Search results for " Function"

showing 10 items of 9395 documents

Restoring Neurological Physiology: The Innovative Role of High-Energy MR-Guided Focused Ultrasound (HIMRgFUS). Preliminary Data from a New Method of …

2017

Background Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultra-sound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation. Methods At the Neurosurgical Clinic and the Radiology Department of the University of Palermo,, tw…

medicine.medical_specialtyParkinson's diseaseDeep brain stimulationmedicine.medical_treatmentNeurosurgical ProcedureSeverity of Illness IndexNeurosurgical ProceduresFocused ultrasoundMRI-guided focused ultrasound (MRgFUS)03 medical and health sciences0302 clinical medicineTremormedicineHumans030212 general & internal medicineResting tremorVentral Thalamic Nucleimedicine.diagnostic_testEssential tremorSettore MED/27 - Neurochirurgiabusiness.industryEssential tremor; functional neurosurgery; lesioning surgery; MRI-guided focused ultrasound (MRgFUS); Parkinson’s disease; brain; high-intensity focused ultrasound ablation; humans; magnetic resonance imaging; neurosurgical procedures; severity of illness index; surgery computer-assisted; tremor; ventral thalamic nucleiSettore MED/37 - NeuroradiologiaBrainMagnetic resonance imagingLesioning surgerymedicine.diseaseMagnetic Resonance ImagingNeuromodulation (medicine)nervous system diseasesSurgerySubthalamic nucleusFunctional neurosurgerySurgery Computer-AssistedParkinson’s diseaseEssential tremorHigh-Intensity Focused Ultrasound AblationSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness030217 neurology & neurosurgeryHuman
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Neurophysiological evaluation of visual function in iRBD: potential role in stratifying RBD conversion risk.

2021

Abstract Study objectives To evaluate neurophysiological alterations of visual function in idiopathic REM sleep Behavior Disorder (iRBD) both as markers and predictors of neurodegenerative disorders. Methods In a longitudinal follow-up study of 46 consecutive iRBD patients (follow-up duration 8.4 ± 3.4 years), the baseline parameters in luminance-contrast pattern (VEPp), red-green color (VEPc) and motion-onset (VEPm) Visual Evoked Potentials in iRBD were compared to early (ePD) and advanced (aPD) Parkinson's Disease subjects. Parameters of latency and amplitude of iRBD converters to neurodegenerative disease were compared with those of the non-converters. Results The VEP P100 mean latency v…

medicine.medical_specialtyParkinson's diseasegenetic structuresEvoked potentials; Neurodegenerative disorders; Neurophysiology; Parkinson's disease; Phenoconversion risk; REM sleep Behavior disorderParkinson's diseaseNeurophysiologyVisual evoked potentialsREM Sleep Behavior DisorderAudiologyREM sleep behavior disorder03 medical and health sciences0302 clinical medicinemedicineHumansbusiness.industryNeurodegenerative DiseasesParkinson DiseaseGeneral MedicineEvoked potentialsNeurophysiologymedicine.disease030228 respiratory systemVisual functionNeurodegenerative disordersEvoked Potentials VisualPhenoconversion riskbusiness030217 neurology & neurosurgeryFollow-Up StudiesSleep medicine
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Liver Function Test Abnormalities in Patients with Inflammatory Bowel Diseases: A Hospital-based Survey

2014

Background and Aims Inflammatory bowel diseases (IBD) are frequently associated with altered liver function tests (LFTs). The causal relationship between abnormal LFTs and IBD is unclear. The aim of our study was to evaluate the prevalence and etiology of LFTs abnormalities and their association with clinical variables in a cohort of IBD patients followed up in a single center. Materials and Methods A retrospective review was undertaken of all consecutive IBD in- and outpatients routinely followed up at a single referral center. Clinical and demographic parameters were recorded. Subjects were excluded if they had a previous diagnosis of chronic liver disease. LFT abnormality was defined as …

medicine.medical_specialtyPathologySettore MED/09 - Medicina Internadrug-induced hepatotoxicityChronic liver diseaseInflammatory bowel diseaseGastroenterologyCholestasisinflammatory bowel diseaseInternal medicinemedicinelcsh:RC799-869Original Researchfatty liverLiver injurymedicine.diagnostic_testbusiness.industryFatty liverGastroenterologymedicine.diseaseCohortEtiologylcsh:Diseases of the digestive system. Gastroenterologyliver function testsbusinessLiver function testsClinical Medicine Insights: Gastroenterology
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Temporary warm ischaemia, 5/6 nephrectomy and single uranylnitrate administration — comparison of three models intended to cause renal fibrosis in ra…

2001

In patients the progression of pathologic renal processes after the treatment of primary disease is a problem of increasing importance and therapeutic strategies are insufficient till now. The aim of this paper was to search for rat models of interstitial fibrosis as a basis for testing therapeutic strategies to prevent end-stage renal failure. Experiments were done on adult female Wistar rats (Han:Wist) to investigate long-term consequences of temporary warm ischaemia, 5/6 nephrectomy (5/6 NX) and single uranyl nitrate (UN) administration (0.3 or 0.5 mg/ 100 g body wt. intraperitoneally). Observation time was 20 weeks after injury in each group. Creatinine clearance, urinary protein excret…

medicine.medical_specialtyPathologyTime Factorsmedicine.medical_treatmentUrologyRenal functionKidneyToxicologyNephrectomyPathology and Forensic MedicineExcretionFibrosismedicineRenal fibrosisAnimalsRats WistarKidneybusiness.industryKidney metabolismCell BiologyGeneral Medicinemedicine.diseaseFibrosisNephrectomyRatsDisease Models AnimalHydroxyprolineProteinuriamedicine.anatomical_structureCreatinineReperfusion InjuryUranyl NitrateNephritis InterstitialFemalebusinessKidney diseaseExperimental and Toxicologic Pathology
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Satisfaction levels of patients and their families with a Psychiatric Hospital Unit.

