Search results for " Immediate"

showing 10 items of 65 documents

Asthma exacerbations and socio-economic status in French adults with persistent asthma: A prospective cohort study.

2017

Adults disadvantaged by poor socio-economic status (SES) are more severely affected by asthma compared to those with better SES. We aimed to determine whether the frequency of asthma exacerbations (AEx), as well as aspects related to AEx management, differed based on SES in patients treated with daily treatments.This study, part of the prospective observational cohort ASTRO-LAB, included French adult patients with persistent asthma. Patients were considered as low SES if they benefited from publicly funded special health insurance and/or were perceived as low SES by their general practitioner. AEx was defined as at least one of the following: asthma-related oral corticosteroid course, medic…

Pulmonary and Respiratory MedicineAdultHypersensitivity ImmediateMalePediatricsmedicine.medical_specialtyAdolescentGeneral PracticeComorbiditySeverity of Illness IndexBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineImmunology and AllergyMedicineHumans030212 general & internal medicineSocial determinants of healthAnti-Asthmatic AgentsProspective StudiesProspective cohort studySocioeconomic statusAsthmaAsthma exacerbationsMedical Assistancebusiness.industrysocial sciencesmedicine.diseaseAsthma030228 respiratory systemSocioeconomic FactorsPediatrics Perinatology and Child HealthCohortpopulation characteristicsObservational studyFemaleFrancebusinessEmergency Service HospitalCohort studyThe Journal of asthma : official journal of the Association for the Care of Asthma
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How pediatricians in Spain manage the first acute wheezing episode in an atopic infant. Results from the TRAP study.

2005

Abstract Background Although the treatment of asthma has been addressed in several guidelines, the management of the first acute wheezing episode in infants has not often been evaluated. We surveyed practicing pediatricians in Spain about the treatment they would provide in a simulated case. Material and methods A random sample of 3000 pediatricians and physicians who normally treated children was surveyed. The questionnaire inquired about how they would treat a first mild-to-moderate wheezing attack in a 5-month-old boy with a personal and family history of allergy. Pediatricians were asked about their professional background. Results A total of 2347 questionnaires were returned with usefu…

Pulmonary and Respiratory MedicineHypersensitivity ImmediateAllergyPediatricsmedicine.medical_specialtyImmunologyAdrenergic beta-AntagonistsAdministration OralPrimary carePediatricsMaintenance therapyAdrenal Cortex HormonesAdrenergic beta-2 Receptor AntagonistsRecurrenceSurveys and QuestionnairesAdministration InhalationmedicineImmunology and AllergyHumansRespiratory soundsAnti-Asthmatic AgentsMetered Dose InhalersFamily historyPractice Patterns Physicians'AsthmaRespiratory Soundsmedicine.diagnostic_testBronchial Spasmbusiness.industryInhalerData CollectionMasksInfantGeneral Medicinemedicine.diseaseAsthmaSpainChild PreschoolOral steroidAcute DiseasePractice Guidelines as TopicDrug Therapy CombinationGuideline AdherencebusinessCase ManagementInhalation SpacersAllergologia et immunopathologia
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A potential link between serum low-density lipoproteins and asthma

2015

Pulmonary and Respiratory MedicineHypersensitivity ImmediateMaleApolipoprotein A-Ibusiness.industryCholesterol HDLSettore MED/10 - Malattie Dell'Apparato RespiratorioCritical Care and Intensive Care Medicinemedicine.diseaseAsthmaText miningForced Expiratory VolumeImmunologyLow densityMedicineFemaleApolipoprotein A-I; Asthma; Cholesterol HDL; Female; Humans; Hypersensitivity Immediate; Male; Forced Expiratory VolumebusinessLink (knot theory)AsthmaHuman
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Factors that influence exhaled nitric oxide in Italian schoolchildren

2008

Conflicting results exist about the meaning of exhaled nitric oxide (eNO) in epidemiologic studies, mainly because of the numerous factors that may affect the measurement.To evaluate the role of the factors that influence eNO levels in a sample of schoolchildren with or without respiratory diseases. We studied 335 schoolchildren, ages 10 to 16 years, from 8 schools in Palermo, Italy. After a respiratory questionnaire was completed, spirometry, skin tests, and eNO measurements were performed.Among 335 children, 13.7% reported symptoms of bronchial asthma, 46.9% reported symptoms of rhinitis, and 39.4% were asymptomatic. The ratio of forced expiratory volume in 1 second to forced vital capaci…

Pulmonary and Respiratory MedicineSpirometryHypersensitivity ImmediateMalemedicine.medical_specialtyPediatricsVital capacityBreath TestAdolescentImmunologySex FactorNitric OxideAsymptomaticAtopySex FactorsInternal medicineSex Factors; Skin Tests; Exhalation; Humans; Asthma; Rhinitis; Child; Italy; Nitric Oxide; Cross-Sectional Studies; Spirometry; Allergens; Hypersensitivity Immediate; Adolescent; Breath Tests; Female; MalemedicineImmunology and AllergyHumansRespiratory systemChildSensitizationRhinitiAsthmaRhinitisSkin TestsCross-Sectional Studiemedicine.diagnostic_testSkin Testbusiness.industryAllergenAllergensmedicine.diseaseAsthmamedicine.anatomical_structureCross-Sectional StudiesBreath TestsItalyExhalationSpirometryExhaled nitric oxideFemalemedicine.symptombusinessHuman
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The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments.

1995

The low molecular weight GTP-binding proteins RhoA, RhoB, and RhoC are characterized as specific substrates for the ADP-ribosyltransferase C3 from Clostridium botulinum and are supposed to be involved in the organization of the microfilamental network and transformation. rhoB is known to be immediate-early inducible by growth factors and protein-tyrosine kinases. Since increasing evidence indicates overlapping of growth factor- and UV-induced signal pathways, we studied the effect of UV light and other genotoxic agents on early rhoB transcription. Within 30 min after UV irradiation of NIH3T3 cells, the amount of rhoB mRNA increased 3-4-fold. Elevated rhoB mRNA was accompanied by an increase…

RHOAUltraviolet RaysRHOBRetinoic acidCycloheximideBiologyBiochemistrychemistry.chemical_compoundMiceGTP-Binding ProteinsRhoB GTP-Binding ProteinAnimalsRNA MessengerProtein kinase ArhoB GTP-Binding ProteinMolecular BiologyGenes Immediate-EarlyAdenosine Diphosphate RiboseKinaseMembrane ProteinsCell Biology3T3 CellsDNAMolecular biologychemistryGene Expression Regulationbiology.proteinDactinomycinTetradecanoylphorbol AcetateSignal transductionDNA DamageThe Journal of biological chemistry
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Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies.

2008

Over a decade of in-vitro data support a critical role for members of the Homer family of postsynaptic scaffolding proteins in regulating the functional architecture of glutamate synapses. Earlier studies of Homer knockout mice indicated a necessary role for Homer gene products in normal mesocorticolimbic glutamate transmission and behaviours associated therewith. The advent of adeno-associated viral vectors carrying cDNA for, or short hairpin RNA against, specific Homer isoforms enabled the site-directed targeting of Homers to neurons in the brain. This approach has allowed our groups to address developmental issues associated with conventional knockout mice, to confirm active roles for di…

Scaffold proteinSubstance-Related DisordersTransgeneEmotionsGenetic VectorsGlutamic AcidMice TransgenicBiologySynaptic TransmissionArticleViral vectorAdenoviridaeSmall hairpin RNAMiceNeurochemicalHomer Scaffolding ProteinsAnimalsGeneGenes Immediate-EarlyPharmacologyMice KnockoutBehavior AnimalGlutamate receptorGene Transfer TechniquesBrainPsychiatry and Mental healthAlcoholismKnockout mouseMutagenesis Site-DirectedArousalCarrier ProteinsNeuroscienceBehavioural pharmacology
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La riforma "Orlando" e la semplificazione del sistema delle impugnazioni: dalla "specificità" dei motivi alla struttura 'mutevole' dell'appello

2017

Dopo avere tracciato un quadro generale sulle novità in tema di impugnazioni introdotte dalla legge 23 giugno 2017, n. 103, l'A. si dedica, in particolare, a due modifiche che generano incertezze interpretative : il nuovo e più esteso parametro di specificità richiesto per l'atto di impugnazione, correlato all'inedito modello di sentenza cui dovrà adeguarsi il giudice nella redazione della motivazione, e il nuovo caso di rinnovazione obbligatoria dell'istruzione dibattimentale previsto dal comma 3 bis dell'art. 603 c.p.p. Ne deriva un giudizio di appello con struttura 'mutevole': novum iudicium quando l'itinerario dibattimentale è con istruzione, revisio prioris istantiae quando invece è se…

Settore IUS/16 - Diritto Processuale PenaleAppello - Impugnazioni penali - riforma - Motivi di impugnazione - Sentenza - Struttura della sentenza - Concordato sui motivi - Rinnovazione istruzione dibattimentale - Immediatezza - Oralità - Prova in appello
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Una ventata di «legalità probatoria» nel giudizio di seconda istanza

2013

Ancora una volta, la Suprema Corte, in conformità ai dicta della Corte e.d.u., pone l’accento sulla necessità dell’assunzione della prova orale in appello nella ipotesi in cui il giudice intenda apprezzarne diversamente l’attendibilità e, sulla base della nuova lettura, ribaltare l’esito assolutorio di primo grado. Nel caso di specie si rimprovera alla Corte d’appello di avere operato una valutazione negativa di attendibilità dei testimoni della difesa, rilevandone incoerenze e contrasti, senza, tuttavia, chiamare i medesimi testimoni a spiegare le imprecisioni riscontrate. Tale grave omissione ha, secondo la Cassazione, reso gli esami «incompleti e parziali e, come tali, non suscettibili d…

Settore IUS/16 - Diritto Processuale PenaleAppello - Rinnovazione dell'istruzione dibattimentale - Immediatezza - Dan c. Moldavia
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Ancora in tema di rinnovazione della prova orale in appello

2014

Torna ad essere affrontata dalla Suprema Corte la questione della necessità, per il giudice d’appello che intende riformare la sentenza di primo grado, di raccogliere nuovamente innanzi a sé la prova orale. I giudici di legittimità hanno annullato la sentenza emessa dalla Corte d’appello di Bari con la quale, in riforma della prima decisione di condanna, era stata affermata la non colpevolezza degli imputati sulla base di una diversa lettura delle dichiarazioni rese dalla persona offesa. Il giudice d’appello, in particolare, senza disporne la rinnovazione, le ha valutate intrinsecamente inattendibili, alla luce delle discrasie emerse tra quanto riferito in denuncia e quanto dichiarato al pu…

Settore IUS/16 - Diritto Processuale PenaleAppello penale - Rinnovazione dell'istruzione dibattimentale - Limiti - Immediatezza - Riforma in peius
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Commento all'art. 525 c.p.p.

2008

Il commento prende in rassegna sia l'immediatezza nella deliberazione della sentenza come esplicazione del principio di concentrazione, sia l'immediatezza sotto il profilo soggettivo della decisione, tradotto nel principio d'immutabilità fisica del decidente. L'analisi si sofferma soprattutto su questo aspetto, ritenendo, l'Autrice, come con tale disposizione il legislatore abbia dato formale riconoscimento al principio di oralità, che quindi, non è da intendere confinato nella sola legge delega n. 81 del 1987 (Direttiva n. 2).

Settore IUS/16 - Diritto Processuale PenaleImmutabilità del giudice - Immediatezza - Deliberazione della sentenza - Concentrazione
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