Search results for " INTERPRETATION"
showing 10 items of 555 documents
Mitral valve annuloplasty and papillary muscle relocation oriented by 3-dimensional transesophageal echocardiography for severe functional mitral reg…
2012
Objective The study of the mitral valve apparatus and its modifications during functional mitral regurgitation (FMR) is better revealed by 3-dimensional (3D) transesophageal echocardiography (TOE). To plan mitral valve repair by annuloplasty and papillary muscle (PPM) relocation, we proposed a valve repair procedure oriented by the new main features obtained by real-time 3D TOE reconstruction of the mitral valve apparatus. Methods Since January 2008, 25 patients with severe FMR before mitral valve repair were examined. Mean coaptation depth and mean tenting area were 1.3 ± 0.2 cm and 3.2 ± 0.5 cm 2 , respectively. Intraoperative 2D and 3D TOE were performed, followed by a 3D offline reconst…
GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data
2021
AbstractBackgroundThe interpretation of results from transcriptome profiling experiments via RNA sequencing (RNA-seq) can be a complex task, where the essential information is distributed among different tabular and list formats - normalized expression values, results from differential expression analysis, and results from functional enrichment analyses. A number of tools and databases are widely used for the purpose of identification of relevant functional patterns, yet often their contextualization within the data and results at hand is not straightforward, especially if these analytic components are not combined together efficiently.ResultsWe developed the GeneTonic software package, whi…
Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs
2006
Existing Trichomonas vaginalis therapies are out of reach for most trichomoniasis people in developing countries and, where available, they are limited by their toxicity (mainly in pregnant women) and their cost. New antitrichomonal agents are needed to combat emerging metronidazole-resistant trichomoniasis and reduce the side effects associated with currently available drugs. Toward this end, atom-based bilinear indices, a new TOMOCOMD-CARDD molecular descriptor, and linear discriminant analysis (LDA) were used to discover novel, potent, and non-toxic lead trichomonacidal chemicals. Two discriminant functions were obtained with the use of non-stochastic and stochastic atom-type bilinear in…
Quark and gluon distributions and $\alpha_{s}$ from nucleon structure functions at low $x$
1993
Abstract The Q2 dependence of the structure functions F2p and F2d recently measured by the NMC is compared with the predictions of perturbative QCD at next-to-leading order. Good agreement is observed, leading to accurate determinations of the quark and gluon distributions in the range 0.008 ⩽ × ⩽ 0.5. The strong coupling constant is measured from the low x data; the result agrees with previous determinations.
Polimorfismos en el gen de la apolipoproteína E y riesgo de hipercolesterolemia: un estudio de casos y controles en una población laboral de Valencia
2000
Fundamento El gen de la apolipoproteina E (apoE) presenta tres variantes comunes (alelos ɛ2, ɛ3, ɛ4), cuya frecuencia alelica y asociacion con los lipidos plasmaticos varia segun las poblaciones. Nuestro objetivo fue estimar la asociacion entre estas variantes geneticas y el riesgo de hipercolesterolemia en la poblacion mediterranea espanola. Pacientes y metodo Se ha realizado un estudio de casos y controles en una poblacion laboral de Valencia. Se identificaron 330 casos (148 varones y 182 mujeres) con hipercolesterolemia moderada (colesterol total > 200 mg/dl o con tratamiento hipolipemiante) y un intervalo de edad entre 20–60 anos. Se seleccionaron 330 controles normocolesterolemicos apa…
Le réalisme social américain à l'ère postmoderne : (Russell Banks, Raymond Carver, Richard Ford)
2012
His study focuses on the works of Russell Banks, Raymond Carver and Richard Ford. They started writing during the 1960s and 1970s, at a time when the self-reflexivity and metafictional play of postmodernist writers were drawing a lot of critical attention in academic circles. However, they consider themselves to be realist writers. In “A Few Words about Minimalism,” John Barth suggested that the return to realist fiction in the mid-1970s could be both a reaction against so-called “postmodernist” fiction and a symptom of the social and economic unease of the period. Indeed, Cathedral, Continental Drift and The Sportswriter describe in accurate detail the everyday lives of ordinary American m…
Regularization operators for natural images based on nonlinear perception models.
2006
Image restoration requires some a priori knowledge of the solution. Some of the conventional regularization techniques are based on the estimation of the power spectrum density. Simple statistical models for spectral estimation just take into account second-order relations between the pixels of the image. However, natural images exhibit additional features, such as particular relationships between local Fourier or wavelet transform coefficients. Biological visual systems have evolved to capture these relations. We propose the use of this biological behavior to build regularization operators as an alternative to simple statistical models. The results suggest that if the penalty operator take…
Running to keep up with the lecturer or gradual de-ritualization? Biology students’ engagement with construction and data interpretation graphing rou…
2021
Abstract Through a commognitive lens, we examine twelve first-semester biology students’. engagement with graphing routines as they work in groups, during four sessions of Mathematical Modelling (MM). We trace the students’ meta-level learning, particularly as they fluctuate between deploying graphs for mere illustration of data and as sense-making tools. We account for student activity in relation to precedent events in their experiences of graphing and as fluid, if not always productive, interplay between ritualised and exploratory engagement with graph construction and interpretation routines. The students’ construal of the task situations is marked by efforts to keep up with lecturer ex…
[Current developments and perspectives on the diagnosis and treatment of urinary incontinence and genital prolapse in women].
2012
As a key area of gynaecology, urogynaecology has undergone impressive changes in the past few years. Together with the high prevalence of functional pelvic floor disorders, modern anaesthesia procedures and the introduction of new, innovative minimally invasive operation techniques have led to a dramatic increase in the number of operations for incontinence and prolapses. The increasingly subtle diagnostic options, such as, e. g., 2D and 3D sonography of the pelvic floor provide unambiguous findings and facilitate decision making. Tension-free vaginal slings in retro-pubic, trans-obturator or single-incision techniques show a high success rate with few complications and have almost complete…
Microaneurysm detection with radon transform-based classification on retina images.
2012
The creation of an automatic diabetic retinopathy screening system using retina cameras is currently receiving considerable interest in the medical imaging community. The detection of microaneurysms is a key element in this effort. In this work, we propose a new microaneurysms segmentation technique based on a novel application of the radon transform, which is able to identify these lesions without any previous knowledge of the retina morphological features and with minimal image preprocessing. The algorithm has been evaluated on the Retinopathy Online Challenge public dataset, and its performance compares with the best current techniques. The performance is particularly good at low false p…