Search results for " Low"
showing 10 items of 972 documents
Low molecular weight heparins as antineoplastic agents.
2008
There is an increasing interest in the potential role of low molecular weight heparins (LMWHs) in the management of cancer patients. These antithrombotic agents have generated particular excitement because they have been proved useful in both the prevention and treatment of venous thromboembolism (VTE) in patients with malignancy. Recent reports are, at the same time, highlighting a potential role of LMWHs on patient survival due to their presumed antineoplastic action. This review will discuss the most recent reports and patents on these topics.
Fundamental Research in Oncology and Thrombosis 2 (FRONTLINE 2): A Follow‐Up Survey
2020
Abstract Background Fundamental Research in Oncology and Thrombosis (FRONTLINE) is a global survey of physicians' perceptions and practice in the management of venous thromboembolism (VTE) in patients with cancer. Materials and Methods The present survey, FRONTLINE 2, follows the original FRONTLINE survey (published in The Oncologist in 2003) and provides insights into how physicians perceive risk of VTE in cancer and approach its prophylaxis and treatment. Results Between November 2015 and February 2016, 5,233 respondents participated, representing cancer physicians and surgeons. Most believed that less than one in five patients with any cancer might be at risk of VTE, with a slightly high…
Risk of pancreatic malignancy and mortality in branch-duct IPMNs undergoing surveillance: A systematic review and meta-analysis
2016
Abstract Background Safety of non-operative management for low-risk branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) is debated. Aim To perform a systematic review/meta-analysis to determine their risk of developing pancreatic malignancy and of pancreatic malignancy-related deaths. Methods A MEDLINE search was performed and methodology was based on PRISMA statement. Incidence rates of overall pancreatic malignancy, malignant BD-IPMN, IPMN-distinct PDAC, and of pancreatic malignancy-related death rates were calculated by dividing the total number of events by the total number of person-years (pyrs) of follow-up. Heterogeneity was determined by I2 statistic. Results 20 studies …
Second follow-up of a German cohort on childhood cancer incidence after exposure to postnatal diagnostic x-ray.
2019
Studies on children exposed to ionizing radiation by computed tomography (CT) indicate an increased risk of leukemia and central nervous system (CNS) tumors. Evidence of the risks associated with diagnostic X-ray examinations, the most frequent examination in pediatric radiology, in which the radiation dose is up to 750 times lower compared to CT examinations, is less clear.a#13; This study presents results of the second follow-up for the risk of childhood cancer in a cohort of children (alt;15 years) with diagnostic X-ray exposure at a large German hospital during 1976-2003 followed for additional 10 years until 2016.a#13; With a latency period of six months, 92,998 children contributed 79…
One-step reactive processing of low density polyethylene and octavinyl polyhedral oligomeric silsesquioxane
2015
Polyhedral oligomeric silsesquioxane (POSS) are an innovative class of organosilicon compounds suitable for formulation of advanced organic-inorganic hybrid materials. Nanocomposites based POSS found application mostly in high-temperature resistance and fire-resistance materials. POSS are characterized by a three dimensional cage-like structure, made of Si-O bonds, with different organic groups directly linked to the Si atoms of the cage structure. The organic groups can be designed to facilitate the dispersion of the nanoparticle itself in the polymer matrix or also to react with the polymer chain. This work focuses on the possibility to obtain crosslinking of polyethylene using octavinyl-…
An Analytic Hierachy Process for Ranking Operating Costs of Low Cost and Full Service Airlines
2009
This paper develops an application of the analytic hierarchy process to rank the operating cost components of full service and low cost airlines. It takes into account the financial balance sheets and answers to a questionnaire submitted to the managers of selected airlines. The results suggest that the analytic hierarchy process can be appropriately used to obtain the ranking of the costs taking into account different views: financial, management and operative. Rental, office equipment and other supplies costs show the highest importance in the cost ranking, both for full services and low cost airlines. The robustness of the results is tested by Monte Carlo analysis.
O utworzeniu Parku Narodowego "Puszcza Śląska"
2016
National Park is in Рolish law one of the most important protection form that is dedicated to areas sustained in natural conditions, having fairly untouched vegetation and biodiversity. Despite that the Silesian Forest-Nature District has a unique areas in terms of nature values as well as cultural and biodiversity heritage, no national parks were established here until now. In the proposed national park of Silesian Forest 50 legally protected plant species were noted, in this 16 listed as threatened in Polish Red Data Book. More than 130 plant species were found rare within the area. Approximately 250 legally protected animal species are found within park borders that are permanent residen…
On the optimal design of multi-stage cascaded transistor amplifiers with noise, gain and mismatch constraints
2007
The problem of evaluating the optimal performances of cascaded, unbalanced, multi-stage transistor amplifiers is addressed. In particular, a theoretically rigorous approach is proposed for the determination of a family of Optimal Design Curves (ODC's) which express the best noise-gain tradeoff that can be achieved - at each frequency and device operating condition - when a simultaneous constraint on amplifier input VSWR is accounted for. Such curves can be used as a more meaningful starting point in practical amplifier design in place of the approximate calculations so far employed for target performance or optimization goals determination.
Computational methods for optimal shakedown design of FE structures
1998
The paper concerns the optimal shakedown design of structures discretized by elastic perfectly plastic finite elements. The design problem is formulated in four alternative versions, i.e. as the search for the minimum volume design whose shakedown limit load multiplier is assigned or as the search for the maximum shakedown limit load multiplier design whose volume is assigned; both problems are approached on the grounds of the shakedown lower bound and upper bound theorems. Correspondingly four computational methods, one for each original problem, are presented. These methods consist in solving iteratively new problems which are simpler than the original ones, but expressed in such a way th…
Optimal shakedown design of beam structures
1994
The optimal design of plane beam structures made of elastic perfectly plastic material is studied according to the shakedown criterion. The design problem is formulated by means of a statical approach on the grounds of the shakedown lower bound theorem, and by means of a kinematical approach on the grounds of the shakedown upper bound theorem. In both cases two different types of design problems are formulated: one searches for the minimum volume design whose shakedown limit load is assigned; the other searches for the design of the assigned volume whose shakedown limit load is maximum. The optimality conditions of the four problems above are found by the use of a variational approach; such…