Search results for " Expo"

Usefulness of biomarkers as intermediate endpoints in health risks posed by occupational lead exposure

2015

The article concerns potential harmful effects of exposure to lead. Although the occurrence of severe lead poisoning has receded in several countries, occupational exposure resulting in moderate and clinically symptomatic toxicity is still common. An earlier and precise characterization of an individual response is obligatory in order to assess the possible risks for human health. Biomarkers may fill important gaps in the path from exposure to a disease. Specifically speaking, emerging (DNA double strand breaks and telomeric DNA erosion) and validated (micronuclei induction and chromosomal aberrations) biomarkers of genotoxicity seem to provide evidence for the assessment of molecular and c…

El control de los roedores: revisión de los rodenticidas registrados en el ámbito de la sanidad ambiental en España

2004

Josefa Moreno Marí, Jesús López Ferrer y Ricardo Jiménez Peydró josefa (moreno@uv.es) Actualmente se precisa del empleo de los llamados rodenticidas, definidos como productos biocidas empleados para el control de roedores. En la reciente transposición de la Directiva de Biocidas a través del Real Decreto 1054/2002, los rodenticidas se incluyen en el Grupo Principal 3, Tipo de Producto 14. Se analiza la situación actual de los rodenticidas en el Registro Oficial de Plaguicidas. El estudio se ha realizado a partir de los datos que figuran en la base de datos del Registro Oficial de Plaguicidas de Uso en Salud Pública de España para los rodenticidas (ingredientes activos técnicos) y formulados…

Effect of energy density on liking and on caloric adjustment conditioning after sweet beverage exposure in children aged 8-11 y

2014

The contribution of sweet beverages to weight gain in children and adolescents is controversial. The present study was conducted to study, in 8-11 year-old children, the influence of energy conditioning on liking and on caloric adjustment after sweet beverages exposure. We also studied the stability of the conditioning effects after a period without exposure and an extinction period. Children (n = 44) were exposed to 2 flavored sweetened beverages: a high energy version (HE: 150kcal) and a no energy version (NE: 0kcal). During a 4-wk conditioning period, children were exposed either 2 or 7 times to each beverage. During a 3-wk stability period children were not exposed to any beverage. Duri…

Legitimations of Finnish education export–exploring the plurality of guiding principles

2021

This paper explores the legitimation of Finnish education export (EE) activities linked to higher education institutions. As a small non-English speaking country with only recent involvement in the EE market, Finland provides an underexplored context to consider the legitimation of overseas, fee-based educational services from the perspective of EE providers. In this qualitative case study comprising two Finnish EE endeavours, we draw on convention theory to argue that the legitimation of education export is based on multiple roles of such export, not just on generating revenue for the provider institution. We show that legitimations are linked to multiple guiding principles, illustrated in…

Binding of RNA Aptamers to Membrane Lipid Rafts: Implications for Exosomal miRNAs Transfer from Cancer to Immune Cells

2020

Intraluminal vesicles (ILVs) are released into the extracellular space as exosomes after the fusion of multivesicular bodies (MVBs) with the plasma membrane. miRNAs are delivered to the raft-like region of MVB by RNA-binding proteins (RBPs). RNA loading into exosomes can be either through direct interaction between RNA and the raft-like region of the MVB membrane, or through interaction between an RBP&ndash

Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies

2019

The distribution of amyloid beta peptide 42 (Aβ42) between model exosomal membranes and a buffer solution was measured. The model membranes contained liquid-ordered regions or phosphatidylserine. Results demonstrated that up to ca. 20% of amyloid peptide, generated in the plasma (or intracellular) membrane as a result of proteolytic cleavage of amyloid precursor proteins by β- and γ-secretases, can stay within the membrane milieu. The selection of RNA aptamers that bind to Aβ42 incorporated into phosphatidylserine-containing liposomal membranes was performed using the selection-amplification (SELEX) method. After eight selection cycles, the pool of RNA aptamers was isol…

Localization and dimension estimation of attractors in the Glukhovsky-Dolzhansky system

2016

UNCERTAINTY EVALUATION IN THE LOW-FREQUENCY MAGNETIC FIELD MEASUREMENTS WITH REGARD TO EXPOSURE OF HUMAN BEINGS

2010

The paper deals with low-frequency magnetic field measurements, with regard to exposure of human beings, carried out by using a broadband and isotropic instrument. These measurements are characterized by a very high uncertainty values if compared with the ones usually related to other electrical measurements. These large uncertainty values imply a high risk of wrong decision when there is the need to establish if a site complies or does not comply with a specified emission limits. A reduction of the uncertainty values implies a reduction of the risk. With this aim, in the paper we propose an approach which, in case of fields generated by electric power systems (50 or 60 Hz), allows an effec…

Lyapunov quantities and limit cycles in two-dimensional dynamical systems : analytical methods, symbolic computation and visualization

2011

Internal resources as tools to increase the global competition: the Italian wine industry case

2017

Purpose The purpose of this paper is twofold: first, it identifies distinct organizational models in a sample of small and medium enterprises operating in the Sicilian wine industry; and second, it identifies the key factors enabling a superior export success. Design/methodology/approach Internal resources were analyzed theoretically in order to achieve the aims of the study. Subsequently the empirical investigation was carried out administering a questionnaire to a sample of 102 wineries in Sicily, Italy. A cluster analysis was performed in order to group these firms into homogeneous categories. Findings The findings show that success in the international market is more common among winer…