Search results for " Library"
showing 10 items of 734 documents
A positional scanning combinatorial library of peptoids as a source of biological active molecules: identification of antimicrobials
2003
9 pages, 4 figures, 2 schemes, 3 tables.-- PMID: 12959560 [PubMed].-- Printed version published in issue Sep-Oct 2003.-- Supporting information available at: http://pubs.acs.org/doi/suppl/10.1021/cc020075u
Graduate of Riga Polytechnic Institute, Engineer and Athlete Mārtiņš Stabiņš
2020
The aim of the article is to reveal the performance of Mārtiņš Stabiņš, a graduate of the Faculty of Automation and Computer Technology (1972; FACT) of Riga Polytechnic Institute (RPI), in the profession of engineer and high achievements in sports, becoming a Latvian champion in athletics several times, to reveal his daily life during his study years in the 1960s–1970s. Despite the fact that M. Stabiņš’ sports achievements have already described, this article summarizes his successes as well as reveals hitherto little-known and unpublished documents about his family, daily life, developments and interests. This is the first major research on the life of an engineer and athlete during seven …
Efficiency and Stability of a Family of Iterative Schemes for Solving Nonlinear Equations
2019
In this paper, we construct a family of iterative methods with memory from one without memory, analyzing their convergence and stability. The main aim of this manuscript yields in the advantage that the use of real multidimensional dynamics gives us to decide among the different classes designed and, afterwards, to select its most stable members. Some numerical tests confirm the theoretical results.
How to standardize (if you must)
2017
In many situations we are interested in appraising the value of a certain characteristic for a given individual relative to the context in which this value is observed. In recent years this problem has become prominent in the evaluation of scientific productivity and impact. A popular approach to such relative valuations consists in using percentile ranks. This is a purely ordinal method that may sometimes lead to counterintuitive appraisals, in that it discards all information about the distance between the raw values within a given context. By contrast, this information is partly preserved by using standardization, i.e., by transforming the absolute values in such a way that, within the s…
Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA
2016
International audience; RNA 2'-O-methylation is one of the ubiquitous nucleotide modifications found in many RNA types from Bacteria, Archaea and Eukarya. RNAs bearing 2'-O-methylations show increased resistance to degradation and enhanced stability in helices. While the exact role of each 2'-O-Me residue remained elusive, the catalytic protein Fibrillarin (Nop1 in yeast) responsible for 2'-O-methylation in eukaryotes, is associated with human pathologies. Therefore, there is an urgent need to precisely map and quantify hundreds of 2'-O-Me residues in RNA using high-throughput technologies. Here, we develop a reliable protocol using alkaline fragmentation of total RNA coupled to a commonly …
Smarter Open Government Data for Society 5.0: Are Your Open Data Smart Enough?
2021
Nowadays, governments launch open government data (OGD) portals that provide data that can be accessed and used by everyone for their own needs. Although the potential economic value of open (government) data is assessed in millions and billions, not all open data are reused. Moreover, the open (government) data initiative as well as users’ intent for open (government) data are changing continuously and today, in line with IoT and smart city trends, real-time data and sensor-generated data have higher interest for users. These “smarter” open (government) data are also considered to be one of the crucial drivers for the sustainable economy, and might have an impact on information and communi…
Selftype is a special case
1991
It is pointed out that selftype is actually only a special case of a construct that has been well described in the literature.
Graduate of Riga Polytechnic Institute, Athletics Statistician Andris Staģis
2020
The article summarizes the achievements of Andris Staģis, a graduate of the Faculty of Civil Engineering of Riga Polytechnic Institute (RPI; 1968), in the profession of an engineer, as well as reveals his contribution to the history and statistics of Latvian sports, achievements in athletics and their promotion. This is the first study on the activities and life of engineer, officer of the Order of the Three Stars, Latvian champion in athletics and the author of sports history books, and journalist A. Staģis. The aim of the research is to reveal the contribution of A. Staģis and the significance of his personality to Latvia using his and the authors’ personal archives, documents of the Stat…
Role of gemcitabine-based combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials.
2013
Background: Pancreatic cancer is the fourth leading cause of cancer-related death worldwide. Gemcitabine is the mainstay treatment for advanced disease. However, almost all up-to-date trials, that evaluated the benefit of gemcitabine-combination schedules, failed to demonstrate an improvement in overall survival (OS). In this study, we performed a systematic review and a meta-analysis of randomised clinical trials (RCTs) to investigate the efficacy and safety of gemcitabine-based combination regimens as compared to gemcitabine alone in the management of pancreatic cancer. Methods: Clinical trials were collected by searching different databases (PubMed, Embase and the Central Registry of Con…
Haploidentical Stem Cell Transplantation With Posttransplant Cyclophosphamide Therapy vs Other Donor Transplantations in Adults With Hematologic Canc…
2019
Question What are the outcomes of haploidentical stem cell transplantation with posttransplant cyclophosphamide therapy compared with other transplant types in adults with hematologic cancers? Findings In this meta-analysis of 30 studies including 22974 patients, the use of haploidentical stem cell transplantation with posttransplant cyclophosphamide therapy appeared to show increased all-cause mortality compared with matched related donors, similar all-cause mortality compared with matched unrelated donors, and reduced all-cause mortality compared with mismatched unrelated donors. Relapse appeared to be increased in lymphoma and similar in acute leukemia compared with matched unrelated don…