Search results for " MODELS"
showing 10 items of 4240 documents
C5a complement and cytokine signaling mediate the pronociceptive effects of complex regional pain syndrome patient IgM in fracture mice.
2020
It has been proposed that complex regional pain syndrome (CRPS) is a posttraumatic autoimmune disease. Previously, we observed that B cells contribute to CRPS-like changes in a mouse tibia fracture model, and that early (12 months duration) CRPS patient IgM antibodies have pronociceptive effects in the skin and spinal cord of muMT fracture mice lacking B cells. The current study evaluated the pronociceptive effects of intraplantar or intrathecal injections of early CRPS IgM (5 µg) in muMT fracture mice. Skin and lumbar spinal cord were collected for immunohistochemistry and polymerase chain reaction analyses. Wild-type mice exhibited postfracture increases in complement component C5a and it…
Asiantuntijat uusien toimintamallien oppijoina
2003
Työ muuttuu ja sitä kautta myös työssä tarvittavien toimintatapojen pitäisi muuttua. Ajattelumallien tai toimintatapojen muuttaminen ei ole aina helppoa, sillä käytössä olevat mallit rutinoituvat nopeasti. Ihmisillä ei ole kykyä, halua tai aikaa tarkastella omaa työtään uusien silmälasien läpi, arvioida tapojensa toimivuutta tai jopa kokonaan kyseenalaistaa niiden järkevyyttä. Mielenkiintoisen ratkaisun etsiä uusia toimintamalleja ennakkoluulottomasti edustaa seuraava esimerkki Englannista. – Artikkelissa kuvataan brittiläisessä sairaalassa toteutettua kehittämisprosessia, jossa lääkärien visuaalisen hahmottamisen apuna on käytetty taiteilijoita.
ADAPT - Advanced Prediction Models for Trajectory-Based Operations (TBO)
2018
Continuous subcutaneous Insulin infusion leads to immediate, table, and long-term changes in metabolic control
2008
Background: Evaluations of continuous subcutaneous insulin infusion (CSII) usually focus on one pre- and one post-CSII measurement to assess metabolic therapy outcome. Aim: Extending this research, the aim of the present study was to provide a more fine-grained analysis of achieved glycaemic control. Methods: In 52 patients with type 1 diabetes (mean age of 37.85 years at CSII begin; s.d. ± 12.41), haemoglobin A1c (HbA1c) levels were assessed every 3 months over a period of 5 years (1 year before and 4 years after the introduction of CSII). Mixed models were utilized to describe changes in glycaemic control. Results: The pre–post course showed that already in the first quarter, a statis…
Effects of Transcranial Direct Current Stimulation on Baseline and Slope of Prefrontal Cortex Hemodynamics During a Spatial Working Memory Task
2020
Background: Transcranial direct current stimulation (tDCS) has been shown to be an inexpensive, safe, and effective way of augmenting a variety of cognitive abilities. Relatively recent advances in neuroimaging technology have provided the ability to measure brain activity concurrently during active brain stimulation rather than after stimulation. The effects on brain activity elicited by tDCS during active tDCS reported by initial studies have been somewhat conflicted and seemingly dependent on whether a behavioral improvement was observed. Objective: The current study set out to address questions regarding behavioral change, within and between-participant designs as well as differentiatin…
The use of diagnostic tools in GAMLSS for liver fibrosis detection
Modélisation des choix d'itinéraires pédestres en milieu urbain. Approche géographique et paysagère
2006
Nowadays, on foot journeys create renewed interest as a complementary mode of transport. Indeed, local decision makers appear as willing to reduce the imbalance between different ways of transport within the cities. In the field of Geography the term ‘mobility' refers to the practice of exchanges and movements done by individuals or groups of individuals; this mobility is likely to reveal the characteristics of places and to contribute to their alteration. Among all the modes of transport, walking implies a privileged relation between persons and area they live in. As an element of the living environment used on a daily basis and eventually integrated by the prism of perception the visible …
Clickstream Data Analysis: A Clustering Approach Based on Mixture Hidden Markov Models
2023
Nowadays, the availability of devices such as laptops and cell phones enables one to browse the web at any time and place. As a consequence, a company needs to have a website so as to maintain or increase customer loyalty and reach potential new customers. Besides, acting as a virtual point-of-sale, the company portal allows it to obtain insights on potential customers through clickstream data, web generated data that track users accesses and activities in websites. However, these data are not easy to handle as they are complex, unstructured and limited by lack of clear information about user intentions and goals. Clickstream data analysis is a suitable tool for managing the complexity of t…
On the volumetric response of a compacted clay subjected to wetting and drying cycles
2009
Experimental evidence on the volumetric response of a compacted clay was collected in controlled suction oedometric tests, with the aim to assess the volumetric response of this soil when subjected to wetting and drying cycles. The overall soil behaviour seems mainly to depend on the double structural arrangement observed in the compacted specimens. Selected results are presented and discussed focusing on the influence of the stress history on the volumetric response. Test results are simulated by a double-structure suction-dependent elasto-plastic constitutive model, in which the mechanical response is related to micro and macrostructural deformations and their mutual interactions. The pro…
El control de la comprensión de textos científicos en inglés como lengua extranjera, en estudiantes universitarios españoles no bilingües : evaluació…
2013
'Esta tesis presenta un estudio sobre el uso de estrategias metacognitivas y su impacto en la comprensión lectora en inglés como LE de estudiantes universitarios españoles. Se analiza dónde se encuentran las deficiencias, en su caso, y cómo pueden ser superadas mediante intervenciones didácticas apropiadas. Los estudios empíricos realizados se agrupan en tres grandes bloques. El primer bloque está dedicado a la caracterización de los estudiantes universitarios en lo que respecta a su competencia lectora en inglés. Un primer estudio evalúa el dominio lingüístico en inglés y las principales dificultades que presentan estos estudiantes para poder comunicar y comprender ideas básicas en esta le…