Search results for " Inference"
showing 10 items of 337 documents
What Does Objective Mean in a Dirichlet-multinomial Process?
2017
Summary The Dirichlet-multinomial process can be seen as the generalisation of the binomial model with beta prior distribution when the number of categories is larger than two. In such a scenario, setting informative prior distributions when the number of categories is great becomes difficult, so the need for an objective approach arises. However, what does objective mean in the Dirichlet-multinomial process? To deal with this question, we study the sensitivity of the posterior distribution to the choice of an objective Dirichlet prior from those presented in the available literature. We illustrate the impact of the selection of the prior distribution in several scenarios and discuss the mo…
A Bayesian Sequential Look at u-Control Charts
2005
We extend the usual implementation of u-control charts (uCCs) in two ways. First, we overcome the restrictive (and often inadequate) assumptions of the Poisson model; next, we eliminate the need for the questionable base period by using a sequential procedure. We use empirical Bayes(EB) and Bayes methods and compare them with the traditional frequentist implementation. EB methods are somewhat easy to implement, and they deal nicely with extra-Poisson variability (and, at the same time, informally check the adequacy of the Poisson assumption). However, they still need the base period. The sequential, full Bayes approach, on the other hand, also avoids this drawback of traditional u-charts. T…
Correcting for non-ignorable missingness in smoking trends
2015
Data missing not at random (MNAR) is a major challenge in survey sampling. We propose an approach based on registry data to deal with non-ignorable missingness in health examination surveys. The approach relies on follow-up data available from administrative registers several years after the survey. For illustration we use data on smoking prevalence in Finnish National FINRISK study conducted in 1972-1997. The data consist of measured survey information including missingness indicators, register-based background information and register-based time-to-disease survival data. The parameters of missingness mechanism are estimable with these data although the original survey data are MNAR. The u…
Conditionally heteroscedastic intensity-dependent marking of log Gaussian Cox processes
2009
Spatial marked point processes are models for systems of points which are randomly distributed in space and provided with measured quantities called marks. This study deals with marking, that is methods of constructing marked point processes from unmarked ones. The focus is density-dependent marking where the local point intensity affects the mark distribution. This study develops new markings for log Gaussian Cox processes. In these markings, both the mean and variance of the mark distribution depend on the local intensity. The mean, variance and mark correlation properties are presented for the new markings, and a Bayesian estimation procedure is suggested for statistical inference. The p…
A Bayesian analysis of classical hypothesis testing
1980
The procedure of maximizing the missing information is applied to derive reference posterior probabilities for null hypotheses. The results shed further light on Lindley’s paradox and suggest that a Bayesian interpretation of classical hypothesis testing is possible by providing a one-to-one approximate relationship between significance levels and posterior probabilities.
What Bayesians Expect of Each Other
1991
Abstract Our goal is to study general properties of one Bayesian's subjective beliefs about the behavior of another Bayesian's subjective beliefs. We consider two Bayesians, A and B, who have different subjective distributions for a parameter θ, and study Bayesian A's expectation of Bayesian B's posterior distribution for θ given some data Y. We show that when θ can take only two values, Bayesian A always expects Bayesian B's posterior distribution to lie between the prior distributions of A and B. Conditions are given under which a similar result holds for an arbitrary real-valued parameter θ. For a vector parameter θ we present useful expressions for the mean vector and covariance matrix …
An introduction to Bayesian reference analysis: inference on the ratio of multinomial parameters
1998
This paper offers an introduction to Bayesian reference analysis, often described as the more successful method to produce non-subjective, model-based, posterior distributions. The ideas are illustrated in detail with an interesting problem, the ratio of multinomial parameters, for which no model-based Bayesian analysis has been proposed. Signposts are provided to the huge related literature.
Pathway analysis of high-throughput biological data within a Bayesian network framework
2011
Abstract Motivation: Most current approaches to high-throughput biological data (HTBD) analysis either perform individual gene/protein analysis or, gene/protein set enrichment analysis for a list of biologically relevant molecules. Bayesian Networks (BNs) capture linear and non-linear interactions, handle stochastic events accounting for noise, and focus on local interactions, which can be related to causal inference. Here, we describe for the first time an algorithm that models biological pathways as BNs and identifies pathways that best explain given HTBD by scoring fitness of each network. Results: Proposed method takes into account the connectivity and relatedness between nodes of the p…
Extending graphical models for applications: on covariates, missingness and normality
2021
The authors of the paper “Bayesian Graphical Models for Modern Biological Applications” have put forward an important framework for making graphical models more useful in applied settings. In this discussion paper, we give a number of suggestions for making this framework even more suitable for practical scenarios. Firstly, we show that an alternative and simplified definition of covariate might make the framework more manageable in high-dimensional settings. Secondly, we point out that the inclusion of missing variables is important for practical data analysis. Finally, we comment on the effect that the Gaussianity assumption has in identifying the underlying conditional independence graph…
Statistical inference and Monte Carlo algorithms
1996
This review article looks at a small part of the picture of the interrelationship between statistical theory and computational algorithms, especially the Gibbs sampler and the Accept-Reject algorithm. We pay particular attention to how the methodologies affect and complement each other.