Search results for " Levels"
showing 10 items of 483 documents
Clozapine plasma level monitoring for prediction of rehospitalization schizophrenic outpatients.
2011
INTRODUCTION: The aim of this naturalistic exploratory study was to examine whether blood antipsychotic drug concentrations can predict rehospitalizations in chronically medicated patients. METHODS: The study included schizophrenic outpatients under clozapine (CLZ) maintenance treatment, supervised by therapeutic drug monitoring (TDM). Patients were observed for a period of 21 months. Their on average monthly measured plasma levels and the date of rehospitalizations were recorded. The variability of the first 3 CLZ plasma levels, measured in 3.6 months, was compared between patients with and without rehospitalization. RESULTS: 23 patients participated of which 6 patients were rehospitalized…
Impact of Midregional N‐Terminal Pro–Atrial Natriuretic Peptide and Soluble Suppression of Tumorigenicity 2 Levels on Heart Rhythm in Patients Treate…
2021
Background We assessed the impact of preprocedural plasma levels of MRproANP (midregional N‐terminal pro–atrial natriuretic peptide) and sST2 (soluble suppression of tumorigenicity 2) on recurrence of atrial fibrillation (AF) at 1 year after catheter ablation of AF. Methods and Results This was a prospective, multicenter, observational study including patients undergoing catheter ablation of AF. MRproANP and sST2 were measured in a peripheral venous blood preprocedure, and MRproANP was assessed in the right and left atrial blood during ablation. The primary end point was recurrent AF between 3 and 12 months postablation, defined as a documented (>30 seconds) episode of AF, flutter, or a…
Does plasma endothelin during thrombolysis depend on infarct size? A pilot study
1995
Dear Sir, Endothelin is a recently discovered endotheliumderived vasoconstrictive peptide [1]. Endothelin's actions are altered in various models of cardiac injury [2]. Furthermore, it has been shown that endothelin is increased during reperfusion [2]. Studies have shown a significant increase in endothelin-1 (ET-1) in the early phases of acute myocardial infarction (AMI) and percutaneous transluminal coronary angioplasty (PTCA) [3-8]. In addition, a significant inverse relation between ventricular function and plasma ET-1 has been shown [6]. These data suggest that ET-1 may provide a marker of endothelial injury in the early phases of coronary ischemia or may even contribute to alterations…
Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site
2009
BACKGROUND: The aim of our study was to evaluate in patients with acute ischemic stroke the relationship between immuno-inflammatory variables, clinical outcome and infarct site. MATERIALS AND METHODS: We evaluated plasma levels of IL-1beta, TNF-alpha, IL-6 and IL-10, E-selectin, P-selectin, sICAM-1 ,sVCAM-1 vWF, TPA and PAI-1. RESULTS: Patients with cardioembolic subtype showed significantly higher median plasma levels of TNF-alpha, IL-6, IL-1beta whereas the lacunar subtype showed significantly lower median plasma levels of TNF-alpha, IL-6 and IL-1beta. CONCLUSIONS: A significant association was noted between the severity of neurological deficit at admission, the diagnostic subtype and so…
Complementary Judgment Matrix Method with Imprecise Information for Multicriteria Decision-Making
2018
The complementary judgment matrix (CJM) method is an MCDA (multicriteria decision aiding) method based on pairwise comparisons. As in AHP, the decision-maker (DM) can specify his/her preferences using pairwise comparisons, both between different criteria and between different alternatives with respect to each criterion. The DM specifies his/her preferences by allocating two nonnegative comparison values so that their sum is 1. We measure and pinpoint possible inconsistency by inconsistency errors. We also compare the consistency of CJM and AHP trough simulation. Because preference judgments are always more or less imprecise or uncertain, we introduce a way to represent the uncertainty throu…
Boundary regularity for degenerate and singular parabolic equations
2013
We characterise regular boundary points of the parabolic $p$-Laplacian in terms of a family of barriers, both when $p>2$ and $1<p<2$. Due to the fact that $p\not=2$, it turns out that one can multiply the $p$-Laplace operator by a positive constant, without affecting the regularity of a boundary point. By constructing suitable families of barriers, we give some simple geometric conditions that ensure the regularity of boundary points.
Gradient regularity for elliptic equations in the Heisenberg group
2009
Abstract We give dimension-free regularity conditions for a class of possibly degenerate sub-elliptic equations in the Heisenberg group exhibiting super-quadratic growth in the horizontal gradient; this solves an issue raised in [J.J. Manfredi, G. Mingione, Regularity results for quasilinear elliptic equations in the Heisenberg group, Math. Ann. 339 (2007) 485–544], where only dimension dependent bounds for the growth exponent are given. We also obtain explicit a priori local regularity estimates, and cover the case of the horizontal p-Laplacean operator, extending some regularity proven in [A. Domokos, J.J. Manfredi, C 1 , α -regularity for p-harmonic functions in the Heisenberg group for …
Discontinuous solutions of linear, degenerate elliptic equations
2008
Abstract We give examples of discontinuous solutions of linear, degenerate elliptic equations with divergence structure. These solve positively conjectures of De Giorgi.
Control of essential supremum of solutions of quasilinear degenerate parabolic equations
2001
Sufficient conditions are obtained so that a weak subsolution of a class of quasilinear degenerate parabolic equations, bounded from above on theparabolic boundary of the cylinder Q, turns out to be bounded from above in Q.
Probing Surface Quantum Flows in Deformed Pygmy Dipole Modes
2017
In order to explore the nature of collective modes in weakly bound nuclei, we have investigated deformation effects and surface flow patterns of isovector dipole modes in a shape-coexisting nucleus $^{40}$Mg. The calculations were done in a fully self-consistent continuum finite-amplitude Quasiparticle Random Phase Approximation (QRPA) in a large deformed spatial mesh. An unexpected result of pygmy and giant dipole modes having disproportionate deformation splittings in strength functions was obtained. Furthermore, the transition current densities demonstrate that the long-sought core-halo oscillation in pygmy resonances is collective and compressional, corresponding to the lowest excitatio…