6533b82efe1ef96bd12945ff

RESEARCH PRODUCT

Comparison between two different cardiovascular models during a hemorrhagic shock scenario

Jiraphat YokrattanasakLaura D'orsiValerio CusimanoLuciano CurcioAndrea De Gaetano

subject

blood flow simulationComputer science02 engineering and technologyShock HemorrhagichemodynamicsSettore ING-INF/01 - Elettronicahemorrhagic shockBattlefield0502 economics and business0202 electrical engineering electronic engineering information engineeringmedicineQA1-939HumansStructured modelSettore MAT/07 - Fisica MatematicaMathematical modelApplied Mathematics05 social sciencesModels CardiovascularGeneral MedicineComputational MathematicsRisk analysis (engineering)cardiovascular modelModeling and SimulationShock (circulatory)Settore ING-INF/06 - Bioingegneria Elettronica E InformaticaHemorrhagic shockTreatment strategy020201 artificial intelligence & image processingmedicine.symptomhemorrhageGeneral Agricultural and Biological Sciences050203 business & managementTP248.13-248.65MathematicsBiotechnology

description

Hemorrhagic shock is a form of hypovolemic shock determined by rapid and large loss of intravascular blood volume and represents the first cause of death in the world, whether on the battlefield or in civilian traumatology. For this, the ability to prevent hemorrhagic shock remains one of the greatest challenges in the medical and engineering fields. The use of mathematical models of the cardiocirculatory system has improved the capacity, on one hand, to predict the risk of hemorrhagic shock and, on the other, to determine efficient treatment strategies. In this paper, a comparison between two mathematical models that simulate several hemorrhagic scenarios is presented. The models considered are the Guyton and the Zenker model. In the vast panorama of existing cardiovascular mathematical models, we decided to compare these two models because they seem to be at the extremes as regards the complexity and the detail of information that they analyze. The Guyton model is a complex and highly structured model that represents a milestone in the study of the cardiovascular system; the Zenker model is a more recent one, developed in 2007, that is relatively simple and easy to implement. The comparison between the two models offers new prospects for the improvement of mathematical models of the cardiovascular system that may prove more effective in the study of hemorrhagic shock.

10.3934/mbe.2020272http://www.scopus.com/record/display.url?eid=2-s2.0-85090890954&origin=inward