Search results for " Large"

showing 10 items of 392 documents

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines

2014

Cancer cell lines are a tremendous resource for cancer biology and therapy development. These multipurpose tools are commonly used to examine the genetic origin of cancers, to identify potential novel tumor targets, such as tumor antigens for vaccine devel-opment, and utilized to screen potential therapies in preclinical studies. Mutations, gene expression, and drug sensitivity have been determined for many cell lines using next-generation sequencing (NGS). However, the human leukocyte antigen (HLA) type and HLA expression of tumor cell lines, characterizations necessary for the development of cancer vaccines, have remained largely incomplete and, such information, when available, has been …

HLA typeCCLE Cancer Cell Line Encyclopediamedicine.medical_treatmentCOSMIC Catalog of Somatic Mutations in CancerImmunologyBRENDA BRaunschweig ENzyme DatabaseSNV single nucleotide variationRNA-SeqHuman leukocyte antigenBiologynsSNV non synonymous SNVTranscriptomeLoss of heterozygosityAntigenGenotypemedicineImmunology and AllergyRNA-SeqRNA-Seq RNA SequencingOriginal ResearchGeneticsHLA expressionneoepitopescancer cell linesSRA Sequence Read ArchiveCancerImmunotherapymedicine.diseaseHLA Human Leukocyte AntigenOncologyRPKM reads per kilobase of exon model per million mapped readsIEDB Immune Epitope Databasesomatic mutationsimmunotherapyDLBCL diffuse large B-cell lymphomaNGS Next Generation SequencingOncoImmunology
researchProduct

Measurement of $\Delta^{++}$(1232) production in hadronic Z decays

1995

A measurement of the \Delta^{++}(1232) inclusive production in hadronic decays of the Z at LEP is presented, based on 1.3 million hadronic events collected~ by the DELPHI~ detector in the 1994 LEP running~ period. The DELPHI ring imaging Cherenkov counters are used for identifying hadrons. The average \Delta^{++}(1232) multiplicity per hadronic event is 0.079 \pm 0.015 which is more than a factor of two below the JETSET, HERWIG and UCLA model predictions. It agrees with a recently proposed universal mass dependence of particle production rates in e^{+}e^- annihilations.

Hadronic decayNuclear and High Energy PhysicsParticle physicsE+E ANNIHILATIONSe+e- annihilationCherenkov detectorElectron–positron annihilationDELPHI; hadronic decay; Cherenkov detector; e+e- annihilationHadron01 natural sciencesPartícules (Física nuclear)law.inventionNuclear physicslaw0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Multiplicity (chemistry)010306 general physicsCherenkov radiationhadronic decayDELPHIPhysics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyLARGE ELECTRON POSITRON COLLIDERPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; DELPHIPARTICLE PHYSICSFísica nuclearHigh Energy Physics::ExperimentParticle Physics - ExperimentCherenkov detector
researchProduct

Clinical strategies for the management of intestinal obstruction and pseudo-obstruction. A Delphi Consensus study of SICUT (Società Italiana di Chiru…

2016

Intestinal obstructions/pseudo-obstruction of the small/large bowel are frequent conditions but their management could be challenging. Moreover, a general agreement in this field is currently lacking, thus SICUT Society designed a consensus study aimed to define their optimal workout.The Delphi methodology was used to reach consensus among 47 Italian surgical experts in two study rounds. Consensus was defined as an agreement of 75.0% or greater. Four main topic areas included nosology, diagnosis, management and treatment.A bowel obstruction was defined as an obstacle to the progression of intestinal contents and fluids generally beginning with a sudden onset. The panel identified four major…

HerniaDelphi TechniqueContrast MediaAcidosis; Conservative Treatment; Contrast Media; Delphi Technique; Diatrizoate Meglumine; Disease Management; Emergencies; Emergency Medicine; General Surgery; Hernia; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Intubation Gastrointestinal; Laparotomy; Societies Medical; Stents; Symptom Assessment; Tomography X-Ray ComputedConservative TreatmentStentHumansLarge bowel obstructionIntubation GastrointestinalSocieties MedicalDiatrizoate MeglumineEmergencieLaparotomyIntestinal Pseudo-ObstructionDisease ManagementSmall bowelDelphi study Intestinal obstruction Large bowel obstruction Pseudo-obstruction Small bowelDelphi studyAcidosiGeneral SurgeryEmergency MedicineStentsEmergenciesSymptom AssessmentAcidosisTomography X-Ray ComputedPseudo-obstructionIntestinal ObstructionHuman
researchProduct