2012

Title: Satisfaction levels of patients and their families with a Psychiatric Hospital Unit. Abstract: In recent decades there has been growing interest in examining patient satisfaction since it can have great influence on the patients' adher- ence to treatment and their clinical evolution. Similarly, it has been demonstrated that the satisfaction of psychiatric patients is an indicator of the quality of mental health services. It has also been demonstrated that it is a strong predictor of the future use that psychiatric patients will make of these services and their willingness to cooperate with treatment. In Spain, there have been few studies conducted on patient satisfaction in Spanish p…

medicine.medical_specialtyPatient satisfactionTreatment planmedicinePsychiatric hospitalPsychiatryPsychologyMental illnessmedicine.diseaseMental healthCompetence (human resources)General PsychologySocial functioningAnales de Psicología
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966 The Nonthyroidal Illness Syndrome in Septic Children

2012

Backgroud The interpretation of thyroid function tests in the PICU patients can be difficult because thyroid hormone concentrations are affected by nonthyroidial stresses. Most patients fall into sick euthyroid syndrome or nonthyroidal illness syndrome (NTIS). The TH therapy during critical illness remains controversial. Aim To evaluate the NTIS in septic children. Method The prospective study conducted on 65 patients admitted in PICU during 12 months period. Inclusion criteria: age > 1 month, admission for critical illness, treatment with corticosteroids, no (documented) history of thyroid pathology. The patients were divided into 2 groups: sepsis and non-sepsis group (dehydration, poisoni…

medicine.medical_specialtyPediatricsmedicine.diagnostic_testbusiness.industryThyroidmedicine.diseaseThyroid function testsSepsisMalnutritionmedicine.anatomical_structurePediatrics Perinatology and Child HealthmedicineSick Euthyroid SyndromeThyroid functionbusinessIntensive care medicineProspective cohort studyHormoneArchives of Disease in Childhood
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Results of the smooth-muscle fold-over double-plasty (SMFD)

1986

Since 1980, when we developed substitute for the internal anal sphicter, the smooth-muscle fold-over double-plasty (SMFD-plasty), we have operated on seven children using this method, usually in combination with the pull-through procedure, and on five children after one or more previous operations. Since 1983, 11 cases with previous operations have undergone the modified “door-wing” SMFD-plasty. The results are excellent if the operation is used in primary combination with the pull-through procedure or if the “door-wing” modification is combined with reconstruction of the pelvic floor. It is also necessary that all cases undergo a biofeedback conditioning program.

medicine.medical_specialtyPelvic floorAnorectal diseaseFold (higher-order function)business.industryGeneral MedicineAnusSurgerymedicine.anatomical_structureSmooth musclePediatrics Perinatology and Child HealthBiofeedback conditioningmedicineSurgeryAnal sphincterbusinessPediatric Surgery International
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SUBFRACTIONS AND SUBPOPULATIONS OF HDL: AN UPDATE

2014

High-density lipoproteins (HDL) are classified as atheroprotective because they are involved in transport of cholesterol to the liver, known as "reverse cholesterol transport (RCT)" exerting antioxidant and anti-inflammatory activities. There is also evidence for cytoprotective, vasodilatory, antithrombotic, and anti-infectious activities for these lipoproteins. HDLs are known by structural, metabolic and biologic heterogeneity. Thus, different methods are able to distinguish several subclasses of HDL. Different separation techniques appear to support different HDL fractions as being atheroprotective or related with lower cardiovascular (CV) risk. However, HDL particles are not always prote…

medicine.medical_specialtyPharmacologyBiologySystemic inflammationBiochemistrychemistry.chemical_compoundRisk FactorsInternal medicineDrug DiscoveryAntithromboticmedicineAnimalsHumansHdl functionalityPharmacologyCholesterolOrganic ChemistryReverse cholesterol transportBiomarker (cell)EndocrinologychemistryCardiovascular DiseasesMolecular MedicineSeparation methodlipids (amino acids peptides and proteins)Hdl subfractionscardiovascular risk electrophoresis high-density lipoprotein nuclear magnetic resonance proteome subclasses subfractions ultracentrifugation.medicine.symptomLipoproteins HDL
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Beneficial Effects of Inspiratory Muscle Training Combined With Multicomponent Training in Elderly Active Women

2019

ABSTRACTPurpose: This study aims to analyze changes in Maximum Inspiratory Pressure (MIP), lung function, cardiorespiratory fitness, and blood pressure, in 10 healthy active elderly women, followin...

medicine.medical_specialtyPhysical fitnessBlood Pressure030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationPhysical strengthBreathing Exercises03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationHumansMedicineOrthopedics and Sports MedicineMuscle StrengthCardiovascular fitnessBeneficial effectsLung functionAgedbusiness.industryInspiratory muscle trainingCardiorespiratory fitness030229 sport sciencesGeneral MedicineRespiratory MusclesBlood pressureCardiorespiratory FitnessInhalationNephrologyFemalesense organsbusinessPhysical Conditioning HumanResearch Quarterly for Exercise and Sport
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Tiotropium (SpirivaÒ RespimatÒ ) Improves Physical Functioning In COPD Patients

2010

medicine.medical_specialtyPhysical functioningbusiness.industryCopd patientsPhysical therapymedicinebusinessC42. CHRONIC OBSTRUCTIVE PULMONARY DISEASE PHARMACOLOGIC INTERVENTIONS AND OUTCOMES
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