Search results for " MIG"
showing 10 items of 1654 documents
Cellul�re Immunreaktionen gegen�ber homologen leberspezifischen Antigenen (HLP) bei chronischen Leberentz�ndungen
1974
Es wird eine Zweiphasentechnik des Leukocyten-Migrations-Inhibitionstestes beschrieben und zum Nachweis einer cellularen Immunreaktion gegenuber Leberantigenen bei chronisch-entzundlichen Lebererkrankungen eingesetzt. Mit dieser Technik wurde bei 85% der Patienten mit hypergammaglobulinamischer Verlaufsform einer chronisch-aktiven Hepatitis und 42% der Patienten mit aktiv fortschreitenden kryptogenen Lebercirrhosen eine Migrationshemmung nachgewiesen. Lebergesunde Kontrollen zeigten keine, Patienten mit dem Zustand nach Hepatitis und chronisch-persistierender Hepatitis selten eine Leukocytenmigrationsinhibition gegenuber leberspezifischen Antigenen. 17% der Patienten mit chronisch-aktiver H…
Bidding for Research Funds. Inter-Fields Differences and Predictors of the Evaluation Scores: Insights from a Romanian National Competition for Postd…
2021
This study sought to address an important gap in the existent knowledge about the development of the Romanian research system by looking at a very specific population of young scholars who participated in the national competition for postdoctoral grants (2016) which included over 900 participants. The paper is structured by two main research objectives. Firstly, the analysis if focused on differences between scientific fields by looking at research entities which host young scholars’ grant proposals, gender balance, young scholars’ academic performance measured through a standardized indicator (Google Scholar H index), share of people trained abroad, and information about the evaluation pro…
Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro
2010
Oral Diseases (2011) 17, 194–199 Objectives: Bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) is a side effect in patients being treated with bisphosphonates. The bisphosphonates most often associated with BP-ONJ are the highly potent nitrogen-containing bisphosphonates, e.g. pamidronate or zoledronate. In terms of BP-ONJ aetiology, several theories are being discussed: inhibition of bone remodelling, effect on soft tissues, and antiangiogenic effect of bisphosphonates. The aim of this in vitro study was to investigate the effect of different potent bisphosphonates on osteoblasts, fibroblasts and human umbilicord vein endothelial cells (HUVEC). Materials and methods: Three nitr…
Anti-Human CD9 Fab Fragment Antibody Blocks the Extracellular Vesicle-Mediated Increase in Malignancy of Colon Cancer Cells.
2022
Intercellular communication between cancer cells themselves or with healthy cells in the tumor microenvironment and/or pre-metastatic sites plays an important role in cancer progression and metastasis. In addition to ligand–receptor signaling complexes, extracellular vesicles (EVs) are emerging as novel mediators of intercellular communication both in tissue homeostasis and in diseases such as cancer. EV-mediated transfer of molecular activities impacting morphological features and cell motility from highly metastatic SW620 cells to non-metastatic SW480 cells is a good in vitro example to illustrate the increased malignancy of colorectal cancer leading to its transformation and aggressive b…
Cardiovascular Health in Migrants. Current status and issues for prevention. A Collaborative Multidisciplinary Task Force Report
2014
OBJECTIVES: To review information on cardiovascular health and migration, to stress the attention of researchers that much needs to be done in the collection of sound data in Italy and to allow policy makers identifying this issue as an important public health concern. BACKGROUND: In Italy, the rate of immigrants in the total number of residents increased from 2.5% in 1990 to 7.4% in 2010, and currently exceeds 10% in regions such as Lombardia, Emilia Romagna and Toscana. METHODS: A consensus statement was developed by approaching relevant Italian national scientific societies involved in cardiovascular prevention. Task force members were identified by the president and/or the boards of eac…
REAL HUMANS? : Affective imaginaries of the human and its Others in the Swedish TV series Äkta människor
2019
According to the Swedish science fiction TV series Äkta människor (Real Humans, SVT and Matador film 2012-2014), humanoid robots called “hubots” are replacing the human workforce in care work and assembly line industries. Against the backdrop of current debates about immigration and citizenship in the Nordic countries, this article does a close, contextual reading of the series, exploring how the hubots influence work and family life. We are particularly interested in how hubots tie in with the cultural circulation of affect in relation to Otherness and how responses towards the “not-quite” human or dehumanized Other are negotiated in the present-day Nordic cultural imaginaries. What kinds …
Kvalificētu veselības aprūpes speciālistu migrācija starp Latviju un ārvalstīm: Emigrācijas un reemigrācijas cēloņu analīze
2021
Bakalaura darbs “Kvalificētu veselības aprūpes speciālistu migrācija starp Latviju un ārvalstīm: Emigrācijas un reemigrācijas cēloņu analīze” aplūko migrācijas tendences minētajā cilvēku grupā periodā no 2000. līdz 2020. gadam. Satraukumu izraisošos emigrantu apjomus, kā arī salīdzinoši zemo reemigrantu skaitu ir nepieciešams izlīdzināt, lai migrācijas tendences nosūtītājvalstij nāktu par labu, nevis ietekmētu to negatīvi. Darba mērķis ir noskaidrot un analizēt emigrācijas un reemigrācijas cēloņus veselības aprūpes speciālistu vidū, kuri veido emigrācijas un potenciāli reemigrācijas plūsmu no Latviju uz ārvalstīm un atpakaļ. Autores pētījums noskaidro esošo un topošo veselības aprūpes speci…
The Status of EGFR Modulates the Effect of miRNA-200c on ZEB1 Expression and Cell Migration in Glioblastoma Cells
2020
Migration of glioblastoma cells into surrounding tissue is one of the main features that makes this tumor incurable. We evaluated whole-genome miRNA expression profiling associated with different EGFR amplification patterns in 30 cases of primary glioblastoma. From the 64 miRNAs that showed differential expression between tumors with a high level of EGFR amplification and tumors without EGFR amplification, 40% were related with cell migration, being miR-200c the most differentially expressed between these two groups. We investigated the effect of miR-200c on ZEB1 expression and cell migration in an in vitro transfection model with a miR-200c mimic, a miR-200c inhibitor and siRNA targeting E…
In vivo imaging and quantification of the continuous keratin filament network turnover
2008
Keratin polypeptides are major components of the epithelial cytoskeleton forming a filamentous 3D-network. Like intermediate filament polypeptides of other cell types, keratins make up a stable, but elastic network that is responsible for mechanical stress resilience. At the same time the keratin network is able to change its shape during development, cell division, metastasis and cell migration.
Molecular and isotopic composition of free hydrocarbon gases from Sicily, Italy
2004
[1] Chemical and isotopic data have been used as geochemical tracers for a genetic characterization of hydrocarbon gases from a total of eleven manifestations located in Eastern and Central-Southern Sicily (Italy). The molecular analysis shows that almost all the samples are enriched in methane (up to 93.2% Vol.), with the exception of four gas samples collected around Mt. Etna showing high mantle-derived CO2 content. Methane isotope signatures suggest that these are thermogenic gases or a mixture between thermogenic gases and microbial gases. Although samples from some mud volcanoes in Southern Sicily (Macalube di Aragona) show isotope signatures consistent with a mixing model between ther…