Search results for " Expo"

Surface-induced ordering and disordering in face-centered-cubic alloys: A Monte Carlo study

1996

Using extensive Monte Carlo simulations we have studied phase transitions in a fcc model with antiferromagnetic nearest-neighbor couplings $J$ in the presence of different free surfaces which lead either to surface-induced order or to surface-induced disorder. Our model is a prototype for CuAu-type ordering alloys and shows a strong first-order bulk transition at a temperature $\frac{k{T}_{\mathrm{cb}}}{|J|}=1.738005(50)$. For free (100) surfaces, we find a continuous surface transition at a temperature ${T}_{\mathrm{cs}}g{T}_{\mathrm{cb}}$ exhibiting critical exponents of the two-dimensional Ising model. Surface-induced ordering occurs as the temperature approaches ${T}_{\mathrm{cb}}$ and …

A new boundary-controlled phase transition: Phase separation in an Ising bi-pyramid with competing surface fields

2005

We study phase coexistence of an Ising ferromagnet in a bi-pyramid geometry with a square basal plane of linear extension 2L + 1. Antisymmetric surface fields act on the pyramid surfaces above and below the basal plane. In the limit L → ∞, the magnetisation stays zero at the bulk critical temperature, but becomes discontinuously non-zero at the cone filling critical temperature associated with a single pyramid. Monte Carlo simulations and scaling considerations show that this transition is described by a Landau theory with size-dependent coefficients that give rise to singular critical amplitudes.

Karyopherin Msn5 is involved in a novel mechanism controlling the cellular level of cell cycle regulators Cln2 and Swi5

2019

ABSTRACT The yeast β-karyopherin Msn5 controls the SBF cell-cycle transcription factor, responsible for the periodic expression of CLN2 cyclin gene at G1/S, and the nuclear export of Cln2 protein. Here we show that Msn5 regulates Cln2 by an additional mechanism. Inactivation of Msn5 causes a severe reduction in the cellular content of Cln2. This occurs by a post-transcriptional mechanism, since CLN2 mRNA level is not importantly affected in asynchronous cultures. Cln2 stability is not significantly altered in msn5 cells and inactivation of Msn5 causes a reduction in protein level even when Cln2 is stabilized. Therefore, the reduced amount of Cln2 in msn5 cells is mainly due not to a higher …

Regulation of cell cycle transcription factor Swi5 by karyopherin Msn5

2012

AbstractInactivation of S. cerevisiae β-karyopherin Msn5 causes hypersensitivity to the overexpression of mitotic cyclin Clb2 and aggravates growth defects of many mutant strains in mitotic exit, suggesting a connection between Msn5 and mitotic exit. We determined that Msn5 controlled subcellular localization of the mitotic exit transcription factor Swi5, since it was required for Swi5 nuclear export. Msn5 physically interacted with the N-terminal end of Swi5. Inactivation of Msn5 caused a severe reduction in cellular levels of Swi5 protein. This effect occurred by a post-transcriptional mechanism, since SWI5 mRNA levels were not affected. The reduced amount of Swi5 in msn5 mutant cells was…

Translocation Biosensors – Cellular System Integrators to Dissect CRM1-Dependent Nuclear Export by Chemicogenomics

2009

Fluorescent protein biosensors are powerful cellular systems biology tools for dissecting the complexity of cellular processes with high spatial and temporal resolution. As regulated nucleo-cytoplasmic transport is crucial for the modulation of numerous (patho)physiological cellular responses, a detailed understanding of its molecular mechanism would open up novel options for a rational manipulation of the cell. In contrast to genetic approaches, we here established and employed high-content cellular translocation biosensors applicable for dissecting nuclear export by chemicogenomics. A431 cell lines, stably expressing a translocation biosensor composed of glutathione S-transferase, GFP and…

Source and Nature of Inhaled Atmospheric Dust from Trace Element Analyses of Human Bronchial Fluids

2011

International audience; Rapid volcanic eruptions quickly ejecting large amounts of dust provoke the accumulation of heavy metals in people living in surrounding areas. Analyses of bronchoalveolar lavage samples (BAL) collected from people exposed to the paroxysmal 2001 Etna eruption revealed a strong enrichment of many toxic heavy metals. Comparing the BAL to the dust composition of southeastern Sicily, we found that only V, Cr, Mn, Fe, Co, and U enrichment could be related to the volcanic event, whereas Ni, Cu, Cd, and Pb contents come from the dissolution of particles of anthropogenic origin. Furthermore, the nature of these inhaled anthropogenic particles was revealed by anomalous La and…

Effects of oenological tannins on aroma release and perception of oxidized and non-oxidized red wine: A dynamic real-time in-vivo study coupling sens…

2022

International audience; Addition of oenological tannins claims to have a positive impact on wine stability, protection from oxidation and likely sensory persistence. However, their role on red wine aroma during oxidation is controversial. The present study aims at investigating the effect of addition of oenological tannins on wine flavour (mainly aroma) before and after air exposure. Temporal Dominance of Sensations, a dynamic sensory evaluation, was coupled with a dynamic chemical measurement (nosespace analysis) using a Proton-Transfer-Reaction Mass-Spectrometer connected to the nasal cavity of 17 assessors. Results showed that the oxidation of a non-oaked Pinot Noir red wine decreases th…

La naranja que se exporta es el alimento del pueblo y las armas para la lucha contra el invasor extrangero

D'un taronger surten dues branques que agarren a un home -amb la creu gammada- pel coll i ho derroquen sobre unes mates. Entre l'home i l'arbre està l'escut d'Espanya

La ley castiga con la pena de muerte al saboteador de la economía nacional Cometen sabotage los que impiden que la mejor naranja se convierta en dine…

Figura de dona amb ales d'àngel i un llaurador oferint-li un penjoll de taronges. Entre l'home i la dona està l'escut d'Espanya

Relationships between early flavor exposure, and food acceptability and neophobia

2016

Revue; In the first section of this chapter, an overview of what is known about early flavor exposure, distinguishing between taste and flavor (aroma) exposure is provided. In the second section, we will describe what has been researched regarding the influence of early flavor exposure on the development of food preference, looking at prenatal exposure, exposure received in the context of milk feeding and exposure received in the context of complementary feeding. The third section is a description of what has been shown regarding the relationships between early flavor exposure and food neophobia. The chapter ended with a comment on likely future trends, and by a description of sources of fu…