Search results for " Genome sequencing"

showing 10 items of 161 documents

Genome Sequence of Lactobacillus plantarum 19L3, a Strain Proposed as a Starter Culture for Slovenská Bryndza Ovine Cheese

2014

ABSTRACT The genome sequence of Lactobacillus plantarum isolated from ovine cheese is presented here. This bacterium is proposed as a starter strain, named 19L3, for Slovenská bryndza cheese, a traditional Slovak cheese fulfilling European Food Safety Authority (EFSA) requirements.

Whole genome sequencingbiologybusiness.industryStrain (biology)biology.organism_classificationFood safetyMicrobiologyStarterGeneticsProkaryotesbusinessMolecular BiologyLactobacillus plantarumBacteriaGenome Announcements
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Genome Sequence of Klebsiella pneumoniae KpQ3, a DHA-1 β-Lactamase-Producing Nosocomial Isolate.

2012

ABSTRACT Klebsiella pneumoniae KpQ3 is a multidrug-resistant isolate obtained from a blood culture of a patient in a burn unit in the Hospital Universitario La Paz (Madrid, Spain) in 2008. The genome contains multiple antibiotic resistance genes, including a plasmid-mediated DHA-1 cephalosporinase gene.

Whole genome sequencingbiologymedicine.diagnostic_testKlebsiella pneumoniaebiology.organism_classificationGenomeMicrobiologyGeneticsmedicineBlood cultureProkaryotesMolecular BiologyGeneAntibiotic resistance genesGenome announcements
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NovelAmycolatopsis balhimycinabiochemical abilities unveiled by proteomics

2014

Amycolatopsis balhimycina DSM5908 is an actinomycete producer of balhimycin, an analogue of vancomycin, the antibiotic of ‘last resort’ against multidrug-resistant Gram-positive pathogens. Most knowledge on glycopeptide biosynthetic pathways comes from studies on A. balhimycina as this strain, among glycopeptide producers, is genetically more amenable. The recent availability of its genome sequence allowed to perform differential proteomic analyses elucidating key metabolic pathways leading to antibiotic production in different growth conditions. To implement proteomic data on A. balhimycina derived from 2-DE approaches and to identify novel components, a combined approach based on protein …

Whole genome sequencingchemistry.chemical_classificationSpectrometry Mass Electrospray Ionizationmass spectrometry; 1D-electrophoresis; glycopeptide antibiotics; actinomycetes; glutamate dehydrogenaseProteomeBiologyProteomicsMicrobiologyGenomeActinomycetes proteomics 2D-DIGE Mass spectrometryGlycopeptideSynthetic biologyMetabolic pathwayEnzymeBiochemistrychemistryBacterial ProteinsTandem Mass SpectrometryProtein purificationActinomycetalesGeneticsElectrophoresis Polyacrylamide GelMolecular BiologyMetabolic Networks and Pathways
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Deciphering the role of insertion sequences in the evolution of bacterial epidemic pathogens with panISa software

2020

Next-generation sequencing (NGS) is now widely used in microbiology to explore genome evolution and the structure of pathogen outbreaks. Bioinformatics pipelines readily detect single-nucleotide polymorphisms or short indels. However, bacterial genomes also evolve through the action of small transposable elements called insertion sequences (ISs), which are difficult to detect due to their short length and multiple repetitions throughout the genome. We designed panISa software for the ab initio detection of IS insertions in the genomes of prokaryotes. PanISa has been released as open source software (GPL3) available from https://github.com/bvalot/panISa. In this study, we assessed the utilit…

Whole genome sequencinginsertion sequence0303 health sciencesGenome evolutionPhylogenetic treeoutbreak030306 microbiologyGeneral MedicineBacterial genome sizeComputational biologyBiologybacterial evolutionGenomePathogenicity island03 medical and health sciences[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitologywhole-genome sequencing[SDE]Environmental SciencesInsertion sequenceIndelComputingMilieux_MISCELLANEOUS030304 developmental biology
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Complete Genome Sequence of a New Ruminococcaceae Bacterium Isolated from Anaerobic Biomass Hydrolysis

2018

ABSTRACT A new Ruminococcaceae bacterium, strain HV4-5-B5C, participating in the anaerobic digestion of grass, was isolated from a mesophilic two-stage laboratory-scale leach bed biogas system. The draft annotated genome sequence presented in this study and 16S rRNA gene sequence analysis indicated the affiliation of HV4-5-B5C with the family Ruminococcaceae outside recently described genera.

anaerobic digestion0301 basic medicine570Ruminococcaceae030106 microbiology610BiomassBiologyArticle03 medical and health sciencesHydrolysisBiogasbacterial genomeBotanyGeneticsProkaryotesMolecular BiologyWhole genome sequencingwhole genome sequencingnonhumanmicrobial biomassbacterial strain16S ribosomal RNAAnaerobic digestion030104 developmental biologyhydrolysisAnaerobic exerciseMesophileGenome Announcements
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Globin genes are present in Ciona intestinalis.

2003

The key position of the Ciona intestinalis basal to the vertebrate phylogenetic tree brings up the question of which respiratory proteins are used by the tunicate to facilitate oxygen transport and storage. The publication of the Ciona draft genome sequence suggests that globin genes are completely missing and that-like some molluscs and arthropods-the sea squirt uses hemocyanin instead of hemoglobin for respiration. However, we report here the presence and expression of at least four distinct globin gene/protein sequences in Ciona. This finding is in agreement with the ancestral phylogeny of the vertebrate globins. Moreover, it seems likely that the Ciona hemocyanin-like sequences have enz…

animal structuresMolecular Sequence DataGenomeEvolution MolecularPhylogeneticsGeneticsAnimalsCiona intestinalisGlobinAmino Acid SequenceMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyWhole genome sequencingGeneticsGenomebiologyPhylogenetic treeSequence Homology Amino AcidfungiOxygen transportAnatomybiology.organism_classificationCiona intestinalisGlobinsCionaembryonic structuresMolecular biology and evolution
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Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain

2020

This article belongs to the Special Issue Bacteriophage—Molecular Studies.

phage therapyPhage therapyPhage therapyKlebsiella pneumoniae<i>Klebsiella pneumoniae</i>medicine.medical_treatmentGenome ViralArticleHost SpecificityCatalysisMicrobiologylcsh:ChemistryInorganic ChemistryBacteriophageViral Proteins03 medical and health sciencesPodoviridaeProtein DomainsbacteriophagemedicineHumansBacteriophagesTypingPhysical and Theoretical ChemistryBacteriophagelcsh:QH301-705.5Molecular BiologyPhylogenySpectroscopy030304 developmental biologyWhole genome sequencingInfectivityLikelihood Functions0303 health sciencesbiology030306 microbiologyOrganic ChemistryGeneral Medicinebiology.organism_classification3. Good healthComputer Science ApplicationsKlebsiella pneumoniaelcsh:Biology (General)lcsh:QD1-999Lytic cycleSpainInternational Journal of Molecular Sciences
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Genome degeneration and adaptation in a nascent stage of symbiosis

2014

Symbiotic associations between animals and microbes are ubiquitous in nature, with an estimated 15% of all insect species harboring intracellular bacterial symbionts. Most bacterial symbionts share many genomic features including small genomes, nucleotide composition bias, high coding density, and a paucity of mobile DNA, consistent with long-term host association. In this study, we focus on the early stages of genome degeneration in a recently derived insect-bacterial mutualistic intracellular association. We present the complete genome sequence and annotation of Sitophilus oryzae primary endosymbiont (SOPE). We also present the finished genome sequence and annotation of strain HS, a close…

pseudogènePseudogene[SDV]Life Sciences [q-bio]Molecular Sequence DataIS elements;comparative genomics;degenerative genome evolution;pseudogenes;recent symbiontpseudogenesBacterial genome sizedegenerative genome evolutioncomparative genomicsBiologyGenomeIS elementsEvolution Molecular03 medical and health sciencesEnterobacteriaceaeGeneticsAnimalsdonnée de séquence moléculaireInsertion sequenceSymbiosisGeneEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS030304 developmental biology2. Zero hungerGeneticsComparative genomicsWhole genome sequencing0303 health sciencesBase Sequence030306 microbiologygénomique comparativeAdaptation PhysiologicalColeopterarecent symbiontAdaptationsymbiosedégradation du génomeGenome Bacterialséquence d'insertionResearch Article
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Data from: Genomics of speciation and introgression in Princess cichlid fishes from Lake Tanganyika

2016

How variation in the genome translates into biological diversity and new species originate has endured as the mystery of mysteries in evolutionary biology. African cichlid fishes are prime model systems to address speciation-related questions for their remarkable taxonomic and phenotypic diversity, and the possible role of gene flow in this process. Here, we capitalize on genome sequencing and phylogenomic analyses to address the relative impacts of incomplete lineage sorting, introgression and hybrid speciation in the Neolamprologus savoryi-complex (the ‘Princess cichlids’) from Lake Tanganyika. We present a time-calibrated species tree based on whole-genome sequences and provide strong ev…

recombination biasmedicine and health carewhole genome sequencingNeolamprologusMedicinegenomic landscapesLinked selectionhuman activitiesLife sciencesintrogressive hybridization
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Complete genome sequence of the methanogenic neotype strain Methanobacterium formicicum MF(T.).

2014

The neotype strain Methanobacterium formicicum MFT (DSM1535), a hydrogenotrophic methanogenic Archaeon, was isolated from a domestic sewage sludge digestor in Urbana (IL, USA). Here, the complete genome sequence of the methanogen is reported. The genome is 2,478,074 bp in size, featuring a GC content of 41.23%. M. formicicum MFT encodes several genes predicted to be involved in adaptation to abiotic stress such as high osmolarity. The strain MFT is of biotechnological importance since M. formicicum strains are often found in production-scale biogas plants and it is suggested as a starter culture for the anaerobic biomethanation process. (C) 2014 Elsevier B.V. All rights reserved.

synthesisMethanogenesisMolecular Sequence DataBioengineeringMethanogenesisApplied Microbiology and BiotechnologyGenomeWaste Disposal FluidMicrobiologyGeneWhole genome sequencingStrain (chemistry)biologyInoculant cultureBase SequenceMethanobacteriumCompatible soluteGeneral MedicineSequence Analysis DNAbiology.organism_classificationBiogas productionMethanogenMethaneGC-contentSludgeGenome BacterialBiotechnologyJournal of biotechnology
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