Search results for " Local"
showing 10 items of 2101 documents
Opinions: Corridor V scenarios through the eyes of the media
2008
Las Provincias en transición. Poder y prensa local en tiempos de cambio (1966-1982)
2017
El trabajo aborda el estudio de un medio de comunicación de gran influencia en la historia contemporánea valenciana, y entre su élite dirigente, la burguesía local exportadora y financiera. Las Provincias, diario fundado en 1866, adquirido al Marqués de Campo por Teodoro Llorente y el impresor José Doménech, ha pertenecido hasta su venta al grupo Vocento en 2000, a una misma familia de impresores y editores, los Doménech, y posteriormente hasta la actualidad, los Reyna Doménech y los Zarranz Doménech. El periódico, decano hoy de la prensa valenciana, ha vivido dos cambios de dinastía, dos repúblicas, una guerra civil y una dictadura y, tras la muerte de Franco, la transición política a la d…
El Corredor Mediterráneo
2016
El Corredor Mediterráneo, como proyecto de eje ferroviario, constituye un elemento clave de la planificación española y europea. Además de tener un papel de infraestructura de transporte, también cristaliza en cuestiones económicas y políticas a distintos niveles territoriales. Representa un cambio en la lógica de ordenación del territorio, al reforzar el eje litoral en detrimento de los enlaces radiales con la capital. En este libro se propone entender cómo el Corredor viene a ser un patente factor que incita a revisar el papel de los distintos actores implicados -políticos, económicos, institucionales...-, así como a reinterpretar los paradigmas de la ordenación del territorio e interroga…
Agri-urban patterns in Mediterranean urban regions: the case study of Pisa
2020
International audience; Urban regions require planning tools in order to manage agricultural areas under urban pressure. The aim of our paper is to test an analytical framework that combines both the composition in urban and agricultural land covers and their spatial configuration into four general agri-urban patterns: isolated fields, urban belt fields, periurban agricultural areas and rural areas. We evaluated the spatial distribution and the changes of such patterns in the short-term (2003-2011) starting from Spot images for the case study of Pisa, Italy. The results indicate an increase of the most urban patterns despite continuing to have cash crops, a stability of periurban agricultur…
First record of Synedropsis roundii (Bacillariophyta, Fragilariaceae) in the Mediterranean region
2019
Populations of the fragilarioid diatom Synedropsis roundii are described from the phytoplankton of the Albufera of Valencia, a large and shallow eutrophic lagoon in the Spanish Mediterranean coast. The specimens collected are described and illustrated with light and scanning electron microscopy. This is the first documented record of this species since its description, and the first illustrated record of the genus in the Mediterranean region. The Albufera lagoon and the type locality of the species (Imboassica Lagoon, SE Brazil) are similar in some ecological features. The ecological and biogeographical implications of this finding are briefly discussed.
Fluidizing the Membrane by a Local Anesthetic: Phenylethanol Affects Membrane Protein Oligomerization
2010
The exact mechanism of action of anesthetics is still an open question. While some observations suggest specific anesthetic-protein interactions, nonspecific perturbation of the lipid bilayer has also been suggested. Perturbations of bilayer properties could subsequently affect the structure and function of membrane proteins. Addition of the local anesthetic phenylethanol (PEtOH) to model membranes and intact Escherichia coli cells not only affected membrane fluidity but also severely altered the defined helix-helix interaction within the membrane. This experimental observation suggests that certain anesthetics modulate membrane physical properties and thereby indirectly affect transmembran…
A FE-Meshless Multiscale Approach for Masonry Materials
2015
Abstract A FE-Meshless multiscale computational strategy for the analysis of running bond masonry is presented. The Meshless Method (MM) is adopted to solve the boundary value problem (BVP) at the mesoscopic level. The representative unit cell is composed by the aggregate and the surrounding joints, the former assumed to behave elastically while the latter are simulated as non-associated elastic-plastic zero-thickness interfaces with a softening response. Macroscopic localization of plastic bands is obtained performing a spectral analysis of the tangent stiffness matrix. Localized plastic bands are embedded into the quadrature points area of the macroscopic finite elements.
Brain metabolism of ethanol and alcoholism: an update.
2007
It has long been suggested that some of the neuropharmacological, neurochemical and behavioural effects of ethanol are mediated by its first metabolite, acetaldehyde. In spite of the well documented psychoactivity of acetaldehyde, the precise role of this compound in alcohol abuse remains a matter of intense debate among scientists devoted to the study of alcoholism. Very frequently, the main drawback has been related to the presence of adequate levels of acetaldehyde or its derivatives inside the brain after ethanol ingestion. Since penetration into the central nervous system from blood of peripherically derived acetaldehyde is very low due to the high aldehyde dehydrogenase activity at th…
Isoflurane is associated with a similar incidence of emergence agitation/delirium as sevoflurane in young children ? a randomized controlled study
2006
Summary Background: Children may be agitated or even delirious especially when recovering from general anesthesia using volatile anesthetics. Many trials have focused on the newer agents sevoflurane and desflurane but for the widely used isoflurane little is known about its potential to generate agitation. We investigated the emergence characteristics of small children after sevoflurane or isoflurane with caudal anesthesia for postoperative pain control. Methods: After institutional approval and parental consent, anesthesia was randomly performed with sevoflurane (n = 30) or isoflurane (n = 29) in children at the age of 3.8 ± 1.8 years during surgical interventions on the lower part of th…
A New Nuclear Function of the Entamoeba histolytica Glycolytic Enzyme Enolase: The Metabolic Regulation of Cytosine-5 Methyltransferase 2 (Dnmt2) Act…
2009
Cytosine-5 methyltransferases of the Dnmt2 family function as DNA and tRNA methyltransferases. Insight into the role and biological significance of Dnmt2 is greatly hampered by a lack of knowledge about its protein interactions. In this report, we address the subject of protein interaction by identifying enolase through a yeast two-hybrid screen as a Dnmt2-binding protein. Enolase, which is known to catalyze the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), was shown to have both a cytoplasmatic and a nuclear localization in the parasite Entamoeba histolytica. We discovered that enolase acts as a Dnmt2 inhibitor. This unexpected inhibitory activity was antagonized by…