Search results for " MODELLI"

SIMULATING DEMOGRAPHY AND HUMAN DEVELOPMENT DYNAMICS

2014

[EN] A deterministic/stochastic model in which the demographic and the well-being subsystems of a country are involved and related is presented as a way to approach human development. The demographic subsystem is a side-by-side, single-gender, age-structured population dynamic model. The well-being subsystem states the dynamics of the United Nations Hybrid Human Development Index. The model has been validated in the case of Spain and Belgium. Some simulations have been performed with the model for the case of Spain in the 2009-2020 period to determine strategies and scenarios that could increase the life expectancy at birth per gender. Copyright © 2014 Taylor & Francis Group, LLC.

A Stochastic Model for Population and Well-Being Dynamics

2014

This article presents a stochastic dynamic model to study the demographic evolution per sexes and the corresponding well-being of a general human population. The main model variables are population per sexes and well-being. The considered well-being variable is the Gender-Related Development Index (GDI), a United Nations index. The model's objectives are to improve future well-being and to reach a stable population in a country. The application case consists of adapting, validating, and using the model for Spain in the 2000–2006 period. Some instance strategies have been tested in different scenarios for the 2006–2015 period to meet these objectives by calculating the reliability of the res…

Quantifying Excess Deaths Related to Heatwaves under Climate Change Scenarios: A multicountry time series modelling study

2018

Background: Heatwaves are a critical public health problem. There will be an increase in the frequency and severity of heatwaves under changing climate. However, evidence about the impacts of climate change on heatwave-related mortality at a global scale is limited. Methods and findings: We collected historical daily time series of mean temperature and mortality for all causes or nonexternal causes, in periods ranging from January 1, 1984, to December 31, 2015, in 412 communities within 20 countries/regions. We estimated heatwave–mortality associations through a two-stage time series design. Current and future daily mean temperature series were projected under four scenarios of greenhouse g…

Stability and Change in Diffusion Model Parameters over Two Years

2021

In recent years, mathematical models of decision making, such as the diffusion model, have been endorsed in individual differences research. These models can disentangle different components of the decision process, like processing speed, speed–accuracy trade-offs, and duration of non-decisional processes. The diffusion model estimates individual parameters of cognitive process components, thus allowing the study of individual differences. These parameters are often assumed to show trait-like properties, that is, within-person stability across tasks and time. However, the assumption of temporal stability has so far been insufficiently investigated. With this work, we explore stability and c…

The discovery of new inhibitors of HIF-1 transcriptional activity by virtual screening

2010

Searching for long-lived particles beyond the Standard Model at the Large Hadron Collider

2020

Particles beyond the Standard Model (SM) can generically have lifetimes that are long compared to SM particles at the weak scale. When produced at experiments such as the Large Hadron Collider (LHC) at CERN, these longlived particles (LLPs) can decay far from the interaction vertex of the primary proton–proton collision. Such LLP signatures are distinct from those of promptly decaying particles that are targeted by the majority of searches for new physics at the LHC, often requiring customized techniques to identify, for example, significantly displaced decay vertices, tracks with atypical properties, and short track segments. Given their non-standard nature, a comprehensive overview of LLP…

3D-QSAR study of ligands for two human olfactory receptors

2007

National audience

Meta-Analysis of Mitochondrial DNA Reveals Several Population Bottlenecks during Worldwide Migrations of Cattle

2014

Several studies have investigated the differentiation of mitochondrial DNA in Eurasian, African and American cattle as well as archaeological bovine material. A global survey of these studies shows that haplogroup distributions are more stable in time than in space. All major migrations of cattle have shifted the haplogroup distributions considerably with a reduction of the number of haplogroups and/or an expansion of haplotypes that are rare or absent in the ancestral populations. The most extreme case is the almost exclusive colonization of Africa by the T1 haplogroup, which is rare in Southwest Asian cattle. In contrast, ancient samples invariably show continuity with present-day cattle …

Pluvial flooding in urban areas: the role of surface drainage efficiency

2018

Pluvial flooding in urban areas may derive from the limited or temporarily reduced efficiency of surface drainage, even when the underlying storm sewers are properly designed. This study focuses on the impact of uncertainties in the operational condition of the surface drainage system on pluvial flood hazard. The flood propagation model FLURB-2D is implemented on a selected study area in the town of Genoa (Italy). Synthetic hyetographs based on the Chicago and bivariate copula methods with suitable return periods are used as input. While simulating the design rainfall, inlet operational conditions are varied stochastically using a Monte Carlo approach. Results confirm that microtopography h…

The Occurrence and Dietary Exposure Assessment of Mycotoxins, Biogenic Amines, and Heavy Metals in Mould-Ripened Blue Cheeses

2020

The occurrence and dietary exposure assessment of 16 mycotoxins, 6 biogenic amines (BAs), and 13 metallic elements in blue-veined cheeses (n = 46) is reported. Co-occurrence of mycophenolic acid (&le