Search results for " INO"

showing 10 items of 1000 documents

Synthesis, structural characterization and antitumor activity of di- and tri-organotin(IV) complexes of D-galacturonic acid

2015

organotin(IV) complexes D-Galacturonic acid cytotoxic activitySettore CHIM/03 - Chimica Generale E InorganicaSettore BIO/10 - Biochimica
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Potential use of organotin(IV)-tripetide complexes as stopper in tumor cells growth.

2008

organotin(IV) tripeptide tumor cellsSettore CHIM/03 - Chimica Generale E Inorganica
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DNA binding and biological activity of Cu(II) and Zn(II) complexes of a 2,5-diphenyl[1,3,4]oxadiazole macrocycle ligand.

2011

oxadiazole DNA bindingSettore CHIM/03 - Chimica Generale E InorganicaSettore CHIM/08 - Chimica Farmaceutica
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THE ‘CRUCIFIED AND DEPOSED CHRIST’ OF MUSEO DIOCESANO OF PALERMO, ITALY. SCIENTIFIC STUDIES OF A SICILIAN PAPIER-MȂSCHÉ POLYCHROME SCULPTURE

2022

In this paper we describe scientific investigations on the artwork ‘Crucified and deposed Christ’ from the Diocesan Museum of Palermo. Multidisciplinary studies were carried out to obtain interesting information about constitutive materials and executive techniques of XVIII century Sicilian papier mâsché, as well as about the sculpture state of conservation and the recognition of the previous treatments.Examination of the polychrome sculpture was both non-invasive (IRR, IRC, UV fluorescence, EDXRF spectroscopy X-Radiography) and micro invasive (optical microscopy, scanning electron microscopy with energy dispersive X-ray spectroscopy SEM-EDX).SEM-EDX results showed the use of materials like…

papier-mâsché SEM-EDS HPLC polychrome sculpture microbial cultureSettore CHIM/03 - Chimica Generale E Inorganica
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Darbinieku radošās pašefektivitātes un individuālas inovatīvas uzvedības saistība

2017

The purpose of this research was to find out if there is a relationship between employees’ creative self-efficacy and innovative behavior. Nowadays great importance has granted to creative self-efficacy of employees and managers, which has been required to innovative development of company (Tierney & Farmer, 2010). Innovations and inner susceptibility are the main factors that define superiority of organization in conditions of competition (Lukes, 2013). Innovative behavior of staff, which has been descripted as development, adaptation and implementation in practice of new products, technologies and working methods, often are mentioned as valuable thing on the way to innovations and success…

pašefektivitātepieaugušieindividuāla inovatīva uzvedībaradošumsPsiholoģijaradošā pašefektivitāte
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Effects of soil inoculation with arbuscular mycorrhizal fungi on plant growth and nutrient uptake of some Mediterranean species grown under rainfed f…

2012

phosphorous uptakesoil inoculumarbuscular mycorrhizal fungiNitrogen uptakeSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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Synthesis, characterization, and cellular investigations of porphyrin– and chlorin–indomethacin conjugates for photodynamic therapy of cancer

2021

Indomethacin is a potent non-steroidal anti-inflammatory drug (NSAID) with a strong selective inhibitor activity towards cyclooxygenase-2 (COX-2), an enzyme that is highly overexpressed in various tumour cells, being involved in tumourigenesis. Concomitantly, porphyrins have gained much attention as promising photosensitizers (PSs) for the non-invasive photodynamic therapy (PDT) of cancer. Herein, we report the design, and determine the singlet oxygen generation capacity and in vitro cellular toxicity of porphyrin- and chlorin-indomethacin conjugates (P2-Ind and C2-Ind). Both the conjugates were obtained in high yields and were characterized by 1H, 19F and 13C NMR as well as by high resolut…

photosensitizermedicine.medical_treatmentPhotodynamic therapyDFT calculations010402 general chemistryPhotochemistry01 natural sciencesBiochemistrychemistry.chemical_compoundnon-steroidal anti-inflammatory drugpolycyclic compoundsmedicinePhysical and Theoretical ChemistryTriplet stateCytotoxicity010405 organic chemistrySinglet oxygenOrganic Chemistrysinglet oxygen generationPorphyrin0104 chemical sciencesPhotochemotherapychemistrySettore CHIM/03 - Chimica Generale E InorganicaChlorincytotoxicityPhototoxicityporphyrinConjugateOrganic & Biomolecular Chemistry
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Cyclo- and Polyphosphazenes for Biomedical Applications

2022

Cyclic and polyphosphazenes are extremely interesting and versatile substrates characterized by the presence of -P=N- repeating units. The chlorine atoms on the P atoms in the starting materials can be easily substituted with a variety of organic substituents, thus giving rise to a huge number of new materials for industrial applications. Their properties can be designed considering the number of repetitive units and the nature of the substituent groups, opening up to a number of peculiar properties, including the ability to give rise to supramolecular arrangements. We focused our attention on the extensive scientific literature concerning their biomedical applications: as antimicrobial age…

polyphosphazenesOrganic ChemistryPharmaceutical SciencepolyphosphazeneAnalytical Chemistrycyclophosphazenes; drug delivery; polyphosphazenes; tissue engineeringChemistry (miscellaneous)Settore CHIM/03 - Chimica Generale E Inorganicatissue engineeringDrug Discoverydrug deliverycyclophosphazenescyclophosphazeneMolecular MedicinePhysical and Theoretical Chemistry
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Poly[[tetramethanolbis[4-oxo-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-olato]disodium]–diethyl ether–metha…

2016

In the title compound, [Na2(C16H7Cl3N5O2)2(CH3OH)4]·C4H10O·2CH3OH, the central pyrazolo[3,4-d]pyrimidine system makes dihedral angles of 82.98 (7)° with the trichlorophenyl ring and 13.11 (15)° with the pyridine ring. The sodium ion has an octahedral environment, being coordinated by four methanol molecules and one O and one N atom of two different heterocyclic ring systems.

pyridinecrystal structure246-trichlorophenylPyrimidineStereochemistryCrystal structureDihedral angle010403 inorganic & nuclear chemistryRing (chemistry)01 natural sciencesMedicinal chemistrychemistry.chemical_compoundPyridinelcsh:QD901-999sodiumbiology010405 organic chemistrypyrazolo[34-d]pyrimidin-6-olateGeneral Medicinebiology.organism_classification0104 chemical scienceschemistryTetralcsh:CrystallographyMethanolDiethyl etherIUCrData
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(E)-1-(Pyridin-4-yl)propan-1-one O-tosyl oxime

2017

The title compound, C15H16N2O3S, was obtained by the reaction of (E)-1-(pyridin-4-yl)propan-1-one oxime andpara-toluenesulfonic acid. The pyridine ring makes a dihedral angle of 54.70 (10)° with the benzene ring. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming a chain along thec-axis direction.

pyridinecrystal structureHydrogen bondCrystal structureDihedral angle010402 general chemistry010403 inorganic & nuclear chemistryRing (chemistry)Oximehydrogen bonding01 natural sciences0104 chemical sciencesCrystalchemistry.chemical_compoundCrystallographytosyl oximechemistryTosylPyridinelcsh:QD901-999lcsh:CrystallographyIUCrData
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