Brane cosmology with an anisotropic bulk

2004

In the context of brane cosmology, a scenario where our universe is a 3+1-dimensional surface (the ``brane'') embedded in a five-dimensional spacetime (the ``bulk''), we study geometries for which the brane is anisotropic - more specifically Bianchi I - though still homogeneous. We first obtain explicit vacuum bulk solutions with anisotropic three-dimensional spatial slices. The bulk is assumed to be empty but endowed with a negative cosmological constant. We then embed Z_2-symmetric branes in the anisotropic spacetimes and discuss the constraints on the brane energy-momentum tensor due to the five-dimensional anisotropic geometry. We show that if the bulk is static, an anisotropic brane ca…

High Energy Physics - TheoryNuclear and High Energy Physicsmedia_common.quotation_subjectFOS: Physical sciencesContext (language use)Perfect fluidGeneral Relativity and Quantum Cosmology (gr-qc)Cosmological constantAstrophysics01 natural sciencesGeneral Relativity and Quantum CosmologyTheoretical physicsGeneral Relativity and Quantum Cosmology0103 physical sciencesBrane cosmologyTensor010306 general physicsmedia_commonPhysicsSpacetimeExtra Large Dimensions010308 nuclear & particles physics[PHYS.HTHE]Physics [physics]/High Energy Physics - Theory [hep-th]Astrophysics (astro-ph)Cosmology of Theories beyond the SMUniverseHigh Energy Physics - Theory (hep-th)Brane
researchProduct

Measurement of Event Shape and Inclusive Distributions at $\sqrt{s} =$ 130 and 136 GeV

1997

Inclusive charged particle and event shape distributions are measured using 321 hadronic events collected with the DELPHI experiment at LEP at effective centre of mass energies of 130 to 136 GeV. These distributions are presented and compared to data at lower energies, in particular to the precise Z data. Fragmentation models describe the observed changes of the distributions well. The energy dependence of the means of the event shape variables can also be described using second order QCD plus power terms. A method independent of fragmentation model corrections is used to determine $\alpha_s$ from the energy dependence of the mean thrust and heavy jet mass. It is measured to be: % %\alpha_s…

High energyParticle physicsZ(0) RESONANCEPhysics and Astronomy (miscellaneous)Electron–positron annihilationHADRONIC Z-DECAYS; E+E-ANNIHILATION; ALPHA-S; POWER CORRECTIONS; Z(0) RESONANCE; MONTE-CARLO; QCD MODELS; ENERGY; FRAGMENTATION; PREDICTIONSHadronPREDICTIONSThrust01 natural sciences7. Clean energyPartícules (Física nuclear)Nuclear physicsENERGYFragmentation (mass spectrometry)POWER CORRECTIONSMONTE-CARLO0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]ALPHA-S010306 general physicsDetectors de radiacióDELPHIPhysicsQuantum chromodynamics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyE+E-ANNIHILATIONLARGE ELECTRON POSITRON COLLIDERCharged particleHADRONIC Z-DECAYSLarge Electron–Positron ColliderPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; DELPHIQCD MODELSPARTICLE PHYSICSHigh Energy Physics::ExperimentFRAGMENTATIONParticle Physics - Experiment
researchProduct

The ATLAS Data Acquisition and High Level Trigger system

2016

Journal of Instrumentation 11(06), P06008 (2016). doi:10.1088/1748-0221/11/06/P06008

High level triggerComputer sciencedata acquisitionPhysics::Instrumentation and DetectorsLarge hadron collideronline filteringTrigger Concepts and Systems (Hardware and Software)Control and Monitor Systems Online01 natural sciencesOnline farms and online filteringData acquisitionRecopilación de datos[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Detectors and Experimental TechniquesInstrumentationMathematical PhysicsSettore FIS/01Online Farms and Online FilteringLarge Hadron ColliderControl and monitor systems onlineATLAS experimentATLASmedicine.anatomical_structureTrigger concepts and systems (hardware and software)Triggers and rulesComputer hardwareperformanceOnline farms andControl and monitor systems online; Data acquisition concepts; Online farms and online filtering; Trigger concepts and systems (hardware and software)Ciências Naturais::Ciências Físicas:Ciências Físicas [Ciências Naturais]Data Acquisition ConceptsATLAS detector; ATLAS experiment; CERN; Large Hadron ColliderATLAS experiment610Accelerator Physics and Instrumentation530LHC ATLAS High Energy Physics TriggerAtlas (anatomy)0103 physical sciencesmedicineddc:610ElectronicsInstrumentation (computer programming)Control and monitor systems online; Data acquisition concepts; Online farms and; online filtering; Trigger concepts and systems (hardware and software)010306 general physicsCiencias ExactasScience & Technology010308 nuclear & particles physicsbusiness.industryData acquisition conceptsFísicaAcceleratorfysik och instrumenteringtriggerSistema en líneaData flow diagrammonitoringHigh Energy Physics::Experimentbusiness
researchProduct

