Search results for " Formation"
showing 10 items of 1920 documents
Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus
2013
Type 1 cannabinoid receptor (CB1) is expressed in different neuronal populations in the mammalian brain. In particular, CB1 on GABAergic or glutamatergic neurons exerts different functions and display different pharmacological properties in vivo. This suggests the existence of neuron-type specific signalling pathways activated by different subpopulations of CB1. In this study, we analysed CB1 expression, binding and signalling in the hippocampus of conditional mutant mice, bearing CB1 deletion in GABAergic (GABA-CB1-KO mice) or cortical glutamatergic neurons (Glu-CB1-KO mice). Compared to their wild-type littermates, Glu-CB1-KO displayed a small decrease of CB1 mRNA amount, immunoreactivity…
Role of two co-occurring Mediterranean sea urchins in the formation of barren from Cystoseira canopy
2015
Abstract In the Mediterranean Sea the co-occurring sea urchins Paracentrotus lividus and Arbacia lixula are usually considered to share the same ecological role in the formation of barren from Cystoseira canopy. However, their foraging ability may vary due to feeding behavior and species-specific morphological traits. The relative effects of P. lividus and A. lixula on Cystoseira canopy was tested experimentally both in the laboratory, at a density of about 20 ind./m 2 , and in the field by gut content analysis. Field and laboratory results show that A. lixula is unable to affect Cystoseira spp. Furthermore, these results confirmed the great ability of P. lividus to consume Cystoseira canop…
Education, capital humain et dynamique économique : analyse à partir du secteur industriel sénégalais
2005
The objective of this work is to analyze the relations between education, human capital and the industrial performances in Senegal. The approached questions are different and varied, and more particularly, they relate to the investment of industrial concerns in the human resources (levels of qualification of the workforce, training policies), at the various levels of efficiency (internal and external) of the educational system, in the adequacy training / employment, etc. The impact of the human capital investment of the firms on their own performances is finally studied.
N'est pas indépendant qui veut ! : Analyse des processus de fermeture dans l'accès à l'emploi
2010
Les notes de l'IREDU, n°10/01, mai 2010; Les analyses sociologiques ou économiques considèrent les professions indépendantes généralement au travers d'approches sectorielles (la santé, le droit, l'artisanat.) ou de travaux ethnographiques à partir d'une profession précise. Cette recherche propose un cadre théorique qui analyse de façon plus globale le marché de l'emploi des professions indépendantes. Elle s'intéresse plus précisément aux systèmes de légitimation qui permettent à une activité de s'exprimer dans un cadre professionnel, tout en minimisant les possibilités d'existence de formes alternatives concurrentes susceptibles d'affaiblir leur statut et les privilèges associés. Après avoi…
Analyse des processus de fermeture dans l'accès à l'emploi
2009
Les cahiers de l'IREDU, n°70, 182 p.; Les analyses sociologiques ou économiques considèrent les professions indépendantes généralement au travers d'approches sectorielles (la santé, le droit, l'artisanat.) ou de travaux ethnographiques à partir d'une profession précise. Cette recherche propose un cadre théorique qui analyse de façon plus globale le marché de l'emploi des professions indépendantes. Elle s'intéresse plus précisément aux systèmes de légitimation qui permettent à une activité de s'exprimer dans un cadre professionnel, tout en minimisant les possibilités d'existence de formes alternatives concurrentes susceptibles d'affaiblir leur statut et les privilèges associés. Après avoir p…
Microstructure-specific carbon isotopic signatures of organic matter from ∼3.5 Ga cherts of the Pilbara Craton support a biologic origin.
2016
21 pages; International audience; The ∼3.5 Ga Dresser Formation from the North Pole Dome of the Pilbara Craton (Western Australia) contains some of the oldest evidence for life on Earth. Here, we present a detailed study of microstructure-specific carbon isotopic composition of organic matter (OM) preserved in Dresser Formation bedded cherts and hydrothermal chert vein using in situ Secondary-Ion Mass Spectrometry (SIMS). The OM in these rocks occurs mainly as clots that, together with minor fine OM layers and laminae, are considered primary textures formed prior to host rock lithification. Other than rare OM-rich stylolites, no evidence was found for later OM migration beyond the micromete…
Late Carnian-Early Norian ammonoids from the GSSP candidate section Pizzo Mondello (Sicani mountain, Sicily).
2012
A small collection of ammonoids from the Upper Triassic Scillato Formation at Pizzo Mondello (Agrigento, Sicily) is studied. The specimens were collected in a framework of a project aimed at providing an integrated high-resolution bio-chronostratigraphic support to the Upper Carnian-Norian magnetostratigraphic scale defined at this site, that is located in an historical area from which G.G. Gemmellaro collected the Upper Triassic of ammonoids monographed at the beginning of the XX century. The specimens from Pizzo Mondello were bed-by-bed sampled and represent the first collection of Upper Triassic ammonoids described from Sicily since Gemmellaro time. Quite several levels of the Pizzo Mond…
Antibody generation and immunoassay development in diverse formats for pyrimethanil specific and sensitive analysis
2012
Immunochemical techniques are complementary tools to modern analytical requirements. These methods rely on the production of immunoreagents with adequate binding properties. In the present study, a rationally designed and functionalized derivative of pyrimethanil-a modern anilinopyrimidine fungicide-was synthesized in order to generate for the first time high-affinity and selective antibodies to this xenobiotic. A single coupling procedure-based on hapten activation using N,N′-disuccinimidyl carbonate and purification of the active ester-was followed to prepare both immunizing and assay conjugates. Polyclonal antibodies were produced and characterized by enzyme-linked immunosorbent assay (E…
Accumbens-caudate-septal circuit as a system for hippocampal regulation: involvement of a GABAergic neurotransmission.
1992
Hippocampal-based epileptiform activity may reach the basal ganglia via the nucleus accumbens. Previous data suggested that caudate nucleus is able to influence hippocampal epilepsy, probably sending a projection to the septum. In order to test the hypothesis of a retrograde activation of accumbens-caudate pathway in hippocampal regulation, we electrically stimulated both caudate nucleus and nucleus accumbens and studied modifications of hippocampal EEG in the feline focal epilepsy model. We also performed bilateral electrolytic lesion of nucleus accumbens and repeated caudate stimulation. Results showed that nucleus accumbens stimulation was ineffective in modifying hippocampal epilepsy; o…
Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells
2009
For successful bone regeneration tissue engineered bone constructs combining both aspects, namely a high osteogenic potential and a rapid connection to the vascular network are needed. In this study we assessed the formation of pre-vascular structures by human outgrowth endothelial cells (OEC) from progenitors in the peripheral blood and the osteogenic differentiation of primary human osteoblasts (pOB) on micrometric silk fibroin scaffolds. The rational was to gain more insight into the dynamic processes involved in the differentiation and functionality of both cell types depending on culture time in vitro. Vascular tube formation by OEC was assessed quantitatively at one and 4 weeks of cul…