Search results for " Laboratory"
showing 10 items of 622 documents
Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens
2019
25 Páginas, 7 figuras, 2 tablas
Investigation of superspreading COVID-19 outbreak events in meat and poultry processing plants in Germany: A cross-sectional study.
2020
Since May 2020, several COVID-19 outbreaks have occurred in the German meat industry despite various protective measures, and temperature and ventilation conditions were considered as possible high-risk factors. This cross-sectional study examined meat and poultry plants to examine possible risk factors. Companies completed a self-administered questionnaire on the work environment and protective measures taken to prevent SARS-CoV-2 infection. Multivariable logistic regression analysis adjusted for the possibility to distance at least 1.5 meters, break rules, and employment status was performed to identify risk factors associated with COVID-19 cases. Twenty-two meat and poultry plants with 1…
Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage
2021
The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is required for most of these interactions. For example, HIV-1 Nef activates the tyrosine kinase Hck by tightly binding to its SH3 domain. An archetypal contact between a negatively charged SH3 residue and a highly conserved arginine in Nef (Arg77) plays a key role here. Combining structural analyses with functional assays, we here show that Nef proteins have also developed a distinct structural strategy—termed the "R-clamp”—that favors the formation …
Radon and material radiopurity assessment for the NEXT double beta decay experiment
2015
Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM
The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells
2015
The modification of proteins by ubiquitin has a major role in cells of the immune system and is counteracted by various deubiquitinating enzymes (DUBs) with poorly defined functions. Here we identified the ubiquitin-specific protease USP8 as a regulatory component of the T cell antigen receptor (TCR) signalosome that interacted with the adaptor Gads and the regulatory molecule 14-3-3β. Caspase-dependent processing of USP8 occurred after stimulation of the TCR. T cell-specific deletion of USP8 in mice revealed that USP8 was essential for thymocyte maturation and upregulation of the gene encoding the cytokine receptor IL-7Rα mediated by the transcription factor Foxo1. Mice with T cell-specifi…
From Laboratory Mixes to Full Scale Test: Rutting Evaluation of Bio-recycled Asphalt Mixes
2021
The present paper describes the rutting behavior of innovative mixes incorporating 50% of Reclaimed Asphalt (RA) with bio-materials. They were assessed in the laboratory and in a full-scale accelerated experiment. The innovative mixes studied here contained bio-materials especially designed to help recycling by re-activating the aged binder from RA. Four mixes were evaluated: three of them are manufactured with bio-materials, (two bio-rejuvenators and one bio-binder) and one was a control mix, which was a high modulus asphalt mix (EME2). In this study, the rutting resistance of the four mixes was first evaluated in the laboratory with both European and US methods. The full-scale test was th…
Recovery Estimation of Dried Foodborne Pathogens Is Directly Related to Rehydration Kinetics.
2016
International audience; Drying is a common process which is used to preserve food products and technological microorganisms, but which is deleterious for the cells. The aim of this study is to differentiate the effects of drying alone from the effects of the successive and necessary rehydration. Rehydration of dried bacteria is a critical step already studied in starter culture but not for different kinetics and not for pathogens. In the present study, the influence of rehydration kinetics was investigated for three foodborne pathogens involved in neonatal diseases caused by the consumption of rehydrated milk powder: Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enteri…
An interlaboratory study as useful tool for proficiency testing of chemical oxygen demand measurements using solid substrates and liquid samples with…
2009
In 2008, the first Proficiency Testing Scheme of Chemical Oxygen Demand (1stCOD-PTADG) was conducted to assess the results obtained for different research groups whose field work is mainly anaerobic digestion. This study was performed using four samples, two solid samples as raw materials and two solid samples to prepare high concentration suspended solid solutions. Invitations were sent to a large number of laboratories, mainly to anaerobic digestion research groups. Finally, thirty labs from sixteen countries agreed to participate, but for different reasons four participants could not send any data. In total, twenty-six results were reported to the COD-PT coordinator. This study showed th…
Implementasi Pembelajaran Fisika Berbasis Laboratorium Virtual terhadap Keterampilan Proses Sains dan Persepsi Mahasiswa
2018
Penelitian ini bertujuan untuk mengetahui penerapan pembelajaran fisika berbasis media laboratorium virtual , Keterampilan Proses Sains (KPS), dan persepsi mahasiswa pada mata kuliah fisika dasar. Metode penelitian menggunakan pre-eksperimental design dan teknik purposive sample digunakan untuk memilih sampel yaitu kelas pendidikan fisika dan pendidikan matematika Universitas Papua. Instrumen dalam penelitian ini yaitu lembar observasi dan penilaian KPS serta angket persepsi mahasiswa yang dinilai di akhir pembelajaran. Hasil penelitian menunjukkan persentase KPS yang diobservasi selama perkuliahan 86,4% ± SD 12,7 meliputi aspek keterampilan menggunakan alat, mengambil data, dan mengkomunik…
Determination of organic pollutants in Anguilla anguilla by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)
2021
© 2021 The Authors.