Large eddy simulations on the effect of the irregular roughness shape on turbulent channel flows

2019

Abstract Large Eddy Simulations (LES) are carried out to investigate on the mean flow in turbulent channel flows over irregular rough surfaces. Here the attention is focused to selectively investigate on the effect induced by crests or cavities of the roughness. The irregular shape is generated through the super-imposition of sinusoidal functions having random amplitude and four different wave-lengths. The irregular roughness profile is reproduced along the spanwise direction in order to obtain a 2D rough shape. The analysis of the mean velocity profiles shows that roughness crests induce higher effect in the outer-region whereas roughness cavities cause the highest effects in the inner-reg…

Higher order statisticMaterials scienceTurbulence simulationTurbulent channel flows Large eddy simulation02 engineering and technologyReynolds stressSurface finish01 natural sciencesReynolds numberSettore ICAR/01 - Idraulica010305 fluids & plasmasPhysics::Fluid Dynamicssymbols.namesake0203 mechanical engineering0103 physical sciencesMean flowReynolds equationAnisotropyChannel flowFluid Flow and Transfer ProcessesTurbulenceMean velocity profileMechanical EngineeringIrregular roughneReynolds numberSinusoidal functionMechanicsCondensed Matter PhysicsOpen-channel flowShear stre020303 mechanical engineering & transportsAmplitudeReynolds streTurbulence Irregular shapeTurbulence intensityLESsymbolsTurbulence modulationInternational Journal of Heat and Fluid Flow
researchProduct

Differential staining of mucin granules from epoxy resin sections by a phosphotungstic acid-methyl green procedure.

1991

After treatment of epoxy resin semithin sections from glutaraldehyde fixed rat large intestine with 5% aqueous phosphotungstic acid (PTA), staining with unpurified 0.2% solutions of methyl green at 60 C for 5 min produces a color differentiation between mucin granules of goblet cells. Some mucin granules and the glycocalyx appear deep green while the remaining granules, luminal mucin and collagen fibers are pink. The known contamination of unpurified methyl green with crystal violet seems to be responsible for the pink staining reaction of the latter structures, which also present an orange-red fluorescence under green exciting light. Electron microscopic observations show selective contras…

HistologyCytoplasmic Granuleslaw.inventionGlycocalyxchemistry.chemical_compoundMethyl GreenlawAnimalsPhosphotungstic acidCrystal violetIntestine LargeStaining and LabelingDifferential stainingEpoxy ResinsGastric MucinsMucinRats Inbred StrainsGeneral MedicinePhosphotungstic AcidStainingRatsMedical Laboratory TechnologyMicroscopy ElectronchemistryBiochemistryGentian VioletGlutaraldehydeElectron microscopeNuclear chemistryBiotechnichistochemistry : official publication of the Biological Stain Commission
researchProduct

HSP60 IS THE MOST PREDICTIVE HEAT SHOCK PROTEIN DURING LARGE BOWEL CARCINOGENESIS

2014

Hsp 60 Large Bowel Exosomes.
researchProduct

Rapidity correlations in Lambda baryon and proton production in hadronic Z0 decays

1998

In an analysis of multihadronic events recorded at LEP by DELPHI in the years 1992 through 1994, charged hadrons are identified using the measurement of their energy loss and their Cherenkov angle. Rapidity correlations of \La-\La, proton-proton, and \La-proton pairs are compared. The agreement with the string and cluster fragmentation models is tested. For those pairs that frame a meson in terms of rapidity the compensation of strangeness is studied. For \La{}$\overline{\mathrm{p}}$ pairs the additional correlation with respect to charged kaons is analysed.

IMAGING CHERENKOV DETECTOR; DELPHIParticle physicsNuclear and High Energy PhysicsMesonElectron–positron annihilationHadronNuclear TheoryStrangenessLambdaLambda baryon01 natural sciencesPartícules (Física nuclear)Nuclear physics0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Rapidity010306 general physicsNuclear ExperimentDELPHIPhysics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyLARGE ELECTRON POSITRON COLLIDERIMAGING CHERENKOV DETECTORLarge Electron–Positron ColliderPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; DELPHIPARTICLE PHYSICSPhysics::Accelerator PhysicsHigh Energy Physics::ExperimentParticle Physics - Experiment
researchProduct