Search results for " Guide"

Building composite indicators in tourism studies: Measurements and applications in tourism destination competitiveness

2017

Abstract Composite indicators are useful tools to synthesize and monitor multidimensional phenomena. The aim of this paper is twofold: to offer the methodological foundations to build composite indicators in tourism and to evaluate a set of currently available composite indicators. Tourism destination competitiveness indicators constitute the object of this contribution. Their definitions, concepts and measures are analyzed and their evaluation is performed through the application of an original protocol. The results highlight that several methodological issues still surround the measurement of destinations competitiveness indicators. This paper provides tourism scholars and practitioners w…

Kehityksellinen kielihäiriö (kielellinen erityisvaikeus, lapset ja nuoret) : Käypä hoito -suositus

2019

Antinociceptive Effects of Turkish Endemic Eryngium kotschyi Boiss. Roots by Bioactivity Guided Fractionation

2010

Eryngium species (Apiaceae) are well known plants in ethnobotanical culture throughout world and also in Turkey. They are used as antitussive, diuretic as well as for analgesic and antiinflammatory purposes in traditional medicine. This study aimed to evaluate the antinociceptive activity of endemic Eryngium kotschyi Boiss. root extracts by bioguided fractionation. The antinociceptive activity of the extracts/fractions/compound was studied in mice using acetic acid induced writhing test and and hot plate test. The methanolic extract was sequentially partitioned with hexane, dichloromethane and water saturated n-butanol. Among the fractions, the n-BuOH fraction showed the most significant re…

Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diab…

2017

Aims These recommendations aim to improve care for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk in Central and Eastern Europe. Cardiovascular disease (CVD) and/or chronic kidney disease (CKD) are major interdependent comorbidities in patients with T2D, accounting for 50% of mortality. Following recent CV outcomes trial (CVOT) results, including those from EMPA-REG OUTCOME®, LEADER®, SUSTAIN™-6 and, most recently, the CANVAS study, it is essential to develop regional expert consensus recommendations to aid physicians in interpreting these newest data to clinical practice. Methods The Central and Eastern European Diabetes Expert Group (CEEDEG) followed a Delphi method …

Blood Transfusion Management for Patients Treated With Anti-CD38 Monoclonal Antibodies

2018

Daratumumab has proven to be highly efficacious for relapsed and refractory multiple myeloma (MM) and has recently been approved in the frontline setting for MM patients ineligible for transplantation. In the future, expanded indications are possible for daratumumab and other anti-CD38 monoclonal antibodies in development. For several years, it has been recognized that these therapies interfere with blood bank testing by binding to CD38 on red blood cells and causing panagglutination on the Indirect Antiglobulin Test. This can lead to redundant testing and significant delays in patient care. Given the anticipated increase in utilization of anti-CD38 monoclonal antibodies, as well as the tra…

A BRIEF DISSECTION GUIDE TO HUMAN THORAX

2020

The purpose of this technical report is to present the experience that, in summer 2018, a group of students from the University of Palermo did at the University of Malta. The students have had the experience to dissected a thorax under the guide of expert dissectors. This work would be also a small dissection guide for young medical students who want to learn the main bases of dissection.

STRATIFICATION TECHNIQUE OF A NANOCOMPOSITE USING THE SILICON GUIDE

2015

At present, the stratification technique of composite materials, known as offering most predictable, both functional and aesthetic results, uses a silicone reference quide. This allows the dentist to appreciate the size and thickness of the composite resin layer to be applied, as well as selection of the opacity and translucidity degree according to the reconstructed enamel or dentin structure, thus facilitating the stratification of materials. The minimum adjustment, at the level of the palatal wall, represents another great advantage of the silicone key.

Noninvasive Ventilation in Critically Ill Patients

2015

Since its first application in the late 1980s, noninvasive ventilation (NIV) has been the first-line intervention for certain forms of acute respiratory failure. NIV may be delivered through the patient's mouth, nose, or both using noninvasive intermittent positive pressure ventilation or continuous positive airway pressure. When applied appropriately, NIV may reduce morbidity and mortality and may avert iatrogenic complications and infections associated with invasive mechanical ventilation. This article provides physicians and respiratory therapists with a comprehensive, practical guideline for using NIV in critical care. © 2015 Elsevier Inc.

Autophagy

2021

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…

EUROPEAN MANAGERIAL PROFESSION AND BEHAVIOR

2009

The European manager‘s behavior must be flexible and adaptable to the behaviors of various employees of the enterprise. Its flexibility enables the manager to act efficiently in the current, so mobile environment