Search results for " Macro"
showing 10 items of 522 documents
Zur Geschichte der nacheiszeitlichen Umwelt und der Kulturpflanzen im Land Brandenburg
2018
International audience; The results of pollenanalytical and archaeobotanical studies presented here show the development of veg-etation in the state of Brandenburg, which was characterized by the climate and the associated natural spread of plants as well as the use of the resource forest by man.The plant food of humans was first obtained by gathering and, since the beginning of permanent settle-ment in the Neolithic period, mainly by means of agriculture. The cultivation of plants continued over the millennia, with most archaeological cultures showing their typical inventory of crops. The dynamics of these developments require further research, as there are still many spatial and temporal …
Microglia and α-synuclein implication in Parkinson's disease
2011
Age-related neurodegenerative disorders like Parkinson’s disease take an enormous toll on individuals and on society. Despite extensive efforts, Parkinson’s disease remains incurable and only very limited treatments exist. Indeed, Parkinson’s pathogenesis is still not clear and research on its molecular mechanisms is ongoing. In this study, we focused our interest on two abnormal events occurring in Parkinson’s patients, namely α-synuclein aggregation and microglial activation. We first investigated α-synuclein and its abnormal polymerisation. For this purpose, we developed novel methods, which allowed the in vitro production of different types of α-synuclein oligomers. Using highly sensiti…
Utilisation en grand cours d'eau de l'Indice Biologique Macrophytique en Rivière. Comparaison avec une approche typologique, mise en évidence des per…
2004
Utilisation en grand cours d'eau de l'Indice Biologique Macrophytique en Rivière. Comparaison avec une approche typologique, mise en évidence des perturbations du profil longitudinal. Colloque AFL
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
2016
Seuls les 100 premiers auteurs dont les auteurs INRA ont été entrés dans la notice. La liste complète des auteurs et de leurs affiliations est accessible sur la publication.; International audience; In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues…
La cuisine d’une maison de maître du Haut-Empire à Grand (Vosges)
2013
During excavations conducted in 2011 in Grand (Vosges), a domus dating from the 2nd century and the first half of the 3rd was uncovered. Among the well-preserved vestiges a kitchen was identified with its cooking installations still in situ. These consisted of a hearth, a raised cooking platform and an oven. The kitchen was probably in use for both the residential and the servant’s quarters of the domus. The sediments linked to the use of the kitchen yielded numerous organic remains and pottery sherds dating from the 3rd century. These finds document, at least partially, the kitchenware in use, diet and waste management practices in use in this household. The kitchen stands out as a place t…
Éducation, formation et choix technologiques : un modèle macro économique sur le cas de l'Équateur
1988
International audience
Une approche macro-économétrique interrégionale appliquée de la solidarité entre les territoires français
1996
International audience; Redistribution among French region : an interregional macro-modelling essay. First we start on a general survey of French regional economic equilibrium in a dualistic sense : is there any convergence between Paris region and the other parts of the national territory ? Things must be considered separately as they involve primary allocation (wages, entrepreneurial revenue) or redistribution process. On the medium term the redistribution bonus is more and more oriented towards non central regions, partly due to economic reason but also as an impact of national income policies. After a general summary of the modelling process uses here as a tool, we present some macro-ev…
Calcul des risques et rationalité dans la pensée de Cesare Beccaria
2000
International audience; Le traité de Beccaria Des délits et des peines fut publié entre avril et juillet 1764 au moment où paraissaient les premières feuilles du Café 1. Il est donc à peu près contemporain de l'essai d'analyse sur la contrebande que Beccaria rédigea pour le périodique de Pietro Verri. Cet article est assez peu commenté pour des raisons qui sont simples : il s'agit d'un texte bref (une page et demie) ; le sujet traité est une question technique (la méthode de fixation d'un tarif douanier). Beccaria enfin recourt aux mathématiques en utilisant des symboles et une forme de fonction qui ne sont pas ceux des manuels d'aujourd'hui 2. Pourtant l'article nous paraît typique de la r…
Modèle global et paramétrable, pour la gestion des foules d'agents en animation comportementale
2011
The realism of crowd behavioral animation is based on one hand on a rendering of graphic scenes generated by the application, and on the other hand on the realism of the behavior. This is last point which is our object of study. The realism of crowds' behavior is essentially global (macroscopic realism). It must respect the required statistical characteristics of the crowd (density, dispersal, speed…) similar to those of a real crowd. The realism is also local (microscopic realism), i.e. agents should ideally behave like humans or human groups taken as reference, at least in the focus of the considered application. The aim of our research is to propose a generic model to perform crowd behav…
Study of acoustic properties and impact behavior of porous materials homogeneous type metal foams and inhomogeneous
2015
This work is concerned with the theoretical and experimental study of the acoustical properties of macroscopically homogenous and inhomogeneous porous media as well as their mechanical response to impacts. The model of Johnson - Champoux - Allard appeared adapted for the acoustical modeling. This model, associated with a recently developed approach involving the concept of parallel transfer matrices has lead to a new approach of macroscopically inhomogeneous porous materials based on “mixtures of materials”. Furthermore, a parametric study of the absorption coefficient as a function of porosity and frequency has been proposed. The maximums of absorption as well as the envelop of the absorpt…