Search results for " Interference"
showing 10 items of 340 documents
Comparing proton momentum distributions in A = 2 and 3 nuclei via 2H 3H and 3He (e,e′p) measurements
2019
We report the first measurement of the $(e,e'p)$ reaction cross-section ratios for Helium-3 ($^3$He), Tritium ($^3$H), and Deuterium ($d$). The measurement covered a missing momentum range of $40 \le p_{miss} \le 550$ MeV$/c$, at large momentum transfer ($\langle Q^2 \rangle \approx 1.9$ (GeV$/c$)$^2$) and $x_B>1$, which minimized contributions from non quasi-elastic (QE) reaction mechanisms. The data is compared with plane-wave impulse approximation (PWIA) calculations using realistic spectral functions and momentum distributions. The measured and PWIA-calculated cross-section ratios for $^3$He$/d$ and $^3$H$/d$ extend to just above the typical nucleon Fermi-momentum ($k_F \approx 250$ …
EMI Worsening in a SMPS with Non-linear Inductor
2022
This paper is focused on the input current in a Switched Mode Power Supply (SMPS) in which the power inductor is exploited up to the saturation showing a non-linear behaviour. The input current exhibits a distortion due to the non-linearity. The electromagnetic interference (EMI) caused by the ripple at switching frequency, superimposed to the DC value of the input current, requires a suitable design of the input differential mode (DM) filter. The input current is analyzed both in the time and frequency domain for different operating conditions, and it is compared to a SMPS equipped with a traditional linear inductor.
Application of 3D printed scavengers for improving the accuracy of single-particle inductively coupled plasma mass spectrometry analyses of silver na…
2023
The determination of silver nanoparticles (Ag NPs) with single-particle inductively coupled plasma mass spectrometry can be severely interfered with coexisting dissolved silver causing high background signals, which can lead to inaccurate quantification of NP size and particle concentration. In this paper, chemically active and reusable 3D printed scavengers are applied for highly efficient dissolved silver removal in Ag NP dispersions, allowing more accurate determination of particle concentration and size. Selective laser sintering was used for constructing the porous 3D scavengers constituting of polystyrene used as a supporting material and ion-exchange material SiliaBond Tosic acid (TA…
Characterizing a dc-SQUID and a Mo/TiW/Cu -trilayer transition-edge sensor array
2017
Tutkielmassa määritettiin uuden suprajohtavan kvantti-interferenssilaitteen ja 256 pikseliä sisältävän sirun transitioreunailmaisimien ominaisuuksia. Komponentit vaativat erittäin matalia lämpötiloja ja suojauksen suurilta magneettikentiltä muuttuakseen suprajohtaviksi. Tärkeimmät mitatut ominaisuudet olivat suprajohtavan kvantti-interferenssilaitteen signaalin vahvistuskerroin sekä kohina ja transitioreunailmaisimen transitiolämpötila, normaalitilan vastus, virta-jännite-käyttäytyminen, sekä kohina. Motivaationa tutkimukselle oli etsiä käytetyn mittalaite kokonaisuuden herkkyyden rajat sekä pyrkiä sovittamaan teoreettista mallia transitioreunailmaisimen kohinan ymmärtämiseksi. Korkean taaj…
Single-cell analysis of population context advances RNAi screening at multiple levels
2012
Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironment, in image‐based RNAi screens. We developed a comprehensive computational approach that employs Bayesian and multivariate methods at the single‐cell level. We applied these methods to 45 RNA interference screens of various sizes, including 7 druggable genome and 2 genome‐wide screens, analysing 17 different mammalian virus infections and four related cell physiological processes. Analysing cell‐based screens at this depth reveals widespread RNAi‐induce…
The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.
2021
Summary: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposable elements (TEs) are emerging as key contributors of aging and aging-related pathologies, including Alzheimer’s disease (AD) and cancer. However, the mechanisms governing heterochromatin maintenance or its relaxation in pathological conditions remain poorly understood. Here we show that PIN1, the only phosphorylation-specific cis/trans prolyl isomerase, whose loss is associated with premature aging and AD, is essential to preserve heterochromatin. We demonstrate that this PIN1 function is conserved from Drosophila to humans and prevents…
Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus
2010
Apoptosis is a fundamental host defence mechanism against invading microbes. Inactivation of NF-kappaB attenuates encephalomyocarditis virus (EMCV) virulence by triggering rapid apoptosis of infected cells, thereby pre-emptively limiting viral replication. Recent evidence has shown that hypoxia-inducible factor (HIF) increases NF-kappaB-mediated anti-apoptotic response in clear-cell renal cell carcinoma (CCRCC) that commonly exhibit hyperactivation of HIF due to the loss of its principal negative regulator, von Hippel-Lindau (VHL) tumour suppressor protein. Here, we show that EMCV challenge induces a strong NF-kappaB-dependent gene expression profile concomitant with a lack of interferon-me…
Leksiskā interference sinhronajā tulkošanā
2021
Sinhronajā tulkošanā par izplatītu kļūdu, kas mērķvalodu piesārņo ar nevēlamiem avotvalodas elementiem, tiek uzskatīta lingvistiskā interference. Pētījuma mērķis ir noteikt leksiskās interferences ietekmi uz vēstījuma precizitāti un skaidrību sinhronajos tulkojumos no angļu valodas uz latviešu valodu un no latviešu valodas uz angļu valodu. Izmantojot gan satura analīzi, gan sastatāmo analīzi, darbā tiek pētīts leksiskās interferences apjoms, veidi un ietekme. Rezultāti atklāj, ka leksiskā interference ir biežāk novērojama un daudzveidīgāka mutiskajos tulkojumos uz dzimto valodu, savukārt tulkojumos uz svešvalodu tā ievērojami vairāk maina oriģinālo vēstījumu. Jāsecina, ka sinhronajos tulkoj…
Differential effects of workaholism and work engagement on the interference between life and work domains
2018
This study analyzed the differences between workaholism and work engagement in relation to their influence on work–life interference. Workaholism is an addiction to work, characterized by obsessive attitude towards job, whereas work engagement concerns a positive pattern of thoughts and feelings about one’s job; these two constructs thus represent pathological and healthy forms of heavy work investment, respectively. As a consequence, it was expected that workaholism and work engagement would have different effects on perceived interference between work and life domains. We assessed levels of workaholism, work engagement, work-to-life interference, and life-to-work interference in a sample …
Čukstošas galerijas modas rezonatoru temperatūras sensors
2019
Čukstošo galerijas modu (ČGM) rezonatori ir sfēriskas formas objekti, kas ir taisīti no optiski caurspīdīgiem materiāliem un ir spējīgi uzturēt optiski cirkulējošu vilni iekšā sfērā, izmantojot pilnīgu iekšējo atstarošanos. Ja ir monohromātisks gaismas avots ar konstantu intensitāti, tad vilnis, kas kustās pa lodes perimetru, sāk konstruktīvi interferēt. Šajā gadījumā rodas rezonanse, ko sauc par čukstošo galeriju modu (ČGM), pēc analoģijas no akustikas. Darbā tiek aplūkots koncepts, ka ČGM rezonatorus varētu izmantot kā temperatūras sensorus. Izmantojot dažāda lieluma rezonatorus un mainot tempratūru, tiek testēta sistēma un rezonanses. Darbā tiek veidota praktiska sistēma ar kuras palīdzī…