Search results for " Mapping"
showing 10 items of 1411 documents
Bayesian Analysis of Population Health Data
2021
The analysis of population-wide datasets can provide insight on the health status of large populations so that public health officials can make data-driven decisions. The analysis of such datasets often requires highly parameterized models with different types of fixed and random effects to account for risk factors, spatial and temporal variations, multilevel effects and other sources on uncertainty. To illustrate the potential of Bayesian hierarchical models, a dataset of about 500,000 inhabitants released by the Polish National Health Fund containing information about ischemic stroke incidence for a 2-year period is analyzed using different types of models. Spatial logistic regression and…
Localization of non-specific X-linked mental retardation gene (MRX73) to Xp22.2.
2001
Clinical and molecular studies are reported on a family (MRX73) of five males with non-specific X-linked mental retardation (XLMR). A total of 33 microsatellite and RFLP markers was typed. The gene for this XLMR condition was been linked to DXS1195, with a lod score of 2.36 at theta = 0. The haplotype and multipoint linkage analyses suggest localization of the MRX73 locus to an interval of 2 cM defined by markers DXS8019 and DXS365, in Xp22.2. This interval contains the gene of Coffin-Lowry syndrome (RSK2), where a missense mutation has been associated with a form of non-specific mental retardation. Therefore, a search for RSK2 mutations was performed in the MRX73 family, but no causal muta…
Student Author of the Year Award 2009
2009
The ‘‘Student author of the Year Award’’ is made for an outstanding paper in which an undergraduate or graduate student played a key role in the research and publication. The recipient of this award for 2009 is Ruben Diez Fernandez for his contribution, co-authored with Jose R. Martinez Catalan 3D Analysis of an Ordovician igneous ensemble: A complex magmatic structure hidden in a polydeformed allochthonous Variscan unit Journal of Structural Geology, Volume 31, Issue 3, March 2009, Pages 222–236. The Editors have selected this paper out of many student submissions in 2009. The basis of this paper is detailed field mapping, metamorphic petrology and structural analysis. These clearly establ…
Simultaneous atrial and ventricular restitution and fibrillation analyses using a low-cost scalable panoramic whole-heart optical mapping configurati…
2021
Abstract Introduction Optical mapping (OM) is the primary method for imaging electrophysiologically relevant parameters from the outer surface of Langendorff-perfused hearts. However, current panoramic OM systems are financially challenging, require multiple sensors to map wide areas of the surface with overlapping regions and missing areas of interest due to the intrinsic shape of the heart. We proposed different panoramic configurations to dynamically characterize atrial and ventricular function during arrhythmia and, in presence of a coronary occlusion. Methods We devised both a multi-sensor and a single sensor system integrated with the perfusion circuit comprising sensor elements, a co…
Synchrony Analysis of Unipolar Cardiac Mapping during Ventricular Fibrillation
2014
Ventricular Fibrillation (VF) is one of the main causes of death in developed countries. Recent studies have shown that fibrillation have a complex organization scheme. This work uses three measures of synchrony to characterize three groups of rabbit hearts. These groups consist of rabbits trained with physical exercise (N=7), untrained rabbits treated with a drug (N=13) and a control group of untrained rabbits (N=15). Cardiac mapping records were acquired using a 240-electrode array placed on left ventricle of isolated rabbit hearts, and VF was induced pacing at increasing rates. Two acquisitions were performed: maintained perfusion, and ischemic damage produced by an artery ligation. The …
A Decision Model on Corporate Social Responsibility and Business Strategies
2017
The role of companies in today's society has been radically transformed, especially in developed economies. The stakeholders have deposited on companies different expectations compared to some years ago. Furthermore, this transformation has led to the establishment of new internal models of corporate governance depending on the intensity of the impact of demand for social action coming from the stakeholders interacting with firms. The aim of this work is to offer a decision model on Corporate Social Responsibility (CSR) and business strategies. This model constitutes a tool that can be adopted by firms, no matter their operational sector, to establish their particular coordinates with respe…
Atypical perceptual narrowing in prematurely born infants is associated with compromised language acquisition at 2 years of age
2010
Abstract Background Early auditory experiences are a prerequisite for speech and language acquisition. In healthy children, phoneme discrimination abilities improve for native and degrade for unfamiliar, socially irrelevant phoneme contrasts between 6 and 12 months of age as the brain tunes itself to, and specializes in the native spoken language. This process is known as perceptual narrowing, and has been found to predict normal native language acquisition. Prematurely born infants are known to be at an elevated risk for later language problems, but it remains unclear whether these problems relate to early perceptual narrowing. To address this question, we investigated early neurophysiolog…
The peach volatilome modularity is reflected at the genetic and environmental response levels in a QTL mapping population
2014
Background: The improvement of fruit aroma is currently one of the most sought-after objectives in peach breeding programs. To better characterize and assess the genetic potential for increasing aroma quality by breeding, a quantity trait locus (QTL) analysis approach was carried out in an F-1 population segregating largely for fruit traits. Results: Linkage maps were constructed using the IPSC peach 9 K Infinium (R) II array, rendering dense genetic maps, except in the case of certain chromosomes, probably due to identity-by-descent of those chromosomes in the parental genotypes. The variability in compounds associated with aroma was analyzed by a metabolomic approach based on GC-MS to pro…
Fixed point theorems for $\alpha$-$\psi$-contractive type mappings
2012
In this paper, we introduce a new concept of $\alpha$-$\psi$-contractive type mappings and establish fixed point theorems for such mappings in complete metric spaces. Starting from the Banach contraction principle, the presented theorems extend, generalize and improve many existing results in the literature. Moreover, some examples and applications to ordinary differential equations are given here to illustrate the usability of the obtained results.
Probabilistic floodplain hazard mapping: managing uncertainty by using a bivariate approach for flood frequency analysis
2014
Floods are a global problem and are considered the most frequent natural disaster world-wide. Many studies show that the severity and frequency of floods have increased in recent years and underline the difficulty to separate the effects of natural climatic changes and human influences as land management practices, urbanization etc. Flood risk analysis and assessment is required to provide information on current or future flood hazard and risks in order to accomplish flood risk mitigation, to propose, evaluate and select measures to reduce it. Both components of risk can be mapped individually and are affected by multiple uncertainties as well as the joint estimate of flood risk. Major sour…