Search results for " Ingegneri"
showing 10 items of 809 documents
An Open Innovation Decision Support System to Select a Biopharmaceutical R&D Portfolio
2016
Drugs available in the market today, selected several years ago under very uncertain future scenario, have experienced a long and expensive process of research and development carried out following both a closed and an open innovation path. To support this critical selection process, we propose a Decision Support System, able to choose among different candidates the most promising drugs along their best development path. The Decision Support System, based on a real options portfolio optimization model, mapping tools, and what-if rules as well, has been applied to a numerical example available in literature, and the research findings show interesting managerial and academic implications
A comprehensive analysis for N2O mechanisms by advanced mathematical techniques
2018
Recent evaluation of the existing activated sludge models, incorporating nitrous oxide (N2O) formation, is only based on the capabilities and inabilities in describing experimental data under different conditions. This paper will present an advanced mathematical modeling framework (i.e. coupling global sensitivity, identifiability and uncertainty analysis) for a comprehensive analysis on the evaluation of the structural differences among three ammonia oxidizing bacteria (AOB) two-pathway models in combination with two heterotrophic denitrification models. The analysis will be performed based on experimental data from a lab-scale deammonification granular sequencing batch reactor operated un…
Shaping inter-firm collaboration in new product development in the automobile industry: A trade-off between a transaction and relational-based approa…
2008
Abstract Shaping collaboration in the new product development (NPD) has always been a very difficult task, especially in complex industries like the automobile one. This complexity is particularly true during the engineering phase of the NPD process, where different complex systems are to be designed in a collaborative way. Basically, two-kind of approaches have been observed in the literature and industry: one is more related to market transactions, specifically the west car-company style, the other is more relational based, as in the Japanese car-company style. Now, the increasing globalisation of the industry asks for a merge of the two approaches; indeed, the increasing use of standard …
Development of a Decision Support System Framework for Cultural Heritage Management
2021
Decision support systems (DSSs) have been traditionally identified as useful information technology tools in a variety of fields, including the context of cultural heritage. However, to the best of our knowledge, no prior study has developed a DSS framework that incorporates all the main decision areas simultaneously in the context of cultural heritage. We fill this gap by focusing on design-science research and specifically by developing a DSS framework whose features support all the main decision areas for the sustainable management of cultural assets in a comprehensive manner. The main decision-making areas considered in our study encompass demand management, segmentation and communicati…
Nitrous oxide emission in a University of Cape Town membrane bioreactor: The effect of carbon to nitrogen ratio
2017
Abstract The effect of the carbon-to-nitrogen (C/N) ratio in the influent on the nitrous oxide (N 2 O) emission from a University of Cape Town Membrane BioReactor pilot plant was investigated. The membrane was located in a separate tank to single out the production of N 2 O due to the biological processes from N 2 O stripping as a result of the extra aeration needed for the mitigation of membrane fouling. The experimental campaign was divided into two phases, each characterized by a different C/N ratio (namely, 10 and 5 mgCOD/mgTN, Phase I and Phase II, respectively). The decrease of the C/N ratio promoted the increase of N 2 O emissions in both gaseous and dissolved phases, mainly due to a…
Shortcut nitrification-denitrification by means of autochthonous halophilic biomass in an SBR treating fish-canning wastewater
2017
Abstract Autochthonous halophilic biomass was cultivated in a sequencing batch reactor (SBR) aimed at analyzing the potential use of autochthonous halophilic activated sludge in treating saline industrial wastewater. Despite the high salt concentration (30 g NaCl L −1 ), biological oxygen demand (BOD) and total suspended solids (TSS), removal efficiencies were higher than 90%. More than 95% of the nitrogen was removed via a shortcut nitrification-denitrification process. Both the autotrophic and heterotrophic biomass samples exhibited high biological activity. The use of autochthonous halophilic biomass led to high-quality effluent and helped to manage the issues related to nitrogen removal…
Mathematical modelling of greenhouse gas emissions from membrane bioreactors: A comprehensive comparison of two mathematical models.
2018
Abstract This paper compares two mathematical models (Model I and Model II) to predict greenhouse gases emission from a University Cape Town (UCT) – membrane bioreactor (MBR) plant. Model I considers N 2 O production only during denitrification. Model II takes into account the ammonia-oxidizing bacteria (AOB) formation pathways for N 2 O. Both models were calibrated adopting real data. Model comparison was performed in terms of (i) sensitivity analysis (ii) best fit and (iii) model prediction uncertainty. On average 6% of factors of Model I and 9% of Model II resulted to be important. In terms of best fit, Model II had a better capability of reproducing the measured data. The average effici…
The effect of the solids and hydraulic retention time on moving bed membrane bioreactor performance
2018
Abstract The aim of the present paper was to investigate the effect of solids (SRT) and hydraulic (HRT) retention time on Integrated Fixed Film Activated Sludge (IFAS) University of Cape Town (UCT) membrane Bioreactor (MBR). In particular, three different pairs of SRT and HRT values were analysed, namely, Phase I 56 d/30 h, Phase II 31 d/15 h and Phase III 7 d/13 h. The short-term effect of these three SRT/HRT conditions was assessed by analysing several system performance indicators: organic carbon and biological nutrient (nitrogen and phosphorus) removal, biomass respiratory activity, activated sludge filtration properties and membrane fouling. The results showed that the decrease of SRT/…
Comparison of Two Mathematical Models for Greenhouse Gas Emission from Membrane Bioreactors
2017
In this study two mathematical models (Model I and Model II), able to predict the nitrous oxide (N2O) and carbon dioxide (CO2) emission from an University Cape Town (UCT) – membrane bioreactor (MBR) plant, have been compared. Model I considers the N2O production only during the denitrification. Model II takes into account the two ammonia-oxidizing bacteria (AOB) formation pathways for N2O. Both models were calibrated adopting real data. Results highlight that Model II had a better capability of reproducing the measured data especially in terms of N2O model outputs. Indeed, the average efficiency related to the N2O model outputs was equal to 0.3 and 0.38 for Model I and Model II respectively.
The sludge dewaterability in advanced wastewater treatment: a survey of four different Membrane BioReactor pilot plants
2017
The wasted activated sludge dewaterability represents a major concern for Wastewater Treatment Plants (WWTPs) managers. Indeed, whereas the dewatered sludge could represents a re-usable matrix, the principal drawback related to the wasted sludge dewaterability is the high water content due to the presence of extracellular polymeric substances (EPS) that allow the trapping of water molecules within the bio sludge flocs. In order to provide an outlook of the dewaterability features of activated sludge derived from advanced WWTP, the present research reports a long term survey (over two years) aimed at assessing the principal dewaterability parameters of the sludge wasted from different Membra…