Search results for " Local"

showing 10 items of 2101 documents

Imaging photoplethysmography for clinical assessment of cutaneous microcirculation at two different depths

2016

The feasibility of bispectral imaging photoplethysmography (iPPG) system for clinical assessment of cutaneous microcirculation at two different depths is proposed. The iPPG system has been developed and evaluated for in vivo conditions during various tests: (1) topical application of vasodilatory liniment on the skin, (2) skin local heating, (3) arterial occlusion, and (4) regional anesthesia. The device has been validated by the measurements of a laser Doppler imager (LDI) as a reference. The hardware comprises four bispectral light sources (530 and 810 nm) for uniform illumination of skin, video camera, and the control unit for triggering of the system. The PPG signals were calculated and…

AdultPathologymedicine.medical_specialtyAdolescentBiomedical EngineeringLinimentHyperemiaCutaneous microcirculation02 engineering and technologyAdministration Cutaneous01 natural sciencesMicrocirculation010309 opticsBiomaterialsYoung AdultPhotoplethysmogram0103 physical sciencesImage Processing Computer-AssistedHumansMedicinePhotoplethysmographySkinbusiness.industryMicrocirculationEquipment DesignLaser Doppler velocimetryHand021001 nanoscience & nanotechnologyArterial occlusionAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic Materials0210 nano-technologybusinessPerfusionPreclinical imagingAnesthesia LocalBiomedical engineeringJournal of Biomedical Optics
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Proliferating tricholemmal tumour with lymph node metastases

1989

SUMMARY A 42-year-old woman with a proliferating tricholemmal tumour (PTT) with regional lymph node metastases is reported. Histochemical studies showed evidence of tricholemmal keratinization. There was recurrence following excision and subsequently the patient developed lymph node metastases.

AdultPathologymedicine.medical_specialtyScalpSkin Neoplasmsbusiness.industryDermatologymedicine.anatomical_structureLymphatic MetastasismedicineHumansKeratinsFemaleNeoplasm Recurrence LocalbusinessLymph nodeBritish Journal of Dermatology
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Innervated Island Flaps in Morphofunctional Vulvar Reconstruction

2000

In this article, the authors present their own experience in vulvar reconstruction following vulvectomy using two different innervated island flaps according to the size and site of the defect. Island-flap mobilization is possible thanks to the rich blood supply of the perineal region. The methods described are a "V-Y amplified sliding flap from the pubis" and a "fasciocutaneous island flap" raised from one or both gluteal folds. The V-Y amplified sliding flap from the pubis is indicated when the defect is symmetric and located anteriorly. This flap is harvested from the pubis and vascularized by the deep arterial network of the pubis. Sensory innervation is provided by branches of the ileo…

AdultReoperationMicrosurgeryReconstructive surgerymedicine.medical_specialtymedicine.medical_treatmentPudendal nerveIsland FlapsSurgical FlapsVulvamedicineHumansAgedNeoplasm StagingWound HealingVulvar NeoplasmsVulvectomybusiness.industrySuture TechniquesAnatomyMiddle AgedMicrosurgerySurgeryPlastic surgerymedicine.anatomical_structureRadical VulvectomyCarcinoma Squamous CellFemaleSurgeryNeoplasm Recurrence LocalbusinessPrecancerous ConditionsCarcinoma in SituPlastic and Reconstructive Surgery
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Ovarian Endometrioid-like Yolk Sac Tumor Treated by Surgery Alone, with Recurrence at 12 Years

1999

Abstract We describe the case of a stage Ia endometrioid-like yolk sac tumor (YST) of the ovary, which was originally misdiagnosed as a malignant struma ovarii and not treated with adjuvant chemotherapy. After 12 years, a contralateral dermoid cyst was excised along with a small omental nodule of partially necrotic and calcified endometrioid-like YST. No tumor was detected in several other biopsy specimens, and a peritoneal lavage was negative for tumor cells. Since there was no evidence of remaining tumor and the serum α-fetoprotein (AFP) level was normal after the second operation, the patient was followed. Serial serum AFP levels remained normal for 4 months. At a second-look laparotomy …

AdultReoperationPathologymedicine.medical_specialtyTime Factorsmedicine.medical_treatmentOvaryLaparotomyBiopsyHumansMedicineYolk sacPeritoneal NeoplasmsOvarian Neoplasmsmedicine.diagnostic_testbusiness.industryEndodermal Sinus TumorObstetrics and GynecologyMalignant Struma Ovariimedicine.diseaseSurgerymedicine.anatomical_structureOncologyDermoid cystFemaleHistopathologyNeoplasm Recurrence LocalPouchbusinessOmentumGynecologic Oncology
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Colon pouch (Mainz pouch III) for continent urinary diversion after pelvic irradiation

2000

Abstract Objectives. Urinary diversion after previous pelvic irradiation is challenging. The use of irradiated bowel in particular is associated with an increased rate of early and late complications. We therefore performed continent cutaneous urinary diversion using exclusively nonirradiated bowel segments in this group of patients. Methods. A continent colon pouch for urinary diversion was performed in 44 female patients after pelvic irradiation. The indications were irreparable vesical fistula in 20, local recurrence of gynecologic tumors in 22, and radical cystectomy for bladder cancer in 2 patients. Depending on the length of the nonirradiated bowel segment, a transverse-ascending colo…

AdultReoperationmedicine.medical_specialtyColonUrologymedicine.medical_treatmentUrologyUterine Cervical NeoplasmsUrinary DiversionAnastomosisCystectomyCloacaColon surgerymedicineHumansRadiation InjuriesAgedUpper urinary tractUrinary bladderVesicovaginal FistulaUrinary Bladder Fistulabusiness.industryAnastomosis SurgicalUrinary Reservoirs ContinentUrinary diversionMiddle AgedSurgeryTreatment Outcomemedicine.anatomical_structureFemaleNeoplasm Recurrence LocalPouchbusinessContinent Urinary DiversionFollow-Up StudiesUreteral ObstructionUrology
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Aneurysmal bone cyst of the spine in adult patients: A systematic review and comparison of primary vs secondary lesions.

2021

Background: Spine aneurysmal bone cysts (ABCs) rarely occur in adults. Primary and secondary lesions may show some differences and require appropriate treatments. Objective: To systematically review the literature on adult spine ABCs. Methods: PubMed, EMBASE, Scopus, and Web-of-Science were searched. Clinical-radiological features, treatments, and outcomes were analyzed and compared between primary vs secondary adult spine ABCs. Results: We included 80 studies comprising 220 patients. Primary spine ABCs were more frequent (76.4%). Main symptoms were lower-back-pain (42.8%) and motor deficits (31.2%). Tumors were mostly thoracic (31.4%) or cervical (26.8%), showing lytic (70.4%) and/or cysti…

AdultSettore MED/27 - NeurochirurgiaGeneral MedicineEmbolization TherapeuticSpineEmbolizationBone Cysts AneurysmalNeurologyAneurysmal bone cystPhysiology (medical)HumansSurgeryNeurology (clinical)DenosumabNeoplasm Recurrence LocalRetrospective StudiesJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
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Laparoscopic Radical Hysterectomy After Concomitant Chemoradiation in Locally Advanced Cervical Cancer: A Prospective Phase II Study

2015

Abstract Study Objective To assess the feasibility of total robotic radical surgery (TRRS) in patients with locally advanced cervical cancer (LACC) who receive chemoradiation therapy (CT/RT). Design A prospective (preplanned) study of a nonrandomized controlled trial (Canadian Task Force classification level 2). Setting Catholic University of the Sacred Hearth, Rome, Italy. Patients Between September 2013 and January 2016, a total of 40 patients with LACC (Federation Internationale de Gynecologie et d'Obstetrique stage IB2–III) were enrolled in the study. Interventions Robotic radical hysterectomy (RRH) plus pelvic and/or aortic lymphadenectomy was attempted within 6 weeks after CT/RT. The …

AdultUterine Cervical Neoplasmmedicine.medical_specialtymedicine.medical_treatmentUterine Cervical NeoplasmsHysterectomyPostoperative ComplicationsmedicineRadical hysterectomyHumansProspective StudiesCervical cancer; Laparoscopy; Neoadiuvant chemoradiation; Radical hysterectomy; Adult; Aged; Carcinoma; Squamous Cell; Chemoradiotherapy; Adjuvant; Cisplatin; Feasibility Studies; Female; Humans; Italy; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence; Local; Postoperative Complications; Prospective Studies; Uterine Cervical Neoplasms; Hysterectomy; Laparoscopy; Lymph Node ExcisionRadical surgeryRadical HysterectomyProspective cohort studyNeoadjuvant therapyAgedCervical cancerHysterectomybusiness.industryMedicine (all)Obstetrics and GynecologyLaparoscopic Radical HysterectomyPerioperativeChemoradiotherapy AdjuvantMiddle Agedmedicine.diseaseNeoadjuvant TherapySurgeryFeasibility StudieProspective StudieSettore MED/40 - GINECOLOGIA E OSTETRICIAItalyCervical cancerNeoadiuvant chemoradiationCarcinoma Squamous CellFeasibility StudiesLymph Node ExcisionLymphadenectomyFemaleLaparoscopyPostoperative ComplicationCisplatinNeoplasm Recurrence LocalbusinessHuman
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Association between obesity and vulvar cancer recurrence: an analysis of the AGO-CaRE-1 study

2020

ObjectiveObesity is associated with worse survival and an increased risk of relapse in several malignancies. The influence of obesity on vulvar cancer recurrence has not been previously described. The primary objective of this study was to evaluate the association between obesity and tumor recurrence in patients with vulvar cancer.MethodsThis is an analysis of the AGO-CaRE-1 study. Patients diagnosed with squamous cell vulvar cancer (stage IB and higher), treated in 29 cancer centers between January 1998 and December 2008, were registered in a centralized database. The cohort was divided into two gropus depending on the body mass index (BMI) (<30 vs ≥30 kg/m²). Descriptive statistics, su…

Adultmedicine.medical_specialtyBody Mass IndexYoung Adult03 medical and health sciences0302 clinical medicineQuality of lifeGermanyInternal medicinemedicineHumansObesityAgedNeoplasm StagingAged 80 and over030219 obstetrics & reproductive medicineVulvar Neoplasmsbusiness.industryObstetrics and GynecologyCancerMiddle AgedVulvar cancermedicine.diseaseObesityIncreased riskOncologyTime to recurrence030220 oncology & carcinogenesisCohortCarcinoma Squamous CellFemaleNeoplasm Recurrence LocalbusinessBody mass indexInternational Journal of Gynecologic Cancer
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Clinical, therapeutic and prognostic features of osteosarcoma of the jaws - experience of 36 cases.

2012

Abstract Introduction Osteosarcoma of the jaws (OSJ) differs from osteosarcoma of other skeletal regions due to later development, a high mortality associated with the local disease, fewer incidences of metastases and its extreme rarity. In regard to clinical and pathological parameters as well as therapeutic approaches and prognosis, OSJ has not been specifically examined to date. In order to achieve a better understanding of this special malignancy, an evaluation of incidence, treatment and prognosis of patients with OSJ in our department over the past 38 years was conducted. Materials and methods A retrospective analysis of patients with OSJ between 1972 and 2010 was performed. Informati…

Adultmedicine.medical_specialtyDelayed DiagnosisAdolescentmedicine.medical_treatmentMalignancyMetastasisYoung AdultCause of DeathGermanymedicineHumansChildSurvival rateNeoadjuvant therapyAgedRetrospective StudiesAged 80 and overOsteosarcomabusiness.industryIncidence (epidemiology)IncidenceRetrospective cohort studyMiddle Agedmedicine.diseasePrognosisJaw NeoplasmsNeoadjuvant TherapySurgeryOsteotomyRadiation therapySurvival RateOtorhinolaryngologyChild PreschoolOsteosarcomaSurgeryOral SurgeryNeoplasm Recurrence LocalbusinessFollow-Up StudiesJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
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Primary site disease and recurrence location in ovarian cancer patients undergoing primary debulking surgery vs. interval debulking surgery

2020

Introduction: The natural history and patterns of ovarian cancer (OC) relapse are still unclear. Recurrent disease can be peritoneal, parenchymal, or nodal. This study aims to analyze the location and pattern of OC recurrence according to the primary site of disease and to the type of surgical approach used. Material and methods: All OC patients underwent primary debulking surgery (PDS) or interval debulking surgery (IDS), with 2014 FIGO stage III-IV, and with platinum-sensitive recurrence were included in the study. Primary disease location and site of recurrences were divided into peritoneal, parenchymal, and nodal, according to the presence of peritoneal carcinomatosis, parenchymal metas…

Adultmedicine.medical_specialtyDiseaseMetastasis03 medical and health sciences0302 clinical medicineOvarian cancerRecurrenceMedicineHumans030212 general & internal medicineStage (cooking)Nodal involvementAgedOvarian Neoplasmsbusiness.industryGeneral MedicineCytoreduction Surgical ProceduresMiddle Agedmedicine.diseaseDebulkingSite of recurrencePeritoneal carcinomatosisSurgeryNatural historyNeoplasm RecurrenceOncologyLocalPrimary site location030220 oncology & carcinogenesisSurgeryFemaleNeoplasm Recurrence LocalPattern of recurrencebusinessOvarian cancer
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