Search results for " High-Risk"
showing 6 items of 16 documents
A new tool to process forecast meteorological data for atmospheric pollution dispersion simulations of accident scenarios: A Sicily-based case study
2021
Emergency response plans to mitigate the severity of the accidental release of hazardous compounds in the air have become a primary concern in view of the many adverse events occurred over the years in high-risk plants. To do this, an accurate estimate of forecast meteorological data to be used in dispersion models can be very useful to respond in advance to emergency situations. In this field, FORCALM is a new tool developed to elaborate European Centre for Medium-Range Weather Forecasts data on a 3D computational domain with a high-resolution grid. FORCALM data can be used to perform predictive simulations of impacts on local and regional levels by using CALPUFF modelling system. A case s…
Effects of Gestational Diabetes Mellitus on Cholesterol Metabolism in Women with High-Risk Pregnancies: Possible Implications for Neonatal Outcome
2022
Metabolic disorders in pregnancy, particularly gestational diabetes mellitus (GDM), are associated with an increased risk for adverse pregnancy outcome and long-term cardiometabolic health of mother and child. This study analyzed changes of serum cholesterol synthesis and absorption markers during the course of high-risk pregnancies, with respect to the development of GDM. Possible associations of maternal lipid biomarkers with neonatal characteristics were also investigated. The study included 63 women with high risk for development of pregnancy complications. Size and proportions of small low-density (LDL) and high-density lipoprotein (HDL) particles were assessed across trimesters (T1&nd…
Eight-point compass rose underlay technique in 72 consecutive elderly patients with large incisional hernia
2011
Summary Background Repair of incisional hernia (IH) in the elderly is a challenge for the surgeon. Primary closure is preferable but is not always possible because of high recurrence rates of IH repaired without a prosthesis and/or possible respiratory and cardiovascular complications due to extreme tension of the margins. We report our experience with underlay mesh placement in elderly patients with large IH. Methods A total of 72 patients from January 2003 to December 2009 underwent IH repair involving placement of an intraperitoneal Gore® DualMesh® prosthesis. The prosthesis was first anchored at eight points in a compass rose pattern using a Gore® suture passer and then firmly secured t…
Morphology of placental villi after premature delivery and its clinical relevance
1986
Based on a new concept of maturation of the placental villous tree and its disorders (synchronous and asynchronous immaturity, asynchronous maturity, hyperpermaturity, and terminal villi deficiency) we studied the possible effect of the placental villous tree on the premature onset of labour. In mature normal neonates irregular and asynchronous villous patterns were found in 50% of cases. In prematurely delivered neonates, only 33% of the corresponding placentas show synchronous immature villous patterns. Uterine bleeding in the first trimester was associated with a 42% of incidence of premature maturation of the villous tree. These findings strengthen the idea that hormonal imbalance in ea…
The Clinical Relevance of LDL Size and Subclasses Modulation in Patients with Type-2 Diabetes
2007
increasing evidence suggest that the "quality" rather than only the "quantity" of low density lipoproteins (LDL) exerts a great influence on the cardiovascular risk. Hypertriglyceridemia, low HDL-cholesterol and increased levels of small dense LDL characterise diabetic dyslipidemia. in subjects with type-2 diabetes LDL size seems also to represent a good marker of clinical apparent and non-apparent atherosclerosis. Recently, the Coordinating Committee of the National Cholesterol Education Program stated that high-risk patients may benefit of stronger therapeutical approaches, a category of subjects that include those with type-2 diabetes. Screening for the presence of small, dense LDL may p…
Lipīdu profila raksturojums un to atbilstība vadlīniju mērķiem koronārās sirds slimības pacientiem, kas stacionēti Latvijas Kardioloģijas centrā
2018
Ievads: Kardiovaskulārās slimības (KVS) mirstības ziņā joprojām ieņem pirmo vietu pasaulē. Latvijā 2014. gadā tās veidoja 64% no visiem nāves cēloņiem sievietēm un 49% no visiem nāves cēloņiem vīriešiem (OECD, 2017). Jo īpaši, zema blīvuma lipoproteīnu holesterīns (ZBLH) ir galvenais terapeitiskais mērķis, aizkavējot saslimšanu ar KVS. Nesen papildinātās dislipidēmijas ārstēšanas vadlīnijas nosaka ļoti augsta riska pacientiem ZBLH mērķa līmeni <1,8 mmol/L un sākotnējā ZBLH līmeņa pazemināšanu vismaz par 50%. Mērķis: Analizēt lipīdu mērķa līmeņu sasniegšanas biežumu – ZBLH <1,8 mmol/L un ne - ABLH <2,6 mmol/L, un analizēt lipīdus pazeminošo līdzekļu (LPL) lietošanu starp pacientiem ar ļoti a…