Search results for " Informatica"

Lightweight LCP construction for next-generation sequencing datasets

2012

The advent of "next-generation" DNA sequencing (NGS) technologies has meant that collections of hundreds of millions of DNA sequences are now commonplace in bioinformatics. Knowing the longest common prefix array (LCP) of such a collection would facilitate the rapid computation of maximal exact matches, shortest unique substrings and shortest absent words. CPU-efficient algorithms for computing the LCP of a string have been described in the literature, but require the presence in RAM of large data structures. This prevents such methods from being feasible for NGS datasets. In this paper we propose the first lightweight method that simultaneously computes, via sequential scans, the LCP and B…

A thread through challenging questions

2015

In the pages which follow I shall try to present a network relating some challenging different problems and questions; questions and problems which in different forms have been discussed with Enric along the years. The thread, of course, is constructed by me and now, and is based on my memory, choices and preferences. For these reasons I am not sure that Enric will totally agree with the particular way in which I have intertwined the different elements composing the thread as well as the pieces it connects. However I presume that this thread - also in the specific subjective form as it appears - will show, anyway, some elements of Enric’s activity and the way in which we have interacted alo…

The Hints from the Crowd Project

2013

Can the crowd be a source of information? Is it possible to receive useful hints from comments, blogs and product reviews? In the era of Web 2.0, people are allowed to give their opinion about everything such as movies, hotels, etc.. These reviews are social knowledge, that can be exploited to suggest possibly interesting items to other people. The goal of the Hints From the Crowd HFC project is to build a NoSQL database system for large collections of product reviews; the database is queried by expressing a natural language sentence; the result is a list of products ranked based on the relevance of reviews w.r.t. the natural language sentence. The best ranked products in the result list ca…

A Framework for Opening Data and Creating Advanced Services in the Health and Social Fields

2016

Open data is publicly available data that can be universally and readily accessed, used, and redistributed. Open data holds particular potential in the health and social sectors but, presently, health and social data are often published in a ‘closed’ format.There are different tools that allow to ‘open’ data, clean, structure and process them in order to elaborate them and build advanced services but, unfortunately, there is no single tool that can be used to perform all different tasks. We believe that the availability of Open Data in the health and social fields should be greatly increased and a way for creating new health and social services should be provided. In this paper, we present …

Algorithms for internal validation clustering measures in the post genomic era.

2011

Topological ranks reveal functional knowledge encoded in biological networks: a comparative analysis

2022

Abstract Motivation Biological networks topology yields important insights into biological function, occurrence of diseases and drug design. In the last few years, different types of topological measures have been introduced and applied to infer the biological relevance of network components/interactions, according to their position within the network structure. Although comparisons of such measures have been previously proposed, to what extent the topology per se may lead to the extraction of novel biological knowledge has never been critically examined nor formalized in the literature. Results We present a comparative analysis of nine outstanding topological measures, based on compact vie…

Aggregation and remuneration in Demand-Response with a blockchain-based framework

2020

This paper describes the possibility to use the blockchain technology for load and generation aggregation in a new distributed Demand Response (DR) service and customers remuneration system. The blockchain technology and the use of smart contracts for DR allow the creation of a distributed system in which customers can communicate directly, in a transparent, secure and traceable way, with the grid operator to provide their flexibility. In this paper, the DR problem formulation takes into account several aspects, which are periodically executed. First, the blockchain records customers’ energy consumption or production, then, the smart contract starts calculating the baseline and the potentia…

Comparison between two different cardiovascular models during a hemorrhagic shock scenario

2020

Hemorrhagic shock is a form of hypovolemic shock determined by rapid and large loss of intravascular blood volume and represents the first cause of death in the world, whether on the battlefield or in civilian traumatology. For this, the ability to prevent hemorrhagic shock remains one of the greatest challenges in the medical and engineering fields. The use of mathematical models of the cardiocirculatory system has improved the capacity, on one hand, to predict the risk of hemorrhagic shock and, on the other, to determine efficient treatment strategies. In this paper, a comparison between two mathematical models that simulate several hemorrhagic scenarios is presented. The models considere…

Assessment Of Driving Stress Through SVM And KNN Classifiers On Multi-Domain Physiological Data

2022

We propose an objective stress assessment method based on the extraction of features from physiological time series and their classification using Support Vector Machine and K-Nearest Neighbors algorithms. For this purpose, we used an open dataset consisting of multiparametric physiological signals (electrocardiogram, electromyogram, galvanic skin response and breath signal) obtained during the execution of a driving route within the city of Boston with restful, highway and city driving periods indicative of three different stress states. To predict the driver stress level, 21 features were extracted from 122 chunks of raw signals and were subsequently managed by classification algorithms. …

A portable system for multiple parameters monitoring: towards assessment of health conditions and stress level in the automotive field

2019

In this work, an electronic portable combo system able to synchronously acquire multiple signals, e.g. electrocardiographic (ECG), photoplethysmographic (PPG) and breathing waveforms, is presented. The realized system is also capable of showing in real time some physiological parameters which can be used for assessing health/stress status of the volunteer, such as heart rate and breathing frequency and their trends over time. Thanks to the use of non-invasive PPG probes, of batteries as power supply, and to the possibility to add in the future additional sensors to acquire other signals, the system could also be employed inside vehicles for assessing the status of the driver. Finally, the r…