Search results for " Local"
showing 10 items of 2101 documents
Identità locali e localismi autopropulsivi: sviluppo endogeno e derive localistiche nei modelli di sviluppo locale
2001
Image of a Local Area: Measuring and Managing
2018
The image of a local area can be conceived as cumulative beliefs, ideas, opinions, and experiences people have about a place. Image embodies a large number of information, memories, and suggestions that pertain to a specific place, which are processed by human mind by selecting relevant evidence from a big amount of data about a local area. Image conceptualizes the value and/or a certain level of performance that a place expresses and it inspires human behaviors. The image of a local area is perceiveid by people, it is part of knowledge structures related to a place and it is long-lasting and difficult to change. Measuring and managing the image of a local area can support the socioeconomic…
Dissection of human papillomavirus type 33 L2 domains involved in nuclear domains (ND) 10 homing and reorganization
2003
Abstract We have recently shown that the minor capsid protein L2 of human papillomavirus type 33 (HPV33) recruits the transcriptional repressor Daxx into nuclear domains (ND) 10 and causes the loss of the transcriptional activator Sp100 from these subnuclear structures (Florin et al., 2002b) . In order to dissect L2 domains involved in nuclear translocation, ND10 homing, loss of Sp100, and recruitment of Daxx, a detailed deletion mutagenesis of L2 was performed. Using immunofluorescence and green fluorescent protein fusions, we have identified two nuclear localization signals (NLS) in the central and C-terminal part of L2, respectively, homologous to previously identified NLS in HPV6B L2 (S…
Densità, complementarietà e qualità imprenditoriali per lo sviluppo locale
2017
Ricordo che da ragazzo provavo meraviglia quando, unendo con una matita i punti distribuiti su una pagina della Settimana Enigmistica, prendevano forma oggetti o animali. Da una distribuzione di punti, apparentemente casuale, man mano che procedevo unendo i punti, potevo intravedere il risultato finale. Il processo però era guidato da un sistema di numerazione e, infatti, a ogni punto era associato un numero. Unendo i punti seguendo la numerazione in ordine crescente, si vedeva emergere una forma che, a poco a poco, ero in grado di riconoscere. In questi anni mi sono reso conto che l’avvio di un’impresa, e anche la costruzione della nostra vita, è un percorso simile, così ci ha anche detto …
Selection bias ed incentivi alle imprese nei programmi per lo sviluppo locale: una valutazione ex-post
2015
This paper focuses on the evaluation of an aid scheme included in a larger local development program realized in Italy during the 2000-2006 cycle of EU Structural Funds. It follows a previous analysis (Cusimano, Mazzola, 2014) on the ex-post evaluation of the effects of the aid schemes included in the so-called territorial integrated projects (tips) and aims at identifying the possible presence of selection bias in measuring the effectiveness of the policy. After running an empirical analysis based on several propensity score matching (psm) methods, we show that, at least partially, the positive results previously obtained may not be related to an effective success of the policy, but could …
Un'analisi controfattuale degli incentivi agli investimenti infrastrutturali per lo sviluppo locale: il caso dei PIT
2016
Diagnóstico técnico sobre funciones urbanas y desarrollo territorial en Dénia. Aplicación de un sistema de indicadores
2022
El objetivo principal del trabajo que aquí se presenta es la elaboración de un diagnóstico técnico referido a las funciones urbanas, en consonancia con el modelo de desarrollo territorial de la ciudad de Dénia, sobre la base de un amplio sistema de indicadores orientado a conocer la eficiencia de la estructura urbana, sus infraestructuras y equipamientos específicos, así como los aspectos relativos a la calidad ambiental y de vida, la situación del urbanismo y la ordenación del territorio. La idea final es plantear el ámbito local como un territorio con capacidad para aportar ventajas competitivas a las empresas y calidad de vida a los ciudadanos. El diagnóstico trata de detectar aspectos q…
Los problemas de reestructuración de la siderurgia en la década de los ochenta y sus repercusiones en el proyecto de la IV Planta Siderúrgica Integra…
1983
XPO1 (Exportin-1) Is a Major Regulator of Human Erythroid Differentiation. Potential Clinical Applications to Decrease Ineffective Erythropoiesis of …
2015
Abstract Background We and others have shown that normal human erythroid cell maturation requires a transient activation of caspase-3 at late stages of maturation (Zermati et al, J Exp Med 2001). We further documented that, in human erythroblasts, the chaperone HSP70 is constitutively expressed and, at late stages of maturation, translocates into the nucleus and protects GATA-1, the master transcriptional factor critical for erythropoiesis, from caspase-3 cleavage (Ribeil et al, Nature 2007). During the maturation of human β-TM erythroblasts, HSP70 is sequestrated by excess of α-globin chains in the cytoplasm and as a consequence, GATA-1 is no longer protected from caspase-3 cleavage result…
Diffusive Modeling of Aggradation and Degradation in Artificial Channels
2008
The unsteady flow and solid transport simulation problem in artificial channels is solved using a three-equation model, coupled with a local erosion law. The three equations are the water mass and momentum balance equations, as well as the total solid load balance equation. It is shown that even during severe hydrological events inertial terms can be neglected in the momentum equation without any substantial change in the solution sought. Empirical equilibrium formulas were used to estimate the solid load as a function of the flow variables. Local erosion, due to the scour generated at the jump between two channels connected at different bottom elevations, was estimated adapting a literatur…