eastern Europe Human Herpes Virus 8 Seroepidemiology .AdolescentInfantHIV InfectionsHerpesviridae InfectionsHepatitis AAntibodies ViralHepatitis BSettore MED/42 - Igiene Generale E ApplicataHepatitis CSeroepidemiologic StudiesChild PreschoolAdoptionHerpesvirus 8 HumanHumansFemaleEurope EasternChild
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tst1-positive ST22-MRSA-IVa in healthy Italian preschool children

2013

A survey was performed in May 2013 to assess methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization in healthy children attending 26 municipal daycare centres in Palermo, Italy. Of the 500 children, ten (2 %) tested positive. Eight MRSA isolates were tst1-positive ST22-MRSA-IVa, spa t223; the other two isolates were identified as ST1-IVa and ST398-V, respectively. tst1-positive ST22-MRSA, spa t223 has been previously identified only in the Middle Eastern area.

MaleMethicillin-Resistant Staphylococcus aureusMicrobiology (medical)Pediatricsmedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypeMEDLINEmedicine.disease_causeSettore MED/42 - Igiene Generale E ApplicataMolecular typingSettore MED/38 - Pediatria Generale E SpecialisticaGenotypemedicineHumansHealthy childrenNasal colonizationSicilyMolecular EpidemiologyMolecular epidemiologyMiddle Eastern areabusiness.industryData CollectionGeneral MedicineStaphylococcal Infectionsbiochemical phenomena metabolism and nutritionbacterial infections and mycosesST22-MRSA-IVaMolecular TypingInfectious DiseasesStaphylococcus aureusChild PreschoolCarrier StateDaycare centerFemalebusiness
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Tracing the genetic origin of Europe’s first farmers reveals insights into their social organization

2014

Farming was established in Central Europe by the Linearbandkeramik culture (LBK), a well-investigated archaeological horizon, which emerged in the Carpathian Basin, in today's Hungary. However, the genetic background of the LBK genesis has not been revealed yet. Here we present 9 Y chromosomal and 84 mitochondrial DNA profiles from Mesolithic, Neolithic Starčevo and LBK sites (7th/6th millennium BC) from the Carpathian Basin and south-eastern Europe. We detect genetic continuity of both maternal and paternal elements during the initial spread of agriculture, and confirm the substantial genetic impact of early farming south-eastern European and Carpathian Basin cultures on Central European p…

MaleMitochondrial DNAmedia_common.quotation_subjectMolecular Sequence DataPannonian basinPopulationBiologySocial EnvironmentDNA MitochondrialGeneral Biochemistry Genetics and Molecular BiologyStone AgeHumansSocial BehavioreducationSocial organizationResearch ArticlesMesolithicGeneral Environmental Sciencemedia_commoneducation.field_of_studyGenetic diversityChromosomes Human YFarmersMiddle EastGeneral Immunology and MicrobiologyHorizon (archaeology)ancient DNA; mitochondrial DNA; Y chromosomal DNA; Neolithization; Carpathian Basin; Central Europebusiness.industryGenetic VariationAgricultureSequence Analysis DNAGeneral MedicineEmigration and ImmigrationhumanitiesEuropeAncient DNAGeographyArchaeologyAgricultureEthnologyFemaleGeneral Agricultural and Biological SciencesbusinessDiversity (politics)
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Are food intolerances and allergies increasing in immigrant children coming from developing countries ?

2006

There are not available data concerning the occurrence, the clinical features and the environmental risk factors for food intolerances and allergies in immigrant children. The aim of the study was to evaluate rates, distribution, clinical features and environmental risk factors for food intolerances and allergies in immigrant children. Hospital records of 4,130 patients with celiac disease (CD), cow milk protein intolerance (CMPI) and food allergies (FA) diagnosed in 24 Italian Centres from 1999 to 2001 were retrospectively reviewed, comparing immigrant patients with Italian ones. 78/4,130 (1.9%) patients were immigrant: 36/1,917 (1.9%) had CD, 24/1,370 (1.75%) CMPI and 18/843 (2.1%) FA. Th…

MalePediatricsmedicine.medical_specialtyAdolescentmedia_common.quotation_subjectImmunologyImmigrationPopulationEthnic groupDeveloping countryDiseaseallergieMiddle EastIntolerancesFood allergyEnvironmental healthmedicineHumansImmunology and AllergyEurope Easternfood intoleranceChildeducationDeveloping CountriesAsia SoutheasternRetrospective Studiesmedia_commoneducation.field_of_studybusiness.industryInfantfood intolerances and allergieEmigration and ImmigrationSouth Americaimmigrant childrenmedicine.diseaseFood intoleranceCeliac DiseaseCross-Sectional StudiesItalyChild PreschoolAfricaPediatrics Perinatology and Child HealthFemaleMilk HypersensitivitybusinessFood Hypersensitivity
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Immunization status of internationally adopted children in Italy

2006

An increasing number of internationally adopted children is coming to Italy, and their immunization status is unknown. We evaluated the immunization status of such children in Palermo, Italy. We searched for the presence of a BCG scar in 88 children, 49 boys and 39 girls (mean age 76+/-32 months), most of whom (98%) came from Eastern Europe. Presence of BCG scar was observed in 59 (67.1%) of them, included five children without any pre-adoptive medical records. Twenty-three out of 29 children without any evidence of BCG scar were tested by Mantoux. Seven (30.4%) of 23 were tuberculin positive and diagnosed as having latent tuberculosis infection. We also examined immunization status against…

MalePediatricsmedicine.medical_specialtyHealth StatusTuberculinAntibodies ViralMeaslesRubellaMedical RecordsAdoptionmedicineHumansEurope EasternChildVaccinesGeneral VeterinaryGeneral Immunology and MicrobiologyLatent tuberculosisTuberculin TestTetanusbusiness.industryDiphtheriaImmunization.Public Health Environmental and Occupational HealthInfantEmigration and ImmigrationHepatitis Bmedicine.diseaseAntibodies BacterialAdopted childrenInfectious DiseasesItalyImmunizationChild PreschoolImmunologyBCG VaccineMolecular MedicineFemaleImmunizationbusinessVaccine